KEGG   ORTHOLOGY: K12784
Entry
K12784                      KO                                     
Symbol
tir
Name
translocated intimin receptor
Pathway
map05130  Pathogenic Escherichia coli infection
Module
M00542  EHEC/EPEC pathogenicity signature, T3SS and effectors
Network
nt06180  Pathogenic Escherichia coli
nt06517  TLR signaling
  Element
N00926  Escherichia Tir to TLR2/4-MAPK signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01093  Escherichia EspJ/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K12784  tir; translocated intimin receptor
Genes
ECE: Z5112(tir)
ECS: ECs_4561(tir)
ECF: ECH74115_5056
ETW: ECSP_4676(tir)
ELX: CDCO157_4295
EOI: ECO111_3745(tir)
EOJ: ECO26_5278(tir)
EOH: ECO103_3611(tir)
ECOO: ECRM13514_4695(tir)
ECOH: ECRM13516_4478(tir)
ECG: E2348C_3941(tir)
EOK: G2583_4416(tir)
CRO: ROD_29851(tir)
 » show all
Reference
  Authors
Matsuzawa T, Kuwae A, Yoshida S, Sasakawa C, Abe A.
  Title
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1.
  Journal
EMBO J 23:3570-82 (2004)
DOI:10.1038/sj.emboj.7600359
Reference
  Authors
Brady MJ, Campellone KG, Ghildiyal M, Leong JM
  Title
Enterohaemorrhagic and enteropathogenic Escherichia coli Tir proteins trigger a common Nck-independent actin assembly pathway.
  Journal
Cell Microbiol 9:2242-53 (2007)
DOI:10.1111/j.1462-5822.2007.00954.x
  Sequence
[ecs:ECs_4561]
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