KEGG   MODULE: M00569
Entry
M00569            Pathway   Module                                 
Name
Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Definition
(K00446,K07104) ((K10217 K01821 K01617),K10216) (K18364,K02554) (K18365,K01666) (K18366,K04073)
Diagram
M00569

Orthology
K00446,K07104  
catechol 2,3-dioxygenase [EC:1.13.11.2] [RN:R00816 R05295]
K10217  
2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.85] [RN:R02762 R05353]
K01821  
4-oxalocrotonate tautomerase [EC:5.3.2.6] [RN:R03966 R05389]
K01617  
4-oxalocrotonate decarboxylase [EC:4.1.1.77] [RN:R02602 R05374]
K10216  
2-hydroxymuconate-semialdehyde hydrolase [EC:3.7.1.9] [RN:R02604 R05865]
K18364  
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132] [RN:R02601 R05864]
K02554  
2-keto-4-pentenoate hydratase [EC:4.2.1.80] [RN:R02601]
K18365  
4-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase [EC:4.1.3.39 4.1.3.43] [RN:R00750 R05298]
K01666  
4-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39] [RN:R00750]
K18366  
acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87] [RN:R00228 R09097]
K04073  
acetaldehyde dehydrogenase [EC:1.2.1.10] [RN:R00228]
Class
Pathway modules; Xenobiotics biodegradation; Aromatics degradation
Pathway
map00362  Benzoate degradation
map00622  Xylene degradation
map01220  Degradation of aromatic compounds
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R00816  
R02762  
R03966  
R02602  
R02604  
R02601  
R00750  
R00228  
R05295  
R05353  
R05389  
R05374  
R05865  
R05864  
R05298  
R09097  
Compound
C00090  Catechol
C00682  2-Hydroxymuconate semialdehyde
C02501  2-Hydroxymuconate
C03453  gamma-Oxalocrotonate
C00596  2-Hydroxy-2,4-pentadienoate
C03589  4-Hydroxy-2-oxopentanoate
C00022  Pyruvate
C00084  Acetaldehyde
C00024  Acetyl-CoA
C06730  4-Methylcatechol
C06760  2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
C07478  2-Hydroxy-5-methyl-cis,cis-muconate
C07479  2-Oxo-5-methyl-cis-muconate
C11354  2-Hydroxy-cis-hex-2,4-dienoate
C06762  4-Hydroxy-2-oxohexanoic acid
C00479  Propanal
C00100  Propanoyl-CoA
RModule
RM009  Meta-cleavage of dihydroxylated aromatic ring
LinkDB

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