| Entry |
|
|---|
| Name |
Serotonin-HTR1/5-GNAI/O signaling pathway
|
|---|
| Definition |
Serotonin -> (HTR1,HTR5A) -> (GNAI,GNAO) -| ADCY |
|---|
| Expanded |
C00780 -> (3350,3351,3352,3354,3355,3361) -> ((2770,2771,2773),2775) -| (107,108,109,196883,111,112,113,114,115) |
|---|
| Class |
nt06544 Neuroactive ligand signaling
|
|---|
| Type |
Reference
|
|---|
| Pathway |
|
|---|
| Gene |
| 3350 | HTR1A; 5-hydroxytryptamine receptor 1A |
| 3351 | HTR1B; 5-hydroxytryptamine receptor 1B |
| 3352 | HTR1D; 5-hydroxytryptamine receptor 1D |
| 3354 | HTR1E; 5-hydroxytryptamine receptor 1E |
| 3355 | HTR1F; 5-hydroxytryptamine receptor 1F |
| 3361 | HTR5A; 5-hydroxytryptamine receptor 5A |
| 2770 | GNAI1; G protein subunit alpha i1 |
| 2771 | GNAI2; G protein subunit alpha i2 |
| 2773 | GNAI3; G protein subunit alpha i3 |
| 2775 | GNAO1; G protein subunit alpha o1 |
| 107 | ADCY1; adenylate cyclase 1 |
| 108 | ADCY2; adenylate cyclase 2 |
| 109 | ADCY3; adenylate cyclase 3 |
| 196883 | ADCY4; adenylate cyclase 4 |
| 111 | ADCY5; adenylate cyclase 5 |
| 112 | ADCY6; adenylate cyclase 6 |
| 113 | ADCY7; adenylate cyclase 7 |
| 114 | ADCY8; adenylate cyclase 8 |
| 115 | ADCY9; adenylate cyclase 9 |
|
|---|
| Metabolite |
|
|---|
| Reference |
|
|---|
| Authors |
Berumen LC, Rodriguez A, Miledi R, Garcia-Alcocer G |
|---|
| Title |
Serotonin receptors in hippocampus. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Pourhamzeh M, Moravej FG, Arabi M, Shahriari E, Mehrabi S, Ward R, Ahadi R, Joghataei MT |
|---|
| Title |
The Roles of Serotonin in Neuropsychiatric Disorders. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Millan MJ, Marin P, Bockaert J, Mannoury la Cour C |
|---|
| Title |
Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
