KEGG   PATHWAY: cmk00190
Entry
cmk00190                    Pathway                                
Name
Oxidative phosphorylation - Callorhinchus milii (elephant shark)
Class
Metabolism; Energy metabolism
Pathway map
cmk00190  Oxidative phosphorylation
cmk00190

Module
cmk_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:cmk00190]
cmk_M00151  Cytochrome bc1 complex respiratory unit [PATH:cmk00190]
Organism
Callorhinchus milii (elephant shark) [GN:cmk]
Gene
9385357  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
9385345  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
9385351  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
9385353  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
9385352  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
9385354  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
9385355  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
103182876  ndufs1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial [KO:K03934] [EC:7.1.1.2]
103175779  NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935] [EC:7.1.1.2]
121850168  NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial-like [KO:K03935] [EC:7.1.1.2]
121850203  NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial-like [KO:K03935] [EC:7.1.1.2]
103174958  ndufs3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1 [KO:K03936] [EC:7.1.1.2]
103177881  ndufs4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937]
103188701  ndufs5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
103184803  ndufs6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
103181937  ndufs7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial [KO:K03940] [EC:7.1.1.2]
103172416  NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941] [EC:7.1.1.2]
103181050  ndufv2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
103178436  ndufa1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
103184104  ndufa2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
103183824  ndufa4a; cytochrome c oxidase subunit NDUFA4L [KO:K03948]
103185995  cytochrome c oxidase subunit NDUFA4 isoform X1 [KO:K03948]
103181840  ndufa5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
103173699  ndufa6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
103190432  ndufa7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
103184670  ndufa8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
103185570  ndufa9a; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
103189997  ndufa10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
103186621  ndufab1b; acyl carrier protein, mitochondrial [KO:K03955]
103188857  ndufa12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
103181998  ndufa13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
103185390  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
103186216  ndufb2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958]
103188651  ndufb4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
103175888  ndufb5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
103187213  ndufb6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
103187588  ndufb7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
103182445  ndufb8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
103185083  ndufb9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
103186846  ndufb10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
103181302  ndufc1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
103177141  ndufc2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
103181549  sdha; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [KO:K00234] [EC:1.3.5.1]
103187447  sdhb; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
103191157  sdhdb; succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial [KO:K00237]
103176055  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
9385356  CYTB; cytochrome b [KO:K00412]
103189055  cytochrome c1, heme protein, mitochondrial [KO:K00413]
103178744  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
103182727  cytochrome b-c1 complex subunit 6, mitochondrial [KO:K00416]
103175126  cytochrome b-c1 complex subunit 7 [KO:K00417]
103177334  cytochrome b-c1 complex subunit 8 [KO:K00418]
103184356  cytochrome b-c1 complex subunit 9 [KO:K00419]
103189693  cytochrome b-c1 complex subunit 10 [KO:K00420]
103175416  protoheme IX farnesyltransferase, mitochondrial isoform X2 [KO:K02257] [EC:2.5.1.141]
9385350  COX3; cytochrome c oxidase subunit III [KO:K02262]
9385346  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
9385347  COX2; cytochrome c oxidase subunit II [KO:K02261]
103175926  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
103188980  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
103181102  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
103188994  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
103174840  cytochrome c oxidase subunit 6A, mitochondrial [KO:K02266]
103182196  cytochrome c oxidase subunit 6A, mitochondrial [KO:K02266]
103175179  cytochrome c oxidase subunit 6C [KO:K02268]
103177996  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
103189501  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
103178978  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
103182668  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
103171903  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
103177071  cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
103186568  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
103180162  cytochrome c oxidase copper chaperone [KO:K02260]
103176492  cytochrome c iso-1/iso-2-like [KO:K08738]
103183182  cytochrome c [KO:K08738]
121852224  cytochrome c, somatic [KO:K08738]
103188803  atp5fa1; ATP synthase subunit alpha, mitochondrial [KO:K02132]
103176391  atp5f1b; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
103187927  atp5f1c; ATP synthase subunit gamma, mitochondrial [KO:K02136]
103182080  atp5f1d; ATP synthase subunit delta, mitochondrial [KO:K02134]
103191538  atp5f1e; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
103186749  atp5po; ATP synthase subunit O, mitochondrial [KO:K02137]
9385349  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
103182497  atp5pb; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127]
103185711  atp5mc1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
103189300  atp5mc3a; ATP synthase membrane subunit c locus 3a isoform X1 [KO:K02128]
103175636  atp5pd; ATP synthase subunit d, mitochondrial [KO:K02138]
103186860  atp5mf; ATP synthase subunit f, mitochondrial [KO:K02130]
103173013  ATP synthase subunit f, mitochondrial [KO:K02130]
103180333  atp5l; ATP synthase subunit g, mitochondrial [KO:K02140]
103188602  atp5pf; ATP synthase-coupling factor 6, mitochondrial [KO:K02131]
9385348  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
103177564  atp6v1ab; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:7.1.2.2]
103185238  atp6v1ba; V-type proton ATPase subunit B, kidney isoform [KO:K02147]
103187781  V-type proton ATPase subunit B, brain isoform isoform X1 [KO:K02147]
103175146  atp6v1c1a; V-type proton ATPase subunit C 1-A [KO:K02148]
103180947  atp6v1c2; V-type proton ATPase subunit C 2 [KO:K02148]
103175214  atp6v1d; V-type proton ATPase subunit D [KO:K02149]
103186128  atp6v1e1b; V-type proton ATPase subunit E 1 [KO:K02150]
103190016  atp6v1f; V-type proton ATPase subunit F [KO:K02151]
103174772  V-type proton ATPase subunit G 3 [KO:K02152]
103189285  atp6v1g1; V-type proton ATPase subunit G 1 [KO:K02152]
103186718  atp6v1h; V-type proton ATPase subunit H [KO:K02144]
103189172  V-type proton ATPase 116 kDa subunit a1 isoform X1 [KO:K02154]
103187833  V-type proton ATPase 116 kDa subunit a2 isoform X1 [KO:K02154]
103188002  V-type proton ATPase 116 kDa subunit a2 [KO:K02154]
103189838  V-type proton ATPase 116 kDa subunit a [KO:K02154]
103181272  V-type proton ATPase 116 kDa subunit a1-like [KO:K02154]
103178723  atp6v0cb; V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
103182792  V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
121849174  V-type proton ATPase 21 kDa proteolipid subunit-like [KO:K03661]
103190837  atp6v0d1; V-type proton ATPase subunit d 1 [KO:K02146]
103187234  atp6v0e1; V-type proton ATPase subunit e 1 [KO:K02153]
103190289  atpv0e2; ATPase H+ transporting V0 subunit e2 [KO:K02153]
103177661  inorganic pyrophosphatase isoform X1 [KO:K01507] [EC:3.6.1.1]
103182217  inorganic pyrophosphatase-like [KO:K01507] [EC:3.6.1.1]
103185447  lhpp; phospholysine phosphohistidine inorganic pyrophosphate phosphatase [KO:K11725] [EC:3.6.1.1 3.1.3.-]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00080  H+
C00122  Fumarate
C00536  Triphosphate
Reference
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   
LinkDB

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