KEGG   REACTION: R01171
Entry
R01171                      Reaction                               
Name
butanoyl-CoA:NAD+ trans-2-oxidoreductase
Definition
Butanoyl-CoA + NAD+ <=> Crotonoyl-CoA + NADH + H+
Equation
C00136 + C00003 <=> C00877 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00076  C00136_C00877
Enzyme
1.3.1.44
Pathway
rn00310  Lysine degradation
rn00650  Butanoate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.44
     R01171  Butanoyl-CoA + NAD+ <=> Crotonoyl-CoA + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.3.1.44
   R00384  Acyl-CoA <=> trans-2,3-Dehydroacyl-CoA
    R01171  Butanoyl-CoA <=> Crotonoyl-CoA
Orthology
K00209  enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]
Other DBs
RHEA: 52575
LinkDB

KEGG   RCLASS: RC00076
Entry
RC00076                     RClass                                 
Definition
C1b-C2b:*-*:C1a+C1b-C1a+C2b
C1b-C2b:*-*:C1b+C5a-C2b+C5a
Reactant pair
C00136_C00877    C04246_C05745
Related class
Reaction
R01171 R01175 R04429 R04430 R09738 R11675
Enzyme
1.3.1.9         1.3.1.10        1.3.1.39        1.3.1.44        
1.3.1.86        1.3.1.104       1.3.1.109       1.3.1.-         
1.3.3.6         1.3.8.1         1.3.8.7         1.3.99.-        
2.3.1.85        2.3.1.86        2.3.1.-
Pathway
rn00061  Fatty acid biosynthesis
rn00071  Fatty acid degradation
rn00310  Lysine degradation
rn00650  Butanoate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01212  Fatty acid metabolism
RModule
RM018  Beta oxidation in acyl-CoA degradation
RM019  Acyl-CoA conversion via dicarboxylate semialdehyde
RM020  Fatty acid synthesis using acetyl-CoA (reversal of RM018)
RM021  Fatty acid synthesis using malonyl-CoA
Orthology
K00208  enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
K00209  enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]
K00232  acyl-CoA oxidase [EC:1.3.3.6]
K00248  butyryl-CoA dehydrogenase [EC:1.3.8.1]
K00249  acyl-CoA dehydrogenase [EC:1.3.8.7]
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
K00668  fatty acid synthase subunit beta, fungi type [EC:2.3.1.86]
K02371  enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
K06445  acyl-CoA dehydrogenase [EC:1.3.99.-]
K07512  mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase [EC:1.3.1.- 1.3.1.38]
K09478  short-chain 2-methylacyl-CoA dehydrogenase [EC:1.3.8.5]
K10780  enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.104]
K11533  fatty acid synthase, bacteria type [EC:2.3.1.-]
K17829  crotonyl-CoA reductase [EC:1.3.1.86]

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