KEGG   Homo sapiens (human): 5525
Entry
5525              CDS       T01001                                 
Symbol
PPP2R5A, B56A, B56alpha, PR61A
Name
(RefSeq) protein phosphatase 2 regulatory subunit B'alpha
  KO
K11584  serine/threonine-protein phosphatase 2A regulatory subunit B'
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04110  Cell cycle
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04382  Cornified envelope formation
hsa04660  T cell receptor signaling pathway
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06166  Human papillomavirus (HPV)
nt06512  Chromosome cohesion and segregation
nt06530  PI3K signaling
nt06537  TCR/BCR signaling
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
N01485  Cohesin dissociation in prophase
N01497  Condensin loading
N01579  CD80/CD86-CTLA4-PP2A signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5525 (PPP2R5A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5525 (PPP2R5A)
   04151 PI3K-Akt signaling pathway
    5525 (PPP2R5A)
   04152 AMPK signaling pathway
    5525 (PPP2R5A)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    5525 (PPP2R5A)
   04114 Oocyte meiosis
    5525 (PPP2R5A)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    5525 (PPP2R5A)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5525 (PPP2R5A)
  09156 Nervous system
   04728 Dopaminergic synapse
    5525 (PPP2R5A)
  09158 Development and regeneration
   04382 Cornified envelope formation
    5525 (PPP2R5A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5525 (PPP2R5A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5525 (PPP2R5A)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5525 (PPP2R5A)
   03036 Chromosome and associated proteins [BR:hsa03036]
    5525 (PPP2R5A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5525 (PPP2R5A)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Protein phosphatase 2A
     5525 (PPP2R5A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5525 (PPP2R5A)
SSDB
Motif
Pfam: B56 ARM_ARMC5
Other DBs
NCBI-GeneID: 5525
NCBI-ProteinID: NP_006234
OMIM: 601643
HGNC: 9309
Ensembl: ENSG00000066027
UniProt: Q15172
Structure
LinkDB
Position
1:212285410..212361853
AA seq 486 aa
MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLK
DATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAY
SDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIA
KRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYET
EHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFL
EKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCV
SSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLK
TLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSIL
SNTSAE
NT seq 1461 nt   +upstreamnt  +downstreamnt
atgtcgtcgtcgtcgccgccggcgggggctgccagcgccgccatctcggcctcggagaaa
gtggacggcttcacccggaaatcggtccgcaaggcgcagaggcagaagcgctcccagggc
tcgtcgcagtttcgcagccagggcagccaggcagagctgcacccgctgccccagctcaaa
gatgccacttcaaatgaacaacaagagcttttctgtcagaagttgcagcagtgttgtata
ctgtttgatttcatggactctgtttcagacttgaagagcaaagaaattaaaagagcaaca
ctgaatgaactggttgagtatgtttcaactaatcgtggtgtaattgttgaatcagcgtat
tctgatatagtaaaaatgatcagtgctaacatcttccgtacacttcctccaagtgataat
ccagattttgatccagaagaggatgaacccacgcttgaggcctcttggcctcacatacag
ttggtatatgaattcttcttgagatttttggagagccctgatttccagcctagcattgca
aaacgatacattgatcagaaattcgtacaacagctcctggagctttttgatagtgaagat
cccagagaacgtgacttcctgaagactgttctgcaccgaatttatgggaaatttcttgga
ttaagagcattcatcagaaaacaaattaacaacattttcctcaggtttatatatgaaaca
gaacatttcaatggtgttgctgaacttcttgaaatattaggaagtattatcaatggcttt
gcattgccactgaaagcagaacataaacaatttctaatgaaggttcttattcctatgcat
actgcaaaaggattagctttgtttcatgctcagctagcatattgtgttgtacagttcctg
gagaaagatacaacactaacagagccagtgatcagaggactgctgaaattttggccaaaa
acctgcagtcagaaagaggtgatgtttttaggagaaattgaagaaatcttagatgtcatt
gaaccaacacagttcaaaaaaattgaagagccacttttcaagcagatatccaagtgtgta
tccagttctcattttcaggttgcagaaagggcattgtacttctggaataacgaatatatt
cttagtttgattgaggagaacattgataaaattctgccaattatgtttgccagtttgtac
aaaatttccaaagaacactggaatccgaccattgtagcactggtatacaatgtgctgaaa
accctaatggaaatgaatggcaagcttttcgatgaccttactagctcatacaaagctgaa
agacagagagagaaaaagaaggaattggaacgtgaagaattatggaaaaaattagaggag
ctaaagctaaagaaagctctagaaaaacagaatagtgcttacaacatgcacagtattctc
agcaatacaagtgccgaataa

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