KEGG   PATHWAY: cjei00010
Entry
cjei00010                   Pathway                                
Name
Glycolysis / Gluconeogenesis - Campylobacter jejuni subsp. jejuni 00-2425
Description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
Class
Metabolism; Carbohydrate metabolism
Pathway map
cjei00010  Glycolysis / Gluconeogenesis
cjei00010

Module
cjei_M00002  Glycolysis, core module involving three-carbon compounds [PATH:cjei00010]
cjei_M00003  Gluconeogenesis, oxaloacetate => fructose-6P [PATH:cjei00010]
cjei_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:cjei00010]
Other DBs
GO: 0006096 0006094
Organism
Campylobacter jejuni subsp. jejuni 00-2425 [GN:cjei]
Gene
N135_01622  glucose-6-phosphate isomerase [KO:K01810] [EC:5.3.1.9]
N135_00883  fructose 1,6-bisphosphatase [KO:K03841] [EC:3.1.3.11]
N135_00648  fructose-bisphosphate aldolase [KO:K01624] [EC:4.1.2.13]
N135_01490  triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
N135_01492  glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
N135_01491  pgk; phosphoglycerate kinase [KO:K00927] [EC:2.7.2.3]
N135_00482  phosphoglyceromutase [KO:K15633] [EC:5.4.2.12]
N135_01761  eno; enolase [KO:K01689] [EC:4.2.1.11]
N135_00436  pyruvate kinase [KO:K00873] [EC:2.7.1.40]
N135_01566  pyruvate-flavodoxin oxidoreductase [KO:K03737] [EC:1.2.7.1 1.2.7.-]
N135_00585  2-oxoglutarate ferredoxin oxidoreductase subunit alpha [KO:K00174] [EC:1.2.7.3 1.2.7.11]
N135_00586  2-oxoglutarate ferredoxin oxidoreductase subunit beta [KO:K00175] [EC:1.2.7.3 1.2.7.11]
N135_01201  lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
N135_01635  alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
N135_01624  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
N135_01496  phospho-sugar mutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
N135_00969  phosphoenolpyruvate carboxykinase [KO:K01610] [EC:4.1.1.49]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00031  D-Glucose
C00033  Acetate
C00036  Oxaloacetate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00084  Acetaldehyde
C00085  D-Fructose 6-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00186  (S)-Lactate
C00197  3-Phospho-D-glycerate
C00221  beta-D-Glucose
C00236  3-Phospho-D-glyceroyl phosphate
C00267  alpha-D-Glucose
C00354  D-Fructose 1,6-bisphosphate
C00469  Ethanol
C00631  2-Phospho-D-glycerate
C00668  alpha-D-Glucose 6-phosphate
C01159  2,3-Bisphospho-D-glycerate
C01172  beta-D-Glucose 6-phosphate
C01451  Salicin
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C06186  Arbutin
C06187  Arbutin 6-phosphate
C06188  Salicin 6-phosphate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y (ed).
  Title
[Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1980)
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Michal G.
  Title
Biochemical Pathways
  Journal
Wiley (1999)
Related
pathway
cjei00020  Citrate cycle (TCA cycle)
cjei00030  Pentose phosphate pathway
cjei00500  Starch and sucrose metabolism
cjei00620  Pyruvate metabolism
cjei00640  Propanoate metabolism
cjei00710  Carbon fixation by Calvin cycle
KO pathway
ko00010   
LinkDB

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