KEGG   NETWORK: N01497
Entry
N01497                      Network                                
Name
Condensin loading
Definition
PP2A == Condensin_II -> TOP2A+KIF4A+DNMT3B == Condensin_I
  Expanded
(5515,5516+5518,5519+5525,5526,5527,5528,5529) == (10592+10051+29781+23310+54892) -> 7153+24137+1789 == (10592+10051+23397+9918+64151)
Class
nt06512 Chromosome cohesion and segregation
Type
Reference
Gene
5515  PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516  PPP2CB; protein phosphatase 2 catalytic subunit beta
5518  PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5519  PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5525  PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
5526  PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
5527  PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
5528  PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
5529  PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
10592  SMC2; structural maintenance of chromosomes 2
10051  SMC4; structural maintenance of chromosomes 4
29781  NCAPH2; non-SMC condensin II complex subunit H2
23310  NCAPD3; non-SMC condensin II complex subunit D3
54892  NCAPG2; non-SMC condensin II complex subunit G2
7153  TOP2A; DNA topoisomerase II alpha
24137  KIF4A; kinesin family member 4A
1789  DNMT3B; DNA methyltransferase 3 beta
23397  NCAPH; non-SMC condensin I complex subunit H
9918  NCAPD2; non-SMC condensin I complex subunit D2
64151  NCAPG; non-SMC condensin I complex subunit G
Reference
PMID:26998746
  Authors
Uchiyama S, Fukui K
  Title
Condensin in Chromatid Cohesion and Segregation.
  Journal
Cytogenet Genome Res 147:212-6 (2015)
DOI:10.1159/000444868
Reference
PMID:19915589
  Authors
Takemoto A, Maeshima K, Ikehara T, Yamaguchi K, Murayama A, Imamura S, Imamoto N, Yokoyama S, Hirano T, Watanabe Y, Hanaoka F, Yanagisawa J, Kimura K
  Title
The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A.
  Journal
Nat Struct Mol Biol 16:1302-8 (2009)
DOI:10.1038/nsmb.1708
Reference
PMID:32414923
  Authors
Nielsen CF, Zhang T, Barisic M, Kalitsis P, Hudson DF
  Title
Topoisomerase IIalpha is essential for maintenance of mitotic chromosome structure.
  Journal
Proc Natl Acad Sci U S A 117:12131-12142 (2020)
DOI:10.1073/pnas.2001760117
Reference
PMID:28817632
  Authors
Poonperm R, Takata H, Uchiyama S, Fukui K
  Title
Interdependency and phosphorylation of KIF4 and condensin I are essential for organization of chromosome scaffold.
  Journal
PLoS One 12:e0183298 (2017)
DOI:10.1371/journal.pone.0183298
Reference
PMID:15148359
  Authors
Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD
  Title
Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery.
  Journal
Nucleic Acids Res 32:2716-29 (2004)
DOI:10.1093/nar/gkh589
LinkDB

DBGET integrated database retrieval system