| Entry |
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| Name |
Shigella IpaC to Actin signaling pathway
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| Definition |
IpaC -> SRC -> CTTN -> ARP2/3 -> (ACTB,ACTG1) |
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| Expanded |
K13286 -> 6714 -> 2017 -> (10097+10096+10552+10095+10109+10094+10093+10092+81873) -> (60,71) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 6714 | SRC; SRC proto-oncogene, non-receptor tyrosine kinase |
| 10097 | ACTR2; actin related protein 2 |
| 10096 | ACTR3; actin related protein 3 |
| 10552 | ARPC1A; actin related protein 2/3 complex subunit 1A |
| 10095 | ARPC1B; actin related protein 2/3 complex subunit 1B |
| 10109 | ARPC2; actin related protein 2/3 complex subunit 2 |
| 10094 | ARPC3; actin related protein 2/3 complex subunit 3 |
| 10093 | ARPC4; actin related protein 2/3 complex subunit 4 |
| 10092 | ARPC5; actin related protein 2/3 complex subunit 5 |
| 81873 | ARPC5L; actin related protein 2/3 complex subunit 5 like |
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| Perturbant |
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| Reference |
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| Authors |
Mounier J, Popoff MR, Enninga J, Frame MC, Sansonetti PJ, Van Nhieu GT |
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| Title |
The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cells. |
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| Journal |
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| Reference |
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| Authors |
Bougneres L, Girardin SE, Weed SA, Karginov AV, Olivo-Marin JC, Parsons JT, Sansonetti PJ, Van Nhieu GT |
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| Title |
Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells. |
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| Journal |
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| Reference |
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| Authors |
Selbach M, Backert S |
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| Title |
Cortactin: an Achilles' heel of the actin cytoskeleton targeted by pathogens. |
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| Journal |
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| LinkDB |
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