Entry
Name
Definition
TOPBP1+RECQL4 == POLE == GINS -> ORC+CDC6+CDT1 == CDC45+MCM+GINS == POLE+TOPBP1+TICRR+MTBP+RECQL4
Expanded
11073+9401 == 5426+5427+54107+56655 == 9837+51659+64785+84296 -> 4998+4999+23595+5000+5001+23594+990+81620 == 8318+4171+4172+4173+4174+4175+4176+9837+51659+64785+84296 == 5426+5427+54107+56655+11073+90381+27085+9401
Class
Type
Reference
Pathway
Gene
11073 TOPBP1; DNA topoisomerase II binding protein 1
9401 RECQL4; RecQ like helicase 4
5426 POLE; DNA polymerase epsilon, catalytic subunit
5427 POLE2; DNA polymerase epsilon 2, accessory subunit
54107 POLE3; DNA polymerase epsilon 3, accessory subunit
56655 POLE4; DNA polymerase epsilon 4, accessory subunit
9837 GINS1; GINS complex subunit 1
51659 GINS2; GINS complex subunit 2
64785 GINS3; GINS complex subunit 3
84296 GINS4; GINS complex subunit 4
4998 ORC1; origin recognition complex subunit 1
4999 ORC2; origin recognition complex subunit 2
23595 ORC3; origin recognition complex subunit 3
5000 ORC4; origin recognition complex subunit 4
5001 ORC5; origin recognition complex subunit 5
23594 ORC6; origin recognition complex subunit 6
990 CDC6; cell division cycle 6
81620 CDT1; chromatin licensing and DNA replication factor 1
8318 CDC45; cell division cycle 45
4171 MCM2; minichromosome maintenance complex component 2
4172 MCM3; minichromosome maintenance complex component 3
4173 MCM4; minichromosome maintenance complex component 4
4174 MCM5; minichromosome maintenance complex component 5
4175 MCM6; minichromosome maintenance complex component 6
4176 MCM7; minichromosome maintenance complex component 7
90381 TICRR; TOPBP1 interacting checkpoint and replication regulator
27085 MTBP; MDM2 binding protein
Reference
Authors
Tanaka S, Ogawa S
Title
Dimerization of Firing Factors for Replication Origin Activation in Eukaryotes: A Crucial Process for Simultaneous Assembly of Bidirectional Replication Forks?
Journal
Reference
Authors
Gillespie PJ, Blow JJ
Title
DDK: The Outsourced Kinase of Chromosome Maintenance.
Journal
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