KEGG REACTION: R07168

REACTION: R07168

Entry

R07168                      Reaction

Name

5-methyltetrahydrofolate:NAD+ oxidoreductase

Definition

5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+

Equation

C00440 + C00003 <=> C00143 + C00004 + C00080

Reaction class

RC00001

C00003_C00004

RC00081

C00143_C00440

Enzyme

1.5.1.20 1.5.1.54

Pathway

rn00670

One carbon pool by folate

rn00720

Other carbon fixation pathways

rn01100

Metabolic pathways

rn01120

Microbial metabolism in diverse environments

rn01200

Carbon metabolism

Module

M00377

Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.20
     R07168  5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
    1.5.1.54
     R07168  5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
Overall reaction [br08210.html]
Carbon fixation
  R07168

Orthology

K00297

methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]

K24042

methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]

K25009

methylenetetrahydrofolate reductase [NAD(P)H] [EC:1.5.1.20]

Other DBs

RHEA:

19824

LinkDB

RCLASS: RC00081