KEGG   REACTION: R07046
Entry
R07046                      Reaction                               
Definition
Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19(S)-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00219 + C03024 + C00007 <=> C14749 + C03161 + C00001
Comment
CYP2E1, CYP2J9, CYP2U1, CYP1A2, CYP2C19, CYP3A5, CYP4A11, CYP4F8
Reaction class
RC01710  C00219_C14749
Enzyme
1.14.14.1       1.14.14.80      1.14.14.-
Pathway
rn00590  Arachidonic acid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R07046  Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19(S)-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.80
     R07046  Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19(S)-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.-
     R07046  Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19(S)-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07418  cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K07422  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K07425  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K17721  cytochrome P450 family 2 subfamily C19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
K17728  cytochrome P450 family 4 subfamily F8 [EC:1.14.14.1]
LinkDB

KEGG   RCLASS: RC01710
Entry
RC01710                     RClass                                 
Definition
C1b-C1c:*-O1a:C1a+C1b-C1a+C1b
Reactant pair
C00219_C14749    C07185_C16649    C20499_C20500
C20499_C20501
Related class
Reaction
R07046 R08325 R10317 R10318
Enzyme
1.14.14.1       1.14.14.80      1.14.14.116     1.14.14.-
Pathway
rn00254  Aflatoxin biosynthesis
rn00590  Arachidonic acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07418  cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K07422  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K07425  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K17645  averantin hydroxylase [EC:1.14.14.116]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17709  cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K17721  cytochrome P450 family 2 subfamily C19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
K17728  cytochrome P450 family 4 subfamily F8 [EC:1.14.14.1]

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