Entry Name Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Definition K12250 K15907 -- K18056 K17747 K18091 K18057 K17476
Diagram M00819 Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Class Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other antibioticsBRITE hierarchy
Pathway map00998 Biosynthesis of various antibiotics
map01110 Biosynthesis of secondary metabolites
Orthology Ortholog table Taxonomy Complete sbh Streptomyces bingchenggensis
scw Streptomyces cyaneogriseus
sle Streptomyces leeuwenhoekii
ssia Streptomyces alfalfae
sgj Streptomyces genisteinicus
shk Streptomyces huasconensis
Reaction Compound C00448 trans,trans-Farnesyl diphosphate
C20403 1-Deoxy-11beta-hydroxypentalenate
C20400 1-Deoxy-11-oxopentalenate
Reference Authors Quaderer R, Omura S, Ikeda H, Cane DE
Title Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlI, a cytochrome P450 of Streptomyces avermitilis.
Journal Reference Authors Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE
Title Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
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