KEGG   REACTION: R01594
Entry
R01594                      Reaction                               
Name
arachidonate:oxygen 8-oxidoreductase
Definition
Arachidonate + Oxygen <=> 8(R)-HPETE
Equation
C00219 + C00007 <=> C04822
Reaction class
RC00561  C00219_C04822
Enzyme
1.13.11.40
Pathway
rn00590  Arachidonic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.40
     R01594  Arachidonate + Oxygen <=> 8(R)-HPETE
Orthology
K26082  arachidonate 8-lipoxygenase / allene oxide synthase [EC:1.13.11.40 4.2.1.-]
Other DBs
RHEA: 14988
LinkDB

KEGG   RCLASS: RC00561
Entry
RC00561                     RClass                                 
Definition
C1b-C2b:*-*:C2b+C2b-C2b+C2b
C2b-C1c:*-O2a:C1b+C2b-C1b+C2b
Reactant pair
C00219_C04822    C00219_C05356    C00219_C05965
C00219_C05966    C00219_C14812    C00219_C14820
C00219_C14821    C00219_C14823    C01595_C04717
C01595_C14827    C04785_C06427    C06427_C16321
C06427_C19936
Related class
Reaction
R01593 R01594 R01595 R01596 R03626 R07038 R07047 R07049
R07053 R07057 R07864 R07869 R09810
Enzyme
1.13.11.12      1.13.11.31      1.13.11.33      1.13.11.34      
1.13.11.40      1.13.11.58      1.13.11.61      1.13.11.-
Pathway
rn00590  Arachidonic acid metabolism
rn00591  Linoleic acid metabolism
rn00592  alpha-Linolenic acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00454  lipoxygenase [EC:1.13.11.12]
K00458  arachidonate 12-lipoxygenase [EC:1.13.11.31]
K00460  arachidonate 15-lipoxygenase [EC:1.13.11.33]
K00461  arachidonate 5-lipoxygenase [EC:1.13.11.34]
K08021  arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
K08022  arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K15718  linoleate 9S-lipoxygenase [EC:1.13.11.58]
K19246  arachidonate 15-lipoxygenase [EC:1.13.11.33]
K26082  arachidonate 8-lipoxygenase / allene oxide synthase [EC:1.13.11.40 4.2.1.-]

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