KEGG   PATHWAY: bxh00520
Entry
bxh00520                    Pathway                                
Name
Amino sugar and nucleotide sugar metabolism - Bacillus amyloliquefaciens XH7
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
bxh00520  Amino sugar and nucleotide sugar metabolism
bxh00520

Module
bxh_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:bxh00520]
bxh_M00554  UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:bxh00520]
bxh_M00909  UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:bxh00520]
bxh_M00995  UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:bxh00520]
Other DBs
GO: 0006040 0009225
Organism
Bacillus amyloliquefaciens XH7 [GN:bxh]
Gene
BAXH7_00055  glmU; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase [KO:K04042] [EC:2.7.7.23 2.3.1.157]
BAXH7_00174  ybbD; putative beta-hexosaminidase, putative lipoprotein [KO:K01207] [EC:3.2.1.52]
BAXH7_00178  murQ; N-acetylmuramic acid-6-phosphate etherase [KO:K07106] [EC:4.2.1.126]
BAXH7_00185  glmM; phosphoglucosamine mutase [KO:K03431] [EC:5.4.2.10]
BAXH7_00188  glmS; glucosamine--fructose-6-phosphate [KO:K00820] [EC:2.6.1.16]
BAXH7_00595  ydjE; putative sugar kinase (ribokinase family) [KO:K00847] [EC:2.7.1.4]
BAXH7_00694  yfnH; putative sugar-phosphate cytidylyltransferase [KO:K00978] [EC:2.7.7.33]
BAXH7_00738  nagP; phosphotransferase system (PTS) N-acetylglucosamine-specific enzyme IICB component [KO:K02804] [EC:2.7.1.193]
BAXH7_00907  yhxB; putative phosphomannomutase [KO:K01835] [EC:5.4.2.2]
BAXH7_01225  ypqE; putative phosphotransferase system enzyme IIA component [KO:K02777] [EC:2.7.1.-]
BAXH7_01604  yngB; putative UTP-sugar-phosphate uridylyltransferase [KO:K00963] [EC:2.7.7.9]
BAXH7_01623  xynD; endo-1,4-beta-xylanase [KO:K15921] [EC:3.2.1.55]
BAXH7_01702  xynB; xylan beta-1,4-xylosidase [KO:K01198] [EC:3.2.1.37]
BAXH7_01943  murB; UDP-N-acetylenolpyruvoylglucosamine reductase [KO:K00075] [EC:1.3.1.98]
BAXH7_02081  ptsG; phosphotransferase system (PTS) glucose-specificenzyme IICBA component [KO:K20118] [EC:2.7.1.199]
BAXH7_02606  glcK; glucose kinase [KO:K25026]
BAXH7_02714  manA; mannose-6-phosphate isomerase [KO:K01809] [EC:5.3.1.8]
BAXH7_02866  xsa; alpha-N-arabinofuranosidase II [KO:K01209] [EC:3.2.1.55]
BAXH7_02890  abfA; alpha-L-arabinofuranosidase I [KO:K01209] [EC:3.2.1.55]
BAXH7_03183  pgi; glucose-6-phosphate isomerase [KO:K01810] [EC:5.3.1.9]
BAXH7_03372  csn; chitosanase [KO:K01233] [EC:3.2.1.132]
BAXH7_03627  nagA; N-acetylglucosamine-6-phosphate deacetylase [KO:K01443] [EC:3.5.1.25]
BAXH7_03628  nagB; N-acetylglucosamine-6-phosphate isomerase [KO:K02564] [EC:3.5.99.6]
BAXH7_03682  tuaD; UDP-glucose 6-dehydrogenase [KO:K00012] [EC:1.1.1.22]
BAXH7_03690  mnaA; UDP-N-acetylmannosamine 2-epimerase [KO:K01791] [EC:5.1.3.14]
BAXH7_03692  gtaB; UTP-glucose-1-phosphate uridylyltransferase [KO:K00963] [EC:2.7.7.9]
BAXH7_03701  pmi; mannose-6-phosphate isomerase [KO:K01809] [EC:5.3.1.8]
BAXH7_03757  ywqF; UDP-glucose dehydrogenase [KO:K00012] [EC:1.1.1.22]
BAXH7_03811  murAA; UDP-N-acetylglucosamine [KO:K00790] [EC:2.5.1.7]
BAXH7_03848  murAB; UDP-N-acetylglucosamine [KO:K00790] [EC:2.5.1.7]
BAXH7_03922  spsI; putative dTDP-glucose pyrophosphorylase [KO:K00973] [EC:2.7.7.24]
BAXH7_03961  galT; galactose-1-phosphate uridylyltransferase [KO:K00965] [EC:2.7.7.12]
BAXH7_03962  galK; galactokinase [KO:K00849] [EC:2.7.1.6]
BAXH7_04016  ydhR; putative fructokinase [KO:K00847] [EC:2.7.1.4]
BAXH7_04017  ydhS; putative mannose-6-phosphate isomerase [KO:K01809] [EC:5.3.1.8]
BAXH7_04033  galE; UDP-glucose 4-epimerase [KO:K01784] [EC:5.1.3.2]
Compound
C00029  UDP-glucose
C00031  D-Glucose
C00043  UDP-N-acetyl-alpha-D-glucosamine
C00052  UDP-alpha-D-galactose
C00085  D-Fructose 6-phosphate
C00095  D-Fructose
C00096  GDP-mannose
C00103  D-Glucose 1-phosphate
C00140  N-Acetyl-D-glucosamine
C00159  D-Mannose
C00167  UDP-glucuronate
C00181  D-Xylose
C00190  UDP-D-xylose
C00191  D-Glucuronate
C00203  UDP-N-acetyl-D-galactosamine
C00216  D-Arabinose
C00259  L-Arabinose
C00267  alpha-D-Glucose
C00275  D-Mannose 6-phosphate
C00325  GDP-L-fucose
C00329  D-Glucosamine
C00333  D-Galacturonate
C00352  D-Glucosamine 6-phosphate
C00357  N-Acetyl-D-glucosamine 6-phosphate
C00394  GDP-glucose
C00446  alpha-D-Galactose 1-phosphate
C00461  Chitin
C00498  ADP-glucose
C00501  CDP-glucose
C00617  UDP-D-galacturonate
C00636  D-Mannose 1-phosphate
C00645  N-Acetyl-D-mannosamine
C00668  alpha-D-Glucose 6-phosphate
C00714  Pectin
C00734  Chitosan
C00842  dTDP-glucose
C00935  UDP-L-arabinose
C00976  GDP-D-mannuronate
C00984  alpha-D-Galactose
C01019  L-Fucose
C01050  UDP-N-acetylmuramate
C01132  N-Acetyl-D-galactosamine
C01170  UDP-N-acetyl-D-mannosamine
C01623  UDP-apiose
C01674  Chitobiose
C02262  D-Galactosamine
C02280  GDP-L-galactose
C02352  1,4-beta-D-Xylan
C02474  Arabinan
C02713  N-Acetylmuramate
C02985  L-Fucose 1-phosphate
C03733  UDP-alpha-D-galactofuranose
C03737  alpha-D-Xylose 1-phosphate
C03906  beta-L-Arabinose 1-phosphate
C04037  1-Phospho-alpha-D-galacturonate
C04257  N-Acetyl-D-mannosamine 6-phosphate
C04501  N-Acetyl-alpha-D-glucosamine 1-phosphate
C04631  UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine
C05385  D-Glucuronate 1-phosphate
C06023  D-Glucosaminide
C06156  alpha-D-Glucosamine 1-phosphate
C06376  N-Acetyl-D-galactosamine 6-phosphate
C06377  D-Galactosamine 6-phosphate
C11521  UDP-6-sulfoquinovose
C15925  GDP-L-gulose
C16183  alpha-D-Arabinopyranose 1-phosphate
C16698  N-Acetylmuramic acid 6-phosphate
C17269  GDP-D-arabinopyranose
C18060  N-Acetyl-alpha-D-galactosamine 1-phosphate
C18094  UDP-L-arabinofuranose
C19769  1,6-Anhydro-N-acetyl-beta-muramate
C21027  N-Acetylmuramic acid alpha-1-phosphate
C22029  alpha-D-Galactosamine 1-phosphate
Reference
PMID:2793832
  Authors
Wyk P, Reeves P
  Title
Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase.
  Journal
J Bacteriol 171:5687-93 (1989)
DOI:10.1128/JB.171.10.5687-5693.1989
Reference
PMID:8071227
  Authors
Thorson JS, Lo SF, Ploux O, He X, Liu HW
  Title
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.
  Journal
J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994
Reference
PMID:8444803
  Authors
Kessler AC, Haase A, Reeves PR
  Title
Molecular analysis of the 3,6-dideoxyhexose pathway genes of Yersinia pseudotuberculosis serogroup IIA.
  Journal
J Bacteriol 175:1412-22 (1993)
DOI:10.1128/JB.175.5.1412-1422.1993
Reference
PMID:9811644
  Authors
Danese PN, Oliver GR, Barr K, Bowman GD, Rick PD, Silhavy TJ
  Title
Accumulation of the enterobacterial common antigen lipid II biosynthetic intermediate stimulates degP transcription in Escherichia coli.
  Journal
J Bacteriol 180:5875-84 (1998)
DOI:10.1128/JB.180.22.5875-5884.1998
Reference
  Authors
Skurnik M, Peippo A, Ervela E
  Title
Characterization of the O-antigen gene clusters of Yersinia pseudotuberculosis and the cryptic O-antigen gene cluster of Yersinia pestis shows that the plague bacillus is most closely related to and has evolved from Y. pseudotuberculosis serotype O:1b.
  Journal
Mol Microbiol 37:316-30 (2000)
DOI:10.1046/j.1365-2958.2000.01993.x
Reference
  Authors
Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV
  Title
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
  Journal
Nature 406:959-64 (2000)
DOI:10.1038/35023079
Reference
  Authors
Ringenberg M, Lichtensteiger C, Vimr E
  Title
Redirection of sialic acid metabolism in genetically engineered Escherichia coli.
  Journal
Glycobiology 11:533-9 (2001)
DOI:10.1093/glycob/11.7.533
Reference
  Authors
McCoy AJ, Sandlin RC, Maurelli AT
  Title
In vitro and in vivo functional activity of Chlamydia MurA, a UDP-N-acetylglucosamine enolpyruvyl transferase involved in peptidoglycan synthesis and fosfomycin resistance.
  Journal
J Bacteriol 185:1218-28 (2003)
DOI:10.1128/JB.185.4.1218-1228.2003
Reference
  Authors
JACOBSON B, DAVIDSON EA
  Title
Biosynthesis of uronic acids by skin enzymes. I. Uridine diphosphate-D-glucuronic acid-5-epimerase.
  Journal
J Biol Chem 237:638-42 (1962)
Reference
  Authors
Seifert GJ
  Title
Nucleotide sugar interconversions and cell wall biosynthesis: how to bring the inside to the outside.
  Journal
Curr Opin Plant Biol 7:277-84 (2004)
DOI:10.1016/j.pbi.2004.03.004
Reference
  Authors
Uehara T, Park JT
  Title
The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling.
  Journal
J Bacteriol 186:7273-9 (2004)
DOI:10.1128/JB.186.21.7273-7279.2004
Reference
  Authors
Breazeale SD, Ribeiro AA, McClerren AL, Raetz CR.
  Title
A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose.
  Journal
J Biol Chem 280:14154-67 (2005)
DOI:10.1074/jbc.M414265200
Reference
  Authors
Williams GJ, Breazeale SD, Raetz CR, Naismith JH.
  Title
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis.
  Journal
J Biol Chem 280:23000-8 (2005)
DOI:10.1074/jbc.M501534200
Reference
  Authors
Maliekal P, Vertommen D, Delpierre G, Van Schaftingen E
  Title
Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase.
  Journal
Glycobiology 16:165-72 (2006)
DOI:10.1093/glycob/cwj050
Reference
  Authors
Campbell CT, Yarema KJ
  Title
Large-scale approaches for glycobiology.
  Journal
Genome Biol 6:236 (2005)
DOI:10.1186/gb-2005-6-11-236
Reference
  Authors
Uehara T, Suefuji K, Jaeger T, Mayer C, Park JT
  Title
MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall.
  Journal
J Bacteriol 188:1660-2 (2006)
DOI:10.1128/JB.188.4.1660-1662.2006
Reference
  Authors
Lanot A, Hodge D, Jackson RG, George GL, Elias L, Lim EK, Vaistij FE, Bowles DJ
  Title
The glucosyltransferase UGT72E2 is responsible for monolignol 4-O-glucoside production in Arabidopsis thaliana.
  Journal
Plant J 48:286-95 (2006)
DOI:10.1111/j.1365-313X.2006.02872.x
Reference
  Authors
Muller R, Morant M, Jarmer H, Nilsson L, Nielsen TH
  Title
Genome-wide analysis of the Arabidopsis leaf transcriptome reveals interaction of phosphate and sugar metabolism.
  Journal
Plant Physiol 143:156-71 (2007)
DOI:10.1104/pp.106.090167
Reference
  Authors
Oka T, Nemoto T, Jigami Y
  Title
Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion.
  Journal
J Biol Chem 282:5389-403 (2007)
DOI:10.1074/jbc.M610196200
Reference
  Authors
Greenberg DE, Porcella SF, Zelazny AM, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Barbian KD, Babar A, Dorward DW, Holland SM.
  Title
Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis.
  Journal
J Bacteriol 189:8727-36 (2007)
DOI:10.1128/JB.00793-07
Reference
  Authors
Kotake T, Hojo S, Tajima N, Matsuoka K, Koyama T, Tsumuraya Y
  Title
A bifunctional enzyme with L-fucokinase and GDP-L-fucose pyrophosphorylase activities salvages free L-fucose in Arabidopsis.
  Journal
J Biol Chem 283:8125-35 (2008)
DOI:10.1074/jbc.M710078200
Reference
  Authors
Vorholter FJ, Schneiker S, Goesmann A, Krause L, Bekel T, Kaiser O, Linke B, Patschkowski T, Ruckert C, Schmid J, Sidhu VK, Sieber V, Tauch A, Watt SA, Weisshaar B, Becker A, Niehaus K, Puhler A.
  Title
The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis.
  Journal
J Biotechnol 134:33-45 (2008)
DOI:10.1016/j.jbiotec.2007.12.013
Reference
  Authors
Albermann C, Piepersberg W
  Title
Expression and identification of the RfbE protein from Vibrio cholerae O1 and its use for the enzymatic synthesis of GDP-D-perosamine.
  Journal
Glycobiology 11:655-61 (2001)
DOI:10.1093/glycob/11.8.655
Related
pathway
bxh00010  Glycolysis / Gluconeogenesis
bxh00040  Pentose and glucuronate interconversions
bxh00051  Fructose and mannose metabolism
bxh00052  Galactose metabolism
bxh00053  Ascorbate and aldarate metabolism
bxh00500  Starch and sucrose metabolism
bxh00521  Streptomycin biosynthesis
bxh00523  Polyketide sugar unit biosynthesis
bxh00525  Acarbose and validamycin biosynthesis
bxh00541  Biosynthesis of various nucleotide sugars
bxh00550  Peptidoglycan biosynthesis
KO pathway
ko00520   

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