KEGG   ORTHOLOGY: K21283
Entry
K21283                      KO                                     
Symbol
BMP2
Name
bone morphogenetic protein 2
Pathway
map04060  Cytokine-cytokine receptor interaction
map04350  TGF-beta signaling pathway
map04390  Hippo signaling pathway
map05200  Pathways in cancer
map05217  Basal cell carcinoma
Disease
H00482  Brachydactyly
H02481  Syndromic disorder with short stature
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K21283  BMP2; bone morphogenetic protein 2
   04390 Hippo signaling pathway
    K21283  BMP2; bone morphogenetic protein 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K21283  BMP2; bone morphogenetic protein 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K21283  BMP2; bone morphogenetic protein 2
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    K21283  BMP2; bone morphogenetic protein 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K21283  BMP2; bone morphogenetic protein 2
   00536 Glycosaminoglycan binding proteins
    K21283  BMP2; bone morphogenetic protein 2
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K21283  BMP2; bone morphogenetic protein 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K21283  BMP2; bone morphogenetic protein 2
Other DBs
GO: 0070700
Genes
HSA: 650(BMP2)
PTR: 458090(BMP2)
PPS: 100967346(BMP2)
GGO: 101149410(BMP2)
PON: 100460853(BMP2)
NLE: 100586297(BMP2)
MCC: 718330(BMP2)
MCF: 102145501(BMP2)
MTHB: 126964143
CSAB: 103246725(BMP2)
CATY: 105582098(BMP2)
PANU: 101025190(BMP2)
TGE: 112633180(BMP2)
RRO: 104681477(BMP2)
RBB: 108525104 108533001(BMP2)
TFN: 117068478(BMP2)
PTEH: 111546455(BMP2)
CANG: 105511004(BMP2)
CJC: 100408260(BMP2)
SBQ: 101050026(BMP2)
CSYR: 103269536(BMP2)
MMUR: 105866089(BMP2)
LCAT: 123622305(BMP2)
PCOQ: 105806184(BMP2)
OGA: 100952817(BMP2)
MMU: 12156(Bmp2)
MCAL: 110289488(Bmp2)
MPAH: 110318284(Bmp2)
RNO: 29373(Bmp2)
MCOC: 116090993(Bmp2)
MUN: 110557991(Bmp2)
CGE: 100752564(Bmp2)
MAUA: 101833665(Bmp2)
PLEU: 114699539(Bmp2)
MORG: 121460473(Bmp2)
MFOT: 126496732
AAMP: 119814518(Bmp2)
NGI: 103725543(Bmp2)
HGL: 101723419(Bmp2)
CPOC: 100732974(Bmp2)
CCAN: 109677386(Bmp2)
DORD: 105981433(Bmp2)
DSP: 122120543(Bmp2)
NCAR: 124978309
OCU: 100009349(BMP2)
OPI: 101523631(BMP2)
TUP: 102469552(BMP2)
GVR: 103609832(BMP2)
CFA: 477162(BMP2)
CLUD: 112673617(BMP2)
VVP: 112930056(BMP2)
VLG: 121478407(BMP2)
AML: 100465860(BMP2)
UMR: 103674423(BMP2)
UAH: 113258350(BMP2)
UAR: 123799694(BMP2)
ELK: 111141639
LLV: 125109434
MPUF: 101677371(BMP2)
ORO: 101367237(BMP2)
EJU: 114216361(BMP2)
ZCA: 113938590(BMP2)
MLX: 118011254(BMP2)
NSU: 110579363(BMP2)
LWW: 102731853(BMP2)
FCA: 100301987(BMP2)
PYU: 121012472(BMP2)
PBG: 122496555(BMP2)
LRUF: 124504345
PTG: 102961685(BMP2)
PPAD: 109274726(BMP2)
AJU: 106976426(BMP2)
HHV: 120226397(BMP2)
BTA: 615037(BMP2)
BOM: 102268860(BMP2)
BIU: 109567176(BMP2)
BBUB: 102408388(BMP2)
BBIS: 104986042(BMP2)
CHX: 100860831(BMP2)
OAS: 101117688(BMP2)
ODA: 120868917(BMP2)
CCAD: 122448237(BMP2)
SSC: 100157103(BMP2)
CFR: 102514653(BMP2)
CBAI: 105083060(BMP2)
CDK: 105101322(BMP2)
VPC: 102528775(BMP2)
BACU: 103004284(BMP2)
LVE: 103070700(BMP2)
OOR: 101269813(BMP2)
DLE: 111165639(BMP2)
PCAD: 102978631(BMP2)
PSIU: 116740858(BMP2)
ECB: 100051701(BMP2)
EPZ: 103563779(BMP2)
EAI: 106823202(BMP2)
MYB: 102241256(BMP2)
MYD: 102768711(BMP2)
MMYO: 118662859(BMP2)
MLF: 102427988(BMP2)
MNA: 107536373(BMP2)
PKL: 118707552(BMP2)
HAI: 109383815(BMP2)
DRO: 112304048(BMP2)
SHON: 118990873(BMP2)
AJM: 119051190(BMP2)
PDIC: 114506674(BMP2)
PHAS: 123815283(BMP2)
MMF: 118618684(BMP2)
RFQ: 117016157(BMP2)
PALE: 102886941(BMP2)
PGIG: 120603409(BMP2)
PVP: 105298720(BMP2)
RAY: 107511521(BMP2)
MJV: 108403876(BMP2)
TOD: 119232694(BMP2)
SARA: 101548404(BMP2)
LAV: 100654878(BMP2)
ETF: 101648616(BMP2)
DNM: 101423691(BMP2)
MDO: 100031674(BMP2)
GAS: 123234308 123234746(BMP2)
SHR: 100935094(BMP2)
PCW: 110207865(BMP2) 110215386
OAA: 100084030(BMP2) 114810112
GGA: 112532694 378779(BMP2)
PCOC: 116231818(BMP2) 116238163
MGP: 100549917(BMP2) 104911967
CJO: 107310979(BMP2) 107315785
NMEL: 110396085(BMP2) 110400626
APLA: 106016176(BMP2) 106017909
ACYG: 106036603(BMP2)
AFUL: 116487650(BMP2) 116491316
OTC: 121341712 121342635(BMP2)
PRUF: 121350125 121357049(BMP2)
CBRC: 103623019(BMP2) 108444666
ZAB: 102062522(BMP2) 106630734
ACHL: 103807234(BMP2) 103810317
FPG: 101922026(BMP2) 106112594
FCH: 102048793(BMP2) 106631726
EGZ: 104128703(BMP2) 104129039
NNI: 104022480(BMP2)
PCRI: 104027180(BMP2)
PCAO: 104046116 104047620(BMP2)
ACUN: 113477994(BMP2) 113481610
TALA: 104360661 104366608(BMP2)
PADL: 103913163(BMP2) 103913979
AFOR: 103897828 103901640(BMP2)
ACHC: 115344649(BMP2) 115348327
HALD: 104320973 104322454(BMP2)
HLE: 104829341 104836449(BMP2)
CSTI: 104551024 104552255(BMP2)
CMAC: 104473434 104475783(BMP2)
MUI: 104545809(BMP2)
FGA: 104070873 104080408(BMP2)
LDI: 104347181(BMP2) 104354202
MNB: 103768326(BMP2) 103782019
OHA: 104330458 104330727(BMP2)
NNT: 104403325 104405183(BMP2)
DPUB: 104297779 104305986(BMP2)
PGUU: 104460633(BMP2)
ACAR: 104527934 104530595(BMP2)
CPEA: 104391131 104397208(BMP2)
AVIT: 104268673 104277986(BMP2)
CVF: 104287383(BMP2) 104289801
CUCA: 104055437(BMP2) 104067961
TEO: 104374331 104377831(BMP2)
BRHI: 104495773(BMP2) 104500291
AAM: 106490352(BMP2) 106497809
AROW: 112965313(BMP2) 112971439
NPD: 112958058 112958934(BMP2)
DNE: 112980106(BMP2) 112989065
SCAM: 104143486(BMP2)
AMJ: 102564323(BMP2) 102574161(ADMP) 102575698
CPOO: 109319038(BMP2) 109323853
GGN: 109287147 109296705(BMP2)
CABI: 116816947 116824056(BMP2)
MRV: 120400009(BMP2) 120409511
ACS: 100560955(bmp2) 103279318
PBI: 103059412(BMP2) 103064164
PMUR: 107285368(BMP2) 107299617
CTIG: 120312041 120315300(BMP2)
TSR: 106540084 106550496(BMP2)
PGUT: 117674357(BMP2) 117677687
VKO: 123030433(BMP2)
STOW: 125434709(BMP2)
XLA: 100036830(admp2.L) 378780(bmp2.S) 397873(bmp2.L)
XTR: 100494614(admp2) 548717(bmp2)
RTEM: 120909121 120938036(BMP2)
BBUF: 120998902(BMP2)
BGAR: 122934895(BMP2)
DRE: 100329171(bmp16) 140619(admp) 30631(bmp2a) 30632(bmp2b)
PPRM: 120460008(bmp16) 120460158(bmp2b) 120460862 120464126(bmp2a) 120466737
MAMB: 125251577 125254347(bmp16) 125255729 125269304(bmp2a) 125278460(bmp2b)
IPU: 108258023(bmp2b) 108264167(bmp16) 108270435(bmp2a) 108280256(admp)
SMEO: 124376521(bmp2b) 124388798 124390595(bmp2a) 124395979(bmp16) 124402754
TFD: 113644575(bmp2b) 113645282 113649645(bmp16) 113650676 113659797(bmp2a)
ELY: 117247730 117260320(bmp16) 117270466(bmp2b) 117271446(admp)
PLEP: 121943754(bmp16) 121950954 121955429(bmp2b) 121958473
SLUC: 116041940(bmp2b) 116045259 116046871 116047725(bmp16)
ECRA: 117936760 117942173(bmp16) 117954482(admp) 117961092(bmp2b)
PPUG: 119194536(bmp2b) 119209707 119213302 119217593(bmp16)
MSAM: 119883176(bmp16) 119903030 119908523(bmp2b) 119916133
ALAT: 119009700 119011305 119012936(bmp16) 119013049(bmp2b)
OML: 112141371 112147395(admp) 112149994(bmp16) 112157608(bmp2b)
GAF: 122825009(bmp2b) 122833260(bmp16) 122841088
CTUL: 119784161(bmp2b) 119785221 119797332(bmp16)
NWH: 119411253(bmp16) 119418474(bmp2b) 119429488
MCEP: 124999546(bmp2b) 125010208 125013998(bmp16) 125022791
HHIP: 117752834 117758548(bmp2b) 117772981(bmp16) 117778230(admp)
HSP: 118099031(bmp2b) 118106647(bmp16) 118118153
BSPL: 114845015 114846039 114849955(bmp2b) 114867783(bmp16)
AANG: 118208857(bmp16) 118212320(bmp2a) 118221525 118225371(admp) 118229327(bmp2b)
PSEX: 120516503(bmp2a) 120519125 120538679(bmp16)
CMK: 103186457(bmp2a)
RTP: 109915138(bmp2) 109930532
BFO: 118411660
AJC: 117111673
SKO: 100303514(bmp2/4) 100303522(admp) 100313546(Admp2) 100313762 102800705
ACER: 108001792
CFO: 105258916
TPRE: 106655281
LHT: 122511199
SOY: 115890345
OTU: 111423741
PNAP: 125055028
CFEL: 113366714
DNX: 107167002
TPAL: 117644110
DMK: 116931925
DPZ: 124350950
HAZT: 108664624
PPOI: 119111802
TUT: 107365276
DPTE: 113793239
CSCU: 111621682
BMY: BM_BM2914(Bma-dbl-1)
PCAN: 112569894
BGT: 106066197
GAE: 121370342
EPA: 110243875
ATEN: 116302105
ADF: 107334071(AdiBmp2/4) 107337024
DGT: 114532337
XEN: 124437008
 » show all
Reference
PMID:3201241
  Authors
Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA
  Title
Novel regulators of bone formation: molecular clones and activities.
  Journal
Science 242:1528-34 (1988)
DOI:10.1126/science.3201241
  Sequence
[hsa:650]
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