KEGG   REACTION: R04749
Entry
R04749                      Reaction                               
Name
(S)-hydroxyhexanoyl-CoA hydro-lyase
Definition
(S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA + H2O
Equation
C05268 <=> C05271 + C00001
Reaction class
RC01095  C05268_C05271
Enzyme
4.2.1.17        4.2.1.74
Pathway
rn00062  Fatty acid elongation
rn00071  Fatty acid degradation
rn01100  Metabolic pathways
rn01212  Fatty acid metabolism
Module
M00085  Fatty acid elongation in mitochondria
M00087  beta-Oxidation
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17
     R04749  (S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA + H2O
    4.2.1.74
     R04749  (S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA + H2O
IUBMB reaction hierarchy [BR:br08202]
 4. Lyase reactions
  4.2.1.17
   R02685  (3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA
    R04749  (S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA
  4.2.1.74
   R02685  (3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA
    R04749  (S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA
Orthology
K01692  enoyl-CoA hydratase [EC:4.2.1.17]
K01782  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01825  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
K07511  enoyl-CoA hydratase [EC:4.2.1.17]
K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07515  enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K10527  enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35 1.1.1.211]
Other DBs
RHEA: 30550
LinkDB

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