KEGG   PATHWAY: bmk00630
Entry
bmk00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia multivorans DDS 15A-1
Class
Metabolism; Carbohydrate metabolism
Pathway map
bmk00630  Glyoxylate and dicarboxylate metabolism
bmk00630

Module
bmk_M00012  Glyoxylate cycle [PATH:bmk00630]
bmk_M00621  Glycine cleavage system [PATH:bmk00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia multivorans DDS 15A-1 [GN:bmk]
Gene
DM80_2928  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
DM80_2779  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM80_328  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM80_5037  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM80_5559  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM80_6426  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM80_4569  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
DM80_2924  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
DM80_3851  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DM80_2428  merR regulatory family protein [KO:K01647] [EC:2.3.3.1]
DM80_3844  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DM80_1414  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
DM80_3855  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
DM80_4326  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
DM80_3237  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM80_2161  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM80_5561  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM80_5580  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM80_3122  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM80_6204  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DM80_3238  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DM80_6342  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
DM80_2162  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DM80_935  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
DM80_936  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
DM80_937  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
DM80_340  catalase family protein [KO:K03781] [EC:1.11.1.6]
DM80_1677  catalase family protein [KO:K03781] [EC:1.11.1.6]
DM80_1965  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DM80_3281  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DM80_537  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DM80_1141  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
DM80_5112  haloacid dehalogenase-like hydrolase family protein [KO:K01091] [EC:3.1.3.18]
DM80_528  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
DM80_1930  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DM80_2802  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DM80_2818  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
DM80_5104  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DM80_4935  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
DM80_883  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
DM80_1551  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
DM80_1549  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
DM80_2832  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM80_149  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM80_1550  gcvH; glycine cleavage system H protein [KO:K02437]
DM80_3149  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DM80_3148  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DM80_3147  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DM80_3096  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
DM80_4406  aldA; lactaldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
DM80_4530  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DM80_4200  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DM80_6474  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DM80_1010  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DM80_5638  fdh; NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
DM80_663  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
DM80_3801  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DM80_3802  molybdopterin oxidoreductase Fe4S4 domain protein [KO:K00123] [EC:1.17.1.9]
DM80_662  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DM80_661  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
DM80_3800  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
DM80_660  thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]
DM80_3799  formate dehydrogenase, gamma subunit [KO:K00127]
DM80_2388  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
DM80_4953  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM80_2152  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM80_2800  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bmk00010  Glycolysis / Gluconeogenesis
bmk00020  Citrate cycle (TCA cycle)
bmk00030  Pentose phosphate pathway
bmk00053  Ascorbate and aldarate metabolism
bmk00071  Fatty acid degradation
bmk00230  Purine metabolism
bmk00250  Alanine, aspartate and glutamate metabolism
bmk00260  Glycine, serine and threonine metabolism
bmk00620  Pyruvate metabolism
bmk00710  Carbon fixation by Calvin cycle
bmk00750  Vitamin B6 metabolism
bmk00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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