KEGG   Homo sapiens (human): 10092
Entry
10092             CDS       T01001                                 
Symbol
ARPC5, ARC16, IMD113, dJ127C7.3, p16-Arc
Name
(RefSeq) actin-related protein 2/3 complex subunit 5 isoform 1
  KO
K05754  actin related protein 2/3 complex, subunit 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04517  IgSF CAM signaling
hsa04519  Cadherin signaling
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagosome formation
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
nt06549  Cadherin signaling
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
N02004  clustered PCDH signaling
Disease
H01725  Primary immunodeficiency disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    10092 (ARPC5)
   04519 Cadherin signaling
    10092 (ARPC5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10092 (ARPC5)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10092 (ARPC5)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10092 (ARPC5)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagosome formation
    10092 (ARPC5)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10092 (ARPC5)
   05132 Salmonella infection
    10092 (ARPC5)
   05131 Shigellosis
    10092 (ARPC5)
   05135 Yersinia infection
    10092 (ARPC5)
   05100 Bacterial invasion of epithelial cells
    10092 (ARPC5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10092 (ARPC5)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10092 (ARPC5)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10092 (ARPC5)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10092 (ARPC5)
SSDB
Motif
Pfam: P16-Arc Utp12 UTP15_C Glyoxalase_4
Other DBs
NCBI-GeneID: 10092
NCBI-ProteinID: NP_005708
OMIM: 604227
HGNC: 708
Ensembl: ENSP00000352918.6
UniProt: O15511
Structure
LinkDB
Position
1:complement(183620846..183635783)
AA seq 151 aa
MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALK
NPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDN
SSAMLLQWHEKALAAGGVGSIVRVLTARKTV
NT seq 456 nt   +upstreamnt  +downstreamnt
atgtcgaagaacacagtgtcgtcggcccgcttccggaaggtggacgtggatgaatatgac
gagaacaagttcgtggacgaagaagatgggggcgacggccaggccgggcccgacgagggc
gaggtggactcctgcctgcggcaaggaaacatgacagctgccctacaggcagctctgaag
aacccccctatcaacaccaagagtcaggcagtgaaggaccgggcaggcagcattgtcttg
aaggtgctcatctcttttaaagctaatgatatagaaaaggcagttcaatctctggacaag
aatggtgtggatctcctaatgaagtatatttataaaggatttgagagcccgtctgacaat
agcagtgctatgttactgcaatggcatgaaaaggcacttgctgctggaggagtagggtcc
attgttcgtgtcttgactgcaagaaaaactgtgtag

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