REACTION: R08640
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Entry
R08640 Reaction
Name
acetyl-CoA:8-methylthio-2-oxooctanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
Definition
2-Oxo-8-methylthiooctanoic acid + Acetyl-CoA + H2O <=> 2-(6'-Methylthio)hexylmalic acid + CoA
Equation
C17224
+
C00024
+
C00001
<=>
C17226
+
C00010
Reaction class
RC00004
C00010_C00024
RC00067
C17224_C17226
Enzyme
2.3.3.17
Pathway
rn00966
Glucosinolate biosynthesis
rn01210
2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.17
R08640 2-Oxo-8-methylthiooctanoic acid + Acetyl-CoA + H2O <=> 2-(6'-Methylthio)hexylmalic acid + CoA
BRITE hierarchy
Orthology
K15742
methylthioalkylmalate synthase 3 [EC:
2.3.3.17
]
LinkDB
All DBs
RCLASS: RC00067
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Entry
RC00067 RClass
Definition
C1d-C5a:C1b-*:C1b+C6a+O1a-C1b+C6a+O5a
Reactant pair
C00026_C01251
C00036_C00158
C00036_C00566
C00036_C04115
C00109_C02488
C00166_C20653
C00322_C16583
C01180_C17210
C02798_C21613
C05994_C06255
C06368_C17947
C16588_C16598
C17211_C17214
C17216_C17218
C17220_C17222
C17224_C17226
C17228_C17230
Related class
DB search
Reaction
R00271
R00350
R00351
R00352
R00354
R00362
R00998
R05063
R08331
R08332
R08619
R08623
R08627
R08631
R08640
R08644
R08870
R10500
R11708
Enzyme
2.3.3.1
2.3.3.3
2.3.3.5
2.3.3.6
2.3.3.8
2.3.3.14
2.3.3.16
2.3.3.17
2.3.3.18
2.3.3.19
2.3.3.-
4.1.3.6
4.1.3.17
4.1.3.34
4.1.3.-
Pathway
rn00020
Citrate cycle (TCA cycle)
rn00300
Lysine biosynthesis
rn00362
Benzoate degradation
rn00400
Phenylalanine, tyrosine and tryptophan biosynthesis
rn00440
Phosphonate and phosphinate metabolism
rn00630
Glyoxylate and dicarboxylate metabolism
rn00680
Methane metabolism
rn00720
Other carbon fixation pathways
rn00966
Glucosinolate biosynthesis
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
rn01200
Carbon metabolism
rn01210
2-Oxocarboxylic acid metabolism
rn01230
Biosynthesis of amino acids
rn01240
Biosynthesis of cofactors
RModule
RM001
2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K01643
citrate lyase subunit alpha / citrate CoA-transferase [EC:
2.8.3.10
]
K01644
citrate lyase subunit beta / citryl-CoA lyase [EC:
4.1.3.34
]
K01646
citrate lyase subunit gamma (acyl carrier protein)
K01647
citrate synthase [EC:
2.3.3.1
]
K01648
ATP citrate (pro-S)-lyase [EC:
2.3.3.8
]
K01655
homocitrate synthase [EC:
2.3.3.14
]
K01659
2-methylcitrate synthase [EC:
2.3.3.5
]
K02594
homocitrate synthase NifV [EC:
2.3.3.14
]
K05942
citrate (Re)-synthase [EC:
2.3.3.3
]
K10218
4-hydroxy-4-methyl-2-oxoglutarate aldolase [EC:
4.1.3.17
]
K10977
methanogen homocitrate synthase [EC:
2.3.3.14
2.3.3.-]
K12910
2-phosphinomethylmalate synthase [EC:
2.3.3.18
]
K15230
ATP-citrate lyase alpha-subunit [EC:
2.3.3.8
]
K15231
ATP-citrate lyase beta-subunit [EC:
2.3.3.8
]
K15234
citryl-CoA lyase [EC:
4.1.3.34
]
K15741
methylthioalkylmalate synthase 1 [EC:
2.3.3.17
]
K15742
methylthioalkylmalate synthase 3 [EC:
2.3.3.17
]
K17748
benzylmalate synthase [EC:2.3.3.-]
K21934
2-phosphonomethylmalate synthase [EC:
2.3.3.19
]
K27797
2-methylcitrate synthase [EC:
2.3.3.5
]
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integrated database retrieval system