KEGG   REACTION: R06774
Entry
R06774                      Reaction                               
Definition
Novclobiocin 105 + S-Adenosyl-L-methionine <=> Novclobiocin 104 + S-Adenosyl-L-homocysteine
Equation
C12472 + C00019 <=> C12473 + C00021
Comment
O-methyltransferase, CloP
Reaction class
RC00003  C00019_C00021
RC00466  C12472_C12473
Pathway
rn00401  Novobiocin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K12712  demethyldecarbamoylnovobiocin O-methyltransferase [EC:2.1.1.285]
LinkDB

KEGG   RCLASS: RC00466
Entry
RC00466                     RClass                                 
Definition
O1a-O2a:*-C1a:C1y-C1y
Reactant pair
C00137_C03659    C00137_C03660    C00137_C06352
C00744_C01457    C00744_C02400    C01977_C04545
C02079_C07349    C02339_C04802    C03319_C21350
C03866_C04459    C04802_C20862    C11927_C21071
C11955_C11956    C11963_C11964    C11971_C11972
C11979_C11980    C11991_C11992    C12382_C12383
C12472_C12473    C12475_C12476    C15681_C15682
C15681_C18846    C19700_C19701    C20974_C20975
C20975_C20976    C20976_C20977
Related class
Reaction
R01188 R01189 R01190 R02858 R02859 R02917 R03922 R04332
R05757 R06456 R06476 R06477 R06478 R06479 R06715 R06771
R06774 R09569 R09822 R09823 R10812 R10956 R10957 R10958
R11041 R11469
Enzyme
2.1.1.34        2.1.1.39        2.1.1.40        2.1.1.57        
2.1.1.101       2.1.1.102       2.1.1.112       2.1.1.129       
2.1.1.139       2.1.1.164       2.1.1.237       2.1.1.238       
2.1.1.239       2.1.1.285       2.1.1.296       2.1.1.305       
2.1.1.306       2.1.1.307       2.1.1.-
Pathway
rn00401  Novobiocin biosynthesis
rn00404  Staurosporine biosynthesis
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
rn00523  Polyketide sugar unit biosynthesis
rn00562  Inositol phosphate metabolism
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Orthology
K12712  demethyldecarbamoylnovobiocin O-methyltransferase [EC:2.1.1.285]
K13320  L-olivosyl-oleandolide 3-O-methyltransferase [EC:2.1.1.239]
K14374  avermectin B 5-O-methyltransferase [EC:2.1.1.-]
K14589  cap1 methyltransferase [EC:2.1.1.57]
K14590  cap2 methyltransferase [EC:2.1.1.296]
K15959  O-methyltransferase [EC:2.1.1.-]
K15995  demethylmacrocin O-methyltransferase [EC:2.1.1.102]
K15996  macrocin O-methyltransferase [EC:2.1.1.101]
K18776  cap2 methyltransferase [EC:2.1.1.296]
K19567  8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase [EC:2.1.1.305]
K19568  8-demethyl-8-(2-methoxy-alpha-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase [EC:2.1.1.306]
K19569  8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase [EC:2.1.1.307]
K19856  3-O-methyltransferase [EC:2.1.1.-]
K19889  demethylrebeccamycin-D-glucose O-methyltransferase [EC:2.1.1.164]
K20082  O-methyltransferase StaMB [EC:2.1.1.139]
K21325  dTDP-rhamnose C3-O-methyltransferase [EC:2.1.1.-]
K21539  mycinamicin III 3''-O-methyltransferase [EC:2.1.1.237]
K21540  mycinamicin VI 2''-O-methyltransferase [EC:2.1.1.238]

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