KEGG ORTHOLOGY: K16748

ORTHOLOGY: K16748

Entry

K16748                      KO

Symbol

BBS5

Name

Bardet-Biedl syndrome 5 protein

Disease

H00418

Bardet-Biedl syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K16748  BBS5; Bardet-Biedl syndrome 5 protein
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  BBSome
   K16748  BBS5; Bardet-Biedl syndrome 5 protein

Other DBs

GO:

0034464

Genes

HSA:	129880(BBS5)

PTR:	459714(BBS5)

PPS:	100981691(BBS5)

GGO:	101129617(BBS5)

PON:	100455960(BBS5)

PPYG:

129031105(BBS5)

NLE:	100580539(BBS5)

HMH:	116810696(BBS5)

SSYN:

129488014(BBS5)

MCC:	709701(BBS5)

MCF:	101865542(BBS5)

MTHB:

126932013

MNI:	105483279(BBS5)

CSAB:

103217267(BBS5)

CATY:

105579763(BBS5)

PANU:

101010893(BBS5)

TGE:	112635918(BBS5)

MLEU:

105545286(BBS5)

RRO:	104655038(BBS5)

RBB:	108516833(BBS5)

TFN:	117094894(BBS5)

PTEH:

111524513(BBS5)

CANG:

105525067(BBS5)

CJC:	100402122(BBS5)

CIMI:

108295252(BBS5)

ANAN:

105717544

CSYR:

103249885(BBS5)

MMUR:

105880690(BBS5)

LCAT:

123643279(BBS5)

PCOQ:

105815504(BBS5)

OGA:	100963365(BBS5)

MMU:	72569(Bbs5)

MCAL:

110289421(Bbs5)

MPAH:

110318808(Bbs5)

RNO:	362142(Bbs5)

ANU:	117703410(Bbs5)

ASYL:

127685428(Bbs5)

CGE:	100762765(Bbs5)

MAUA:

101844072(Bbs5)

PROB:

127222446(Bbs5)

PLEU:

114701806(Bbs5)

MORG:

121433295(Bbs5)

MFOT:

126489072

NGI:	103737986(Bbs5)

HGL:	101718158(Bbs5)

CPOC:

100713052(Bbs5)

CCAN:

109689228(Bbs5)

NCAR:

124979229

MMMA:

107136904(Bbs5)

ITI:	101969581(Bbs5)

OCU:

100342443

OPI:	101535809(BBS5)

TUP:	102480849(BBS5)

GVR:	103605879(BBS5)

CFA:	478783(BBS5)

CLUD:

112668057(BBS5)

VVP:	112916435(BBS5)

VLG:	121472271(BBS5)

NPO:	129498910(BBS5)

AML:	100472844(BBS5)

UMR:	103659537(BBS5)

UAH:	113250801(BBS5)

UAR:	123781004(BBS5)

ELK:

111142020

LLV:

125095684

MPUF:

101693157(BBS5)

MNP:	132012992(BBS5)

MLK:	131827124(BBS5)

NVS:	122902570(BBS5)

ORO:	101370000(BBS5)

EJU:	114225767(BBS5)

ZCA:	113919759(BBS5)

MLX:	118012353(BBS5)

NSU:	110591994(BBS5)

LWW:	102734869(BBS5)

FCA:	101087595(BBS5)

PYU:	121030667(BBS5)

PCOO:

112848482(BBS5)

PBG:	122481427(BBS5)

PVIV:

125173231(BBS5)

LRUF:

124516505

LGF:	123599042(BBS5)

AJU:

106987598

PTG:	102969798(BBS5)

PPAD:

109272577(BBS5)

HHV:	120242831(BBS5)

BTA:	528191(BBS5)

BOM:	102274128(BBS5)

BIU:	109566741(BBS5)

BBUB:

102416549(BBS5)

BBIS:

104995510(BBS5)

CHX:	102173694(BBS5)

OAS:	101120552(BBS5)

BTAX:

128071498(BBS5)

CSUM:

138076694(BBS5)

ODA:	120854895(BBS5)

CCAD:

122453594(BBS5)

MREE:

136163463(BBS5)

OVR:	110129435(BBS5)

MBEZ:

129538310(BBS5)

SSC:	100156983(BBS5)

CFR:	102506547(BBS5)

CBAI:

105081984(BBS5)

CDK:	105091067(BBS5)

VPC:	102537927(BBS5)

BACU:

103004520(BBS5)

BMUS:

118897794(BBS5)

LVE:	103078922(BBS5)

OOR:	101284568(BBS5)

LALB:

132522319(BBS5)

DLE:	111172838(BBS5)

PCAD:

102977411(BBS5)

PSIU:

116756415(BBS5)

NASI:

112410720(BBS5)

ECB:	100052477(BBS5)

EPZ:	103554222(BBS5)

EAI:	106843556(BBS5)

MYB:	102249863(BBS5)

MYD:	102775545(BBS5)

MMYO:

118661926(BBS5)

MLF:	102424752(BBS5)

MDT:	132238561(BBS5)

PKL:	118709686(BBS5)

EFUS:

103283342(BBS5)

MNA:	107527792(BBS5)

DRO:	112322242(BBS5)

SHON:

118985735(BBS5)

AJM:	119045842(BBS5)

PDIC:

114494351(BBS5)

PHAS:

123806519(BBS5)

MMF:	118625267(BBS5)

PPAM:

129061876(BBS5)

RFQ:	117025604(BBS5)

PALE:

102897961(BBS5)

PGIG:

120596925(BBS5)

PVP:	105290720(BBS5)

RAY:	107521041(BBS5)

MJV:	108397184(BBS5)

SARA:

101552857(BBS5)

SFUM:

130019698(BBS5)

SETR:

126009111(BBS5)

LAV:	100669256(BBS5)

TMU:

101350885

ETF:	101642351(BBS5)

DNM:	101427732(BBS5)

MDO:	100017368(BBS5)

GAS:	123239266(BBS5)

AFZ:

127554573

PCW:	110211632(BBS5)

TVP:	118838875(BBS5)

OAA:	100077415(BBS5)

TACU:

119931999(BBS5)

GGA:	424165(BBS5)

PCOC:

116232876(BBS5)

MGP:	100543160(BBS5)

CJO:	107316733(BBS5)

TPAI:

128076802(BBS5)

LMUT:

125696859(BBS5)

NMEL:

110400141(BBS5)

APLA:

106016917(BBS5)

ACYG:

106029970(BBS5)

CATA:

118243068(BBS5)

AFUL:

116490862(BBS5)

TGU:	100222660(BBS5)

LSR:	110472770(BBS5)

SCAN:

103814415(BBS5)

PMOA:

120496782(BBS5)

OTC:	121335514(BBS5)

PRUF:

121356643(BBS5)

ATRC:

139593708(BBS5)

GFR:	102041544(BBS5)

FAB:	101817997(BBS5)

OMA:	130266840(BBS5)

PHI:	102113051(BBS5)

PMAJ:

107207543(BBS5)

CCAE:

111932113(BBS5)

CCW:	104693897(BBS5)

CBRC:

103616646(BBS5)

ACOE:

138112996(BBS5)

ETL:	114073758(BBS5)

ZAB:	102064513(BBS5)

ZLE:	135450135(BBS5)

ACHL:

103806286(BBS5)

SVG:	106862109(BBS5)

MMEA:

130576798(BBS5)

HRT:	120754906(BBS5)

SATI:

136363522(BBS5)

CCIC:

134047298(BBS5)

FPG:	101921165(BBS5)

FCH:	102052958(BBS5)

CCRI:

104165728(BBS5)

NNT:	104400203(BBS5)

SHAB:

115608009(BBS5)

ACUN:

113482117(BBS5)

TALA:

122152439(BBS5)

ACHC:

115343245(BBS5)

HALD:

104310824(BBS5)

HLE:	104831542(BBS5)

AGEN:

126043446

HHAR:

128144303(BBS5)

GCL:

127018344

CSTI:

104550350(BBS5)

LDI:	104340515(BBS5)

MNB:	103771781(BBS5)

DPUB:

104304713(BBS5)

PPUS:

135186081(BBS5)

AVIT:

104278068(BBS5)

BRHI:

104499237(BBS5)

EGZ:	104128002(BBS5)

NNI:	104009983(BBS5)

PCRI:

104039035(BBS5)

PCAO:

104047999(BBS5)

PADL:

103918191(BBS5)

AFOR:

103898313(BBS5)

FGA:	104081521(BBS5)

GSTE:

104254414(BBS5)

CBOY:

140657563(BBS5)

CLV:	102094283(BBS5)

MUI:	104542677(BBS5)

PGUU:

104462063(BBS5)

PLET:

104626126(BBS5)

EHS:	104508271(BBS5)

CMAC:

104473842(BBS5)

CUCA:

104054546(BBS5)

TEO:	104370281(BBS5)

BREG:

104643447(BBS5)

OHA:	104329044(BBS5)

ACAR:

104522363(BBS5)

CPEA:

104387529(BBS5)

CVF:	104294900(BBS5)

RTD:	128912647(BBS5)

CRID:

134518885(BBS5)

AAM:	106499191(BBS5)

AROW:

112974986(BBS5)

NPD:	112943582(BBS5)

TGT:	104570464(BBS5)

DNE:	112979486(BBS5)

SCAM:

104138357(BBS5)

ASN:	102381397(BBS5)

AMJ:	102572563(BBS5)

CPOO:

109323127(BBS5)

GGN:	109301540(BBS5)

PSS:	102448167(BBS5)

CMY:	102934097(BBS5)

CCAY:

125644987(BBS5)

DCC:	119863401(BBS5)

CPIC:

101949204(BBS5)

TST:	117884696(BBS5)

CABI:

116819372(BBS5)

MRV:	120375178(BBS5)

ACS:	100559089(bbs5)

ASAO:

132776727(BBS5)

PVT:	110076915(BBS5)

SUND:

121925851(BBS5)

PBI:	103061246(BBS5)

PMUR:

107297958(BBS5)

CTIG:

120318126(BBS5)

PGUT:

117671181(BBS5)

APRI:

131202269(BBS5)

PTEX:

113434096(BBS5)

NSS:	113423590(BBS5)

VKO:	123017069(BBS5)

PMUA:

114606091(BBS5)

PRAF:

128423737(BBS5)

ZVI:	118093734(BBS5)

HCG:	128331530(BBS5)

GJA:	107119691(BBS5)

STOW:

125426078(BBS5)

EMC:	129323940(BBS5)

XLA:	447606(bbs5.L)

XTR:	548992(bbs5)

NPR:	108785498(BBS5)

RTEM:

120944041(BBS5)

BBUF:

121007807(BBS5)

BGAR:

122944363(BBS5)

PWL:	138285404(BBS5)

MUO:	115474820(BBS5)

GSH:	117361077(BBS5)

DRE:	393269(bbs5)

SRX:	107744839(bbs5) 107749971

SANH:

107656522(bbs5)

SGH:

107566768

CCAR:

109069678 109082257(bbs5)

CAUA:

113052954(bbs5) 113109300

CGIB:

127965392 128020081

PTET:

122351290(bbs5)

LROH:

127170914(bbs5)

OMC:	131546887(bbs5)

PPRM:

120486998(bbs5) 120487372

RKG:	130105458(bbs5)

MAMB:

125270728(bbs5)

CIDE:

127518977

CERY:

137036450(bbs5)

MASI:

127447630 127448419

TROS:

130555362(bbs5)

TDW:	130427631(bbs5)

MANU:

129451787(bbs5)

PDAB:

135733096(bbs5)

IPU:	100528105(bbs5)

IFU:	128609002(bbs5)

PHYP:

113526129(bbs5)

SMEO:

124383046(bbs5)

TFD:	113654170(bbs5)

TVC:	132850321(bbs5)

CGAR:

128524423(bbs5)

NGRA:

132891991(bbs5)

TRN:	134324403(bbs5)

AMEX:

103043779(bbs5)

CMAO:

118810343(bbs5)

EEE:	113584298(bbs5)

CHAR:

105912659(bbs5)

SPIL:

134078764(bbs5)

TRU:	101069724(bbs5)

TFS:	130527164(bbs5)

TNG:	GSTEN00031402G001

LCO:	104931037(bbs5)

NCC:	104948285(bbs5)

TBEN:

117481194(bbs5)

CGOB:

115026450(bbs5)

PGEO:

117466698(bbs5)

GACU:

117544448(bbs5)

EMAC:

134867216(bbs5)

ELY:	117251121(bbs5)

EFO:	125899701(bbs5)

PLEP:

121949534(bbs5)

SLUC:

116048804(bbs5)

ECRA:

117952637(bbs5)

ESP:	116697642(bbs5)

PFLV:

114564314(bbs5)

GAT:	120833836(bbs5)

PPUG:

119229369(bbs5)

AFB:	129104791(bbs5)

CLUM:

117750550(bbs5)

PSWI:

130208608(bbs5)

CANA:

137782496(bbs5)

CVE:	137890809(bbs5)

MSAM:

119904083(bbs5)

SCHU:

122885219(bbs5)

CUD:	121522763(bbs5)

SPUL:

138592527(bbs5)

LMIX:

132987384(bbs5)

ALAT:

119025798(bbs5)

ASTR:

137605115(bbs5)

MZE:	101471885(bbs5)

ONL:	100704965(bbs5)

OAU:	116322981(bbs5)

OLA:	101157654(bbs5)

OML:	112154723(bbs5)

CSAI:

133446451(bbs5)

XMA:	102229200(bbs5)

XCO:	114147781(bbs5)

XHE:	116722677(bbs5)

PRET:

103458777(bbs5)

PFOR:

103134268(bbs5)

PLAI:

106955135(bbs5)

PMEI:

106923125(bbs5)

GAF:	122839659(bbs5)

PPRL:

129361029(bbs5)

CVG:	107093549(bbs5)

CTUL:

119793917(bbs5)

GMU:	124871188(bbs5)

NFU:	107390044(bbs5)

KMR:	108240737(bbs5)

ALIM:

106512918(bbs5)

NWH:	119419133(bbs5)

AOCE:

111579205(bbs5)

EJA:	138200842(bbs5)

BFRE:

138623178(bbs5)

MCEP:

125017847(bbs5)

CSEM:

103392220(bbs5)

POV:	109631221(bbs5)

SSEN:

122765531(bbs5)

SSOE:

131444791(bbs5)

HHIP:

117754728(bbs5)

HSP:	118120055(bbs5)

PPLT:

128456439(bbs5)

SMAU:

118283146(bbs5)

LCF:

108888652

SDU:	111218298(bbs5)

SLAL:

111653062(bbs5)

XGL:	120801287(bbs5)

HCQ:	109520190(bbs5)

SSCV:

125973301(bbs5)

SBIA:

133512157(bbs5)

PEE:	133410928(bbs5)

PTAO:

133487282(bbs5)

BPEC:

110166650(bbs5)

ENY:	140359159(bbs5)

MALB:

109958033(bbs5)

BSPL:

114847148(bbs5)

SJO:	128367736(bbs5)

SSCO:

133992525(bbs5)

GMH:	115532986(bbs5)

SASA:

100195588(bbs5)

STRU:

115156040(bbs5)

OTW:

112225217

OMY:	110501475(bbs5)

OGO:

124042912

ONE:	115146415(bbs5)

OKI:	109871386(bbs5)

OKE:

118386022

OMM:

135547203

OCLA:

139380067

SALP:

111959942(bbs5)

SNH:

120063834

CCLU:

121536118 121552311

ELS:	105022469(bbs5)

OEP:	134017841(bbs5)

SFM:	108920228 108927893

PKI:	111833188 111852295

AANG:

118223084(bbs5)

AROT:

135251989(bbs5)

LOC:	102693311(bbs5)

PSPA:

121322702

ARUT:

117405508(bbs5) 117426768

PSEX:

120531815(bbs5)

LCM:	102349996(BBS5)

CMK:	103176443(bbs5) 121849377

RTP:	109936590(bbs5)

CPLA:

122551570(bbs5)

HOC:	132817469(bbs5)

LERI:

129698754(bbs5)

PMRN:

116938568(BBS5) 116951410

LRJ:	133340620 133346068

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG1126(BBS5)

DER:

6552096

DSE:

6613872

DSI:	Dsimw501_GD19751(Dsim_GD19751)

DYA:	Dyak_GE25437

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10244

DAZ:

108621010

DNV:

108659204

DHE:

111595738

DVI:	6632635(BBS5)

CCAT:

101458838

BOD:

106617065

BDR:

105226529

RZE:	108375085 108382286

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135948934(BBS5)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ015694

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139108247(Bbs5)

TLN:	139822523(Bbs5)

HST:

DQU:

CFO:

FEX:

PMEC:

138939293(Bbs5)

LHU:	105673211(BBS5)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

TCA:

TMOL:

138140483(BBS5)

ESIM:

136408875(BBS5)

EFOR:

136345378(BBS5)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:	111514298 111514299

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

MSEX:

DPL:	KGM_215205

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137920400(BBS5)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFEL:

113366014 113366023 113367129 113367150 113367155 113380613

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106684078(BBS5)

NLU:

111062022

HVI:

124360362

MQU:	128991683 128992581

PHU:	Phum_PHUM599810

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138709239(BBS5)

SGRE:

126299350

BROR:

134537396

IEL:

124165802

HAMR:

139694709(BBS5)

FCD:	110855842 110862190

DPX:	DAPPUDRAFT_327755

DMK:

116922956

DPZ:

124320942

AFRA:

136031462 136031589

PVM:	113804961(BBS5)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123755473(BBS5)

CQD:	128696381(BBS5)

PTRU:

123504862

ESN:

126996479

MNZ:

135221966

MRJ:	136843838(BBS5)

PORN:

139761716(BBS5)

HAZT:

108667691

EAF:

111716848

LSM:	121125388(BBS5)

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136973178(BBS5)

PTEP:

ABRU:

SDM:

LPOL:

PMEO:

CEL:	CELE_R01H10.6(bbs-5)

CBR:	CBG_23799(Cbr-bbs-5)

CRQ:	GCK72_010510

NAI:	NECAME_02517

BMY:	BM_BM5173(Bma-bbs-5)

LOA:	LOAG_10131

HRO:	HELRODRAFT_108097

LGI:	LOTGIDRAFT_207456

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:	106869652 106871256

OSN:	115216207 115216623

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:	114516075 114531309

XEN:	124440722 124456389

HMG:

100212616

HSY:

130622465

RES:

135682698

TAD:	TRIADDRAFT_50116

AQU:	100635647 100641068

CRE:	CHLRE_06g267550v5

VCN:	VOLCADRAFT_78967(bbs5)

MIS:	MICPUN_87458

MPP:	MICPUCDRAFT_34174

MBR:	MONBRDRAFT_32801

SRE:	PTSG_01591

TGO:	TGME49_259965

TET:	TTHERM_00782070

PTM:	GSPATT00034169001 GSPATT00036912001

AAF:	AURANDRAFT_72072

PIF:	PITG_05883

PSOJ:

PHYSODRAFT_515023

SPAR:

SPRG_04058

TBR:	TB927.1.4140

TBG:	TbgDal_I2680

TCR:

510889.20

LMA:	LMJF_12_0680

LIF:	LINJ.12.0630

LDO:	LDBPK_120630

LMI:	LMXM_12_0680

LMAT:

92517743(LSCM1_07879)

LBZ:	LBRM_12_0680

LPAN:

LPMP_120680

LOI:	92363478(LSCM4_07665)

LEIS:

94183562(GH5_08358)

LENR:

94175444(CUR178_08305)

LEIN:

94191929(JIQ42_08374)

PHET:

94293529(JKF63_07515)

NGR:	NAEGRDRAFT_34252

TVA:	4751906(TVAGG3_0040600)

GLA:	GL50803_008146

SSAO:

94302115(SS50377_28092)

EHX:	EMIHUDRAFT_63258

GTT:	GUITHDRAFT_135519

» show all

Reference

PMID:17574030

Authors

Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peranen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK

Title

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Journal

Cell 129:1201-13 (2007)
DOI:10.1016/j.cell.2007.03.053

Sequence

[hsa:129880]

LinkDB

DBGET integrated database retrieval system