KEGG   PATHWAY: avn00622
Entry
avn00622                    Pathway                                
Name
Xylene degradation - Azotobacter vinelandii DJ
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
avn00622  Xylene degradation
avn00622

Module
avn_M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:avn00622]
avn_M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:avn00622]
Other DBs
GO: 0042184
UMBBD: mxy oxy pxy pcy tol
Organism
Azotobacter vinelandii DJ [GN:avn]
Gene
Avin_08590  benA; Benzoate-1,2-dioxygenase oxygenase component, alpha subunit [KO:K05549] [EC:1.14.12.10 1.14.12.-]
Avin_08600  benB; benzoate-1,2-dioxygenase oxygenase component, beta subunit [KO:K05550] [EC:1.14.12.10 1.14.12.-]
Avin_08610  benC; Benzoate 1,2-Dioxygenase Reductase [KO:K05784] [EC:1.18.1.-]
Avin_08620  benD; cis-1,2-dihydroxycyclohexa-3,4-diene carboxylate dehydrogenase [KO:K05783] [EC:1.3.1.25 1.3.1.-]
Avin_08720  xylE; Catechol 2,3 dioxygenase, XylE [KO:K00446] [EC:1.13.11.2]
Avin_30770  lapB; catechol 2,3-dioxygenase, LapB [KO:K00446] [EC:1.13.11.2]
Avin_08800  dmpB; Extradiol ring-cleavage dioxygenase [KO:K00446] [EC:1.13.11.2]
Avin_08730  xylG; 2-hydroxymuconic semi-aldehyde dehydrogenase [KO:K10217] [EC:1.2.1.32 1.2.1.85]
Avin_30620  lapC; 2-hydroxymuconic semialdehyde dehydrogenase; LapC [KO:K10217] [EC:1.2.1.32 1.2.1.85]
Avin_45080  4-oxalocrotonate tautomerase [KO:K01821] [EC:5.3.2.6]
Avin_08790  dmpI; 4-oxalocrotonate tautomerase [KO:K01821] [EC:5.3.2.6]
Avin_08680  xylI; 4-oxalocrotonate decarboxylase.XylI [KO:K01617] [EC:4.1.1.77]
Avin_30600  lapH; 4-oxalocrotonate decarboxylase; LapH [KO:K01617] [EC:4.1.1.77]
Avin_08670  xylJ; 4-oxo-4-pentenoate hydratase, XylJ [KO:K18364] [EC:4.2.1.80 4.2.1.132]
Avin_30610  lapE; 2-Hydroxypent-2,4-dienoate hydratase; LapE [KO:K18364] [EC:4.2.1.80 4.2.1.132]
Avin_30570  lapG; 4-hydroxy-2-oxovalerate aldolase; LapG [KO:K18365] [EC:4.1.3.39 4.1.3.43]
Avin_30580  lapF; Acetaldehyde dehydrogenase (acetylating); LapF [KO:K18366] [EC:1.2.1.10 1.2.1.87]
Avin_15110  mhpD; 4-oxalocrotonate decarboxylase [KO:K02554] [EC:4.2.1.80]
Avin_42120  4-hydroxy-2-oxovalerate aldolase [KO:K01666] [EC:4.1.3.39]
Avin_08740  xylK; 4-hydroxy-2-oxovalerate aldolase, XylK [KO:K01666] [EC:4.1.3.39]
Avin_15130  mphE; 4-hydroxy-2-ketovalerate aldolase [KO:K01666] [EC:4.1.3.39]
Avin_42130  Acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
Avin_08700  xylQ; acetaldehyde dehydrogenase, XylQ [KO:K04073] [EC:1.2.1.10]
Avin_15120  mhpF; Acetaldehyde dehydrogenase (acylating) [KO:K04073] [EC:1.2.1.10]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00084  Acetaldehyde
C00100  Propanoyl-CoA
C00479  Propanal
C00596  2-Hydroxy-2,4-pentadienoate
C01454  Toluate
C02923  2,3-Dihydroxytoluene
C03589  4-Hydroxy-2-oxopentanoate
C06210  2-Hydroxy-6-keto-2,4-heptadienoate
C06575  p-Cymene
C06576  p-Cumic alcohol
C06577  4-Isopropylbenzaldehyde
C06578  p-Cumate
C06579  cis-2,3-Dihydroxy-2,3-dihydro-p-cumate
C06580  2,3-Dihydroxy-p-cumate
C06581  2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
C06582  2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate
C06720  1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate
C06729  cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
C06730  4-Methylcatechol
C06731  1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate
C06756  p-Xylene
C06757  4-Methylbenzyl alcohol
C06758  p-Tolualdehyde
C06760  2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
C06762  4-Hydroxy-2-oxohexanoic acid
C07208  m-Xylene
C07209  3-Methylbenzaldehyde
C07211  m-Methylbenzoate
C07212  o-Xylene
C07213  2-Methylbenzyl alcohol
C07214  2-Methylbenzaldehyde
C07215  o-Toluate
C07216  3-Methylbenzyl alcohol
C07478  2-Hydroxy-5-methyl-cis,cis-muconate
C07479  2-Oxo-5-methyl-cis-muconate
C11354  2-Hydroxy-cis-hex-2,4-dienoate
Reference
PMID:11375157
  Authors
Haddad S, Eby DM, Neidle EL.
  Title
Cloning and expression of the benzoate dioxygenase genes from Rhodococcus sp. strain 19070.
  Journal
Appl Environ Microbiol 67:2507-14 (2001)
DOI:10.1128/AEM.67.6.2507-2514.2001
Reference
PMID:7768806
  Authors
Kim E, Zylstra GJ
  Title
Molecular and biochemical characterization of two meta-cleavage dioxygenases involved in biphenyl and m-xylene degradation by Beijerinckia sp. strain B1.
  Journal
J Bacteriol 177:3095-103 (1995)
DOI:10.1128/JB.177.11.3095-3103.1995
Reference
PMID:15127183
  Authors
Morasch B, Schink B, Tebbe CC, Meckenstock RU
  Title
Degradation of o-xylene and m-xylene by a novel sulfate-reducer belonging to the genus Desulfotomaculum.
  Journal
Arch Microbiol 181:407-17 (2004)
DOI:10.1007/s00203-004-0672-6
Reference
PMID:9150211
  Authors
Eaton RW.
  Title
p-Cymene catabolic pathway in Pseudomonas putida F1: cloning and characterization of DNA encoding conversion of p-cymene to p-cumate.
  Journal
J Bacteriol 179:3171-80 (1997)
DOI:10.1128/JB.179.10.3171-3180.1997
Reference
PMID:8631713
  Authors
Eaton RW.
  Title
p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon.
  Journal
J Bacteriol 178:1351-62 (1996)
DOI:10.1128/JB.178.5.1351-1362.1996
Related
pathway
avn00010  Glycolysis / Gluconeogenesis
avn00020  Citrate cycle (TCA cycle)
avn00623  Toluene degradation
avn00640  Propanoate metabolism
KO pathway
ko00622   
LinkDB

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