| Entry |
|
|---|
| Name |
Escherichia EspT to RAC signaling pathway
|
|---|
| Definition |
EspT -> RAC1 -> (WASF2+ABI1) -> ARP2/3 -> (ACTB,ACTG1) |
|---|
| Expanded |
K23651 -> 5879 -> (10163+10006) -> (10097+10096+10552+10095+10109+10094+10093+10092+81873) -> (60,71) |
|---|
| Class |
nt06180 Pathogenic Escherichia coli
|
|---|
| Type |
Pathogen
|
|---|
| Pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
|
|---|
| Disease |
| H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
| H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
|
|---|
| Gene |
| 5879 | RAC1; Rac family small GTPase 1 |
| 10163 | WASF2; WASP family member 2 |
| 10006 | ABI1; abl interactor 1 |
| 10097 | ACTR2; actin related protein 2 |
| 10096 | ACTR3; actin related protein 3 |
| 10552 | ARPC1A; actin related protein 2/3 complex subunit 1A |
| 10095 | ARPC1B; actin related protein 2/3 complex subunit 1B |
| 10109 | ARPC2; actin related protein 2/3 complex subunit 2 |
| 10094 | ARPC3; actin related protein 2/3 complex subunit 3 |
| 10093 | ARPC4; actin related protein 2/3 complex subunit 4 |
| 10092 | ARPC5; actin related protein 2/3 complex subunit 5 |
| 81873 | ARPC5L; actin related protein 2/3 complex subunit 5 like |
|
|---|
| Perturbant |
| K23651 (EspT) | espT; T3SS secreted effector EspT |
|
|---|
| Reference |
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| Authors |
Bulgin R, Arbeloa A, Goulding D, Dougan G, Crepin VF, Raymond B, Frankel G |
|---|
| Title |
The T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals. |
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| Journal |
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| LinkDB |
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