 | | MODULE: M00835 | |
| Entry |
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| Name |
Pyocyanine biosynthesis, chorismate => pyocyanine
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| Definition |
K13063 K20261 K06998 K20260 K20262 K21103 K20940
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| Diagram |
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| Orthology |
phzD; trans-2,3-dihydro-3-hydroxyanthranilic acid synthase [EC: 3.3.2.15][RN: R11463] phzF; trans-2,3-dihydro-3-hydroxyanthranilate isomerase [EC: 5.3.3.17] [RN: R09707] phzM; phenazine-1-carboxylate N-methyltransferase [EC: 2.1.1.327][RN: R11533] |
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| Class |
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other bacterial compounds
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| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
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| Reaction |
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| Compound |
| C18054 | 2-Amino-2-deoxyisochorismate |
| C19830 | (5S,6S)-6-Amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate |
| C19831 | (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate |
| C21473 | (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate |
| C21408 | (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate |
| C21411 | (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate |
| C21412 | (10aS)-10,10a-Dihydrophenazine-1-carboxylate |
| C20981 | 5,10-Dihydrophenazine-1-carboxylate |
| C21442 | Phenazine-1-carboxylate |
| C21295 | 5-Methylphenazine-1-carboxylate |
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| Reference |
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| Authors |
Xu N, Ahuja EG, Janning P, Mavrodi DV, Thomashow LS, Blankenfeldt W |
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| Title |
Trapped intermediates in crystals of the FMN-dependent oxidase PhzG provide insight into the final steps of phenazine biosynthesis. |
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| Journal |
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| Reference |
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| Authors |
Parsons JF, Greenhagen BT, Shi K, Calabrese K, Robinson H, Ladner JE |
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| Title |
Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. |
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| Journal |
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| LinkDB |
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