KEGG   PATHWAY: cnc02020
Entry
cnc02020                    Pathway                                
Name
Two-component system - Cupriavidus necator N-1
Description
Two-component signal transduction systems enable bacteria to sense, respond, and adapt to changes in their environment or in their intracellular state. Each two-component system consists of a sensor protein-histidine kinase (HK) and a response regulator (RR). In the prototypical two-component pathway, the sensor HK phosphorylates its own conserved His residue in response to a signal(s) in the environment. Subsequently, the phosphoryl group of HK is transferred onto a specific Asp residue on the RR. The activated RR can then effect changes in cellular physiology, often by regulating gene expression. Two-component pathways thus often enable cells to sense and respond to stimuli by inducing changes in transcription.
Class
Environmental Information Processing; Signal transduction
Pathway map
cnc02020  Two-component system
cnc02020

Other DBs
GO: 0000160
Organism
Cupriavidus necator N-1 [GN:cnc]
Gene
CNE_1c00010  dnaA; chromosomal replication initiator protein DnaA [KO:K02313]
CNE_1c01610  thlA; acetyl-CoA acetyltransferase ThlA [KO:K00626] [EC:2.3.1.9]
CNE_1c01920  [KO:K15012]
CNE_1c01930  [KO:K15011] [EC:2.7.13.3]
CNE_1c02950  crp; transcriptional regulator CRP family [KO:K10914]
CNE_1c03060  creC; sensor protein CreC [KO:K07641] [EC:2.7.13.3]
CNE_1c03070  creB; transcriptional regulatory protein CreB [KO:K07663]
CNE_1c03090  dctD; C4-dicarboxylatetransporttranscriptional regulatory protein DctD [KO:K10126]
CNE_1c03100  dctB; C4-dicarboxylate transport sensor protein DctB [KO:K10125] [EC:2.7.13.3]
CNE_1c03110  dctA1; C4-dicarboxylate transport protein DctA [KO:K11103]
CNE_1c03680  ctaA; hemeA synthase CtaA [KO:K02259] [EC:1.17.99.9]
CNE_1c04030  rpoN; RNA polymerase sigma-54 factor RpoN [KO:K03092]
CNE_1c04320  gltI1; glutamate/aspartate ABC transport system permease protein GltI [KO:K10001]
CNE_1c04940  gltI2; glutamate/aspartate ABC transport system permease protein GltI [KO:K10001]
CNE_1c04950  gltJ; glutamate/aspartate ABC transport system permease protein GltJ [KO:K10003]
CNE_1c04960  gltK; glutamate/aspartate ABC transport system permease protein GltK [KO:K10002]
CNE_1c04970  gltL; glutamate/aspartate ABC transport system ATP-binding protein GltL [KO:K10004] [EC:7.4.2.1]
CNE_1c05580  [KO:K07688]
CNE_1c05720  pilA; type IV pilus structural subunit PilA [KO:K02650]
CNE_1c06090  acrB1; cation/multidrug efflux pump [KO:K07789]
CNE_1c06100  acrB2; cation/multidrug efflux pump [KO:K07788]
CNE_1c06110  acrA1; cation/multidrug efflux system, mebrane-fusion component AcrA [KO:K07799]
CNE_1c06120  ompR1; transcriptional regulatory protein OmpR [KO:K07659]
CNE_1c06130  envZ1; osmolarity sensor protein EnvZ [KO:K07638] [EC:2.7.13.3]
CNE_1c06840  gltR; response regulator of C4-dicarboxylatetransportsystem [KO:K17061]
CNE_1c06850  gltS; signaltransduction histidine kinase regulating C4-dicarboxylatetransport system [KO:K17060] [EC:2.7.13.3]
CNE_1c07090  tadC; Flp pilus assembly protein TadC [KO:K12511]
CNE_1c07100  tadB; Flp pilus assembly protein TadB [KO:K12510]
CNE_1c07110  cpaF; Flp pilus assembly ATPase CpaF [KO:K02283] [EC:7.4.2.8]
CNE_1c07120  cpaE; Flp pilus assembly ATPase CpaE [KO:K02282]
CNE_1c07170  cpaC; Flp pilus assembly protein secretin CpaC [KO:K02280]
CNE_1c07180  cpaB; Flp pilus assembly protein CpaB [KO:K02279]
CNE_1c07210  flp1; Flp pilus assembly protein pilin Flp [KO:K02651]
CNE_1c07220  flp2; Flp pilus assembly protein pilin Flp [KO:K02651]
CNE_1c07420  pilG; type IV pilus response regulator PilG [KO:K02657]
CNE_1c07430  pilH; type IV pilus response regulator PilH [KO:K02658]
CNE_1c07440  pilI; type IV pilus signal transduction protein PilI [KO:K02659]
CNE_1c07450  pilJ; type IV pilus transmembrane protein PilJ [KO:K02660]
CNE_1c07460  pilL; type IV pilus protein histidine kinase/response regulator hybrid PilL [KO:K06596]
CNE_1c07600  glnB; nitrogen regulatory protein GlnB [KO:K04751]
CNE_1c07810  gltI3; glutamate/aspartate ABC transport system permease protein GltI [KO:K10001]
CNE_1c07920  degS; sensor protein DegS [KO:K07675] [EC:2.7.13.3]
CNE_1c09550  [KO:K10255] [EC:1.14.19.23 1.14.19.45]
CNE_1c10980  epsP; low molecular weight protein-tyrosine-phosphatase EpsP [KO:K25307]
CNE_1c12900  [KO:K00626] [EC:2.3.1.9]
CNE_1c13160  [KO:K11689]
CNE_1c13170  [KO:K11690]
CNE_1c13180  [KO:K11688]
CNE_1c14550  [KO:K07666]
CNE_1c14560  qseC2; sensor protein QseC [KO:K07645] [EC:2.7.13.3]
CNE_1c14660  phaA1; acetyl-CoA acetyltransferase PhaA [KO:K00626] [EC:2.3.1.9]
CNE_1c14710  bktB; acetyl-CoA acetyltransferase BktB [KO:K00626] [EC:2.3.1.9]
CNE_1c14890  envZ2; osmolarity sensor protein EnvZ [KO:K07638] [EC:2.7.13.3]
CNE_1c14900  ompR2; transcriptional regulatory protein OmpR [KO:K07659]
CNE_1c15340  [KO:K11690]
CNE_1c15350  [KO:K11689]
CNE_1c15360  [KO:K11688]
CNE_1c15600  fadA2; 3-ketoacyl-CoA thiolase FadA [KO:K00626] [EC:2.3.1.9]
CNE_1c16630  [KO:K07795]
CNE_1c17240  [KO:K07687]
CNE_1c18890  ansB2; glutaminase-asparaginase AnsB [KO:K05597] [EC:3.5.1.38]
CNE_1c19180  yiaO; 2,3-diketo-L-gulonate-binding periplasmic protein YiaO [KO:K11688]
CNE_1c19950  glnD; [protein-PII] uridylyltransferase GlnD [KO:K00990] [EC:2.7.7.59]
CNE_1c20660  dctA2; C4-dicarboxylate transport protein DctA [KO:K11103]
CNE_1c20800  [KO:K12340]
CNE_1c20990  phoA1; alkaline phosphatase PhoA [KO:K01077] [EC:3.1.3.1]
CNE_1c21000  phoA2; alkaline phosphatase PhoA [KO:K01077] [EC:3.1.3.1]
CNE_1c21020  czcC; cobalt-zinc-cadmium resistance outer membrane porin CzcC [KO:K07796]
CNE_1c21030  czcA; cobalt-zinc-cadmium resistance membrane-fusion protein CzcA [KO:K07798]
CNE_1c21040  czcB; cobalt-zinc-cadmium resistance efflux pump CzcB [KO:K07787]
CNE_1c21050  [KO:K07810]
CNE_1c21980  tsr; methyl-accepting chemotaxis protein I [KO:K05874]
CNE_1c22260  ccoP; Cbb3-type cytochrome oxidase, diheme subunit IV [KO:K00406]
CNE_1c22270  ccoQ; Cbb3-type cytochrome oxidase, subunit III [KO:K00407]
CNE_1c22280  ccoO; Cbb3-type cytochrome oxidase, monoheme subunit II [KO:K00405]
CNE_1c22290  ccoN; cbb3-type cytochrome C oxidase subunit I [KO:K00404] [EC:7.1.1.9]
CNE_1c22420  ntrC; response regulator nitrogen regulation protein NtrC [KO:K07712]
CNE_1c22430  ntrB; nitrogen regulation protein NtrB [KO:K07708] [EC:2.7.13.3]
CNE_1c22890  tctD2; transcriptional regulatory protein TctD [KO:K07774]
CNE_1c22900  qseC3; sensor protein QseC [KO:K07649] [EC:2.7.13.3]
CNE_1c23470  phoR; phosphate regulon sensor protein PhoR [KO:K07636] [EC:2.7.13.3]
CNE_1c23480  phoB; phosphate regulontranscriptional regulatory protein PhoB [KO:K07657]
CNE_1c23530  pstS; phosphate-binding protein PstS [KO:K02040]
CNE_1c24440  degP1; serine protease do-like protein [KO:K04771] [EC:3.4.21.107]
CNE_1c24820  kdpE; KDP operontranscriptional regulatory protein KdpE [KO:K07667]
CNE_1c24830  kdpD; osmosensitive K+ channel histidine kinase KdpD [KO:K07646] [EC:2.7.13.3]
CNE_1c25180  citE; citrate lyase beta subunit [KO:K01644] [EC:4.1.3.34]
CNE_1c26650  [KO:K07793]
CNE_1c28170  acrC2; cation/multidrug efflux system outer membrane porin [KO:K12340]
CNE_1c28500  wecB1; UDP-N-acetylglucosamine 2-epimerase WecB [KO:K01791] [EC:5.1.3.14]
CNE_1c28760  [KO:K11689]
CNE_1c28770  [KO:K11690]
CNE_1c29640  wecB2; UDP-N-acetylglucosamine 2-epimerase WecB [KO:K01791] [EC:5.1.3.14]
CNE_1c30750  phcR; signal transduction histidine kinase PhcR [KO:K19622]
CNE_1c30760  fixL; sensor protein FixL [KO:K19621] [EC:2.7.13.3]
CNE_1c30770  phcB6; S-adenosyl-L-methionine (SAM)-dependent methyltransferase PhcB [KO:K19620]
CNE_1c31000  phcA; transcriptional regulator LysR family [KO:K19624]
CNE_1c31470  [KO:K03406]
CNE_1c31700  pilR; type 4 fimbriae expression regulatory protein PilR [KO:K02667]
CNE_1c31710  pilS; sensor protein PilS [KO:K02668] [EC:2.7.13.3]
CNE_1c33360  qcrC; ubiquinol-cytochrome c reductase, cytochrome c1 [KO:K00413]
CNE_1c33370  qcrB; ubiquinol-cytochrome-c reductase, cytochrome b [KO:K00412]
CNE_1c33380  petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [KO:K00411] [EC:7.1.1.8]
CNE_1c35200  [KO:K08738]
CNE_1c35390  dctA3; C4-dicarboxylate transport protein DctA [KO:K11103]
CNE_1c35530  acrD; aminoglycoside efflux pump [KO:K18095]
CNE_1c36390  [KO:K11688]
CNE_1c36450  ntrX; response regulator NtrX [KO:K13599]
CNE_1c36460  ntrY; nitrogen regulation protein NtrY [KO:K13598] [EC:2.7.13.3]
CNE_1c36680  acrA5; cation/multidrug efflux system, mebrane-fusion component AcrA [KO:K07799]
CNE_1c36690  [KO:K07788]
CNE_1c36710  tctC; periplasmic tricarboxylate binding receptor TctC [KO:K07795]
CNE_1c36720  tctB; component of transporter, tripartite tricarboxylate transport (TTT) family [KO:K07794]
CNE_1c36730  tctA; tricarboxylate transport protein TctA [KO:K07793]
CNE_1c36780  rssA; swarming motility regulation sensor protein RssA [KO:K07649] [EC:2.7.13.3]
CNE_1c36790  tctD3; transcriptional regulatory protein TctD [KO:K07774]
CNE_2c00110  epsB1; tyrosine-protein kinase EpsB [KO:K16692] [EC:2.7.10.3]
CNE_2c00130  epsB2; tyrosine-protein kinase EpsB [KO:K16692] [EC:2.7.10.3]
CNE_2c00140  epsP1; low molecular weight protein-tyrosine-phosphatase EpsP [KO:K25307]
CNE_2c00150  epsA1; polysaccharide export outer membrane protein EpsA [KO:K01991]
CNE_2c01090  [KO:K07690]
CNE_2c01440  degP1; serine protease do-like protein [KO:K04771] [EC:3.4.21.107]
CNE_2c01660  [KO:K02651]
CNE_2c01690  cpaB; Flp pilus assembly protein CpaB [KO:K02279]
CNE_2c01700  cpaC; Flp pilus assembly protein secretin CpaC [KO:K02280]
CNE_2c01710  cpaE; Flp pilus assembly ATPase CpaE [KO:K02282]
CNE_2c01720  cpaF; Flp pilus assembly ATPase CpaF [KO:K02283] [EC:7.4.2.8]
CNE_2c01730  tadB; Flp pilus assembly protein TadB [KO:K12510]
CNE_2c01740  tadC; Flp pilus assembly protein TadC [KO:K12511]
CNE_2c01750  tadD; Flp pilus assembly protein TadD [KO:K27079]
CNE_2c01770  [KO:K27080]
CNE_2c02180  [KO:K05874]
CNE_2c02200  cheY1; chemotaxis response regulator [KO:K03413]
CNE_2c02210  cheW1; chemotaxis protein CheW [KO:K03408]
CNE_2c02220  [KO:K03776]
CNE_2c02230  [KO:K03406]
CNE_2c02250  flhD; transcriptional activator FlhD [KO:K02403]
CNE_2c02260  flhC1; flagellar transcriptional activator FlhC [KO:K02402]
CNE_2c02270  motA; flagellar motor component MotA [KO:K02556]
CNE_2c02290  cheA1; chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
CNE_2c02300  cheW2; chemotaxis protein CheW [KO:K03408]
CNE_2c02310  cheR1; chemotaxis protein methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
CNE_2c02330  cheB1; chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
CNE_2c02340  cheY2; chemotaxis response regulator [KO:K03413]
CNE_2c02430  fliA; DNA-directed RNA polymerase flagellum specific sigma subunit [KO:K02405]
CNE_2c02460  flgM; negative regulator of flagellin synthesis [KO:K02398]
CNE_2c02940  [KO:K07687]
CNE_2c02950  rcsC1; sensor protein RcsC [KO:K07677] [EC:2.7.13.3]
CNE_2c04350  cqsS1; CAI-1 autoinducer sensor kinase/phosphatase CqsS [KO:K10916] [EC:2.7.13.3 3.1.3.-]
CNE_2c05010  tse; methyl-accepting chemotaxis serine transducer Tse [KO:K03406]
CNE_2c05650  glnA; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
CNE_2c06150  fadA1; 3-ketoacyl-CoA thiolase FadA [KO:K00626] [EC:2.3.1.9]
CNE_2c06320  [KO:K01644] [EC:4.1.3.34]
CNE_2c08020  [KO:K10914]
CNE_2c08050  phoD; alkaline phosphatase PhoD [KO:K01113] [EC:3.1.3.1]
CNE_2c08490  [KO:K07667]
CNE_2c08500  kdpD; osmosensitive K+ channel histidine kinase KdpD [KO:K07646] [EC:2.7.13.3]
CNE_2c08510  kdpC; potassium-transporting ATPase C chain [KO:K01548]
CNE_2c08520  kdpB; potassium-transporting ATPase B chain [KO:K01547] [EC:7.2.2.6]
CNE_2c08530  kdpA; potassium-transporting ATPase A chain [KO:K01546]
CNE_2c08840  flhC2; flagellar transcriptional activator FlhC [KO:K02402]
CNE_2c10090  [KO:K08738]
CNE_2c11060  [KO:K10914]
CNE_2c11370  appB; cytochrome bd-II oxidase subunit 2 [KO:K00426] [EC:7.1.1.7]
CNE_2c11380  appC; cytochrome bd-II oxidase subunit 1 [KO:K00425] [EC:7.1.1.7]
CNE_2c11530  [KO:K10914]
CNE_2c12090  phoC; major phosphate-irrepressible acid phosphatase PhoC [KO:K09474] [EC:3.1.3.2]
CNE_2c12130  [KO:K10914]
CNE_2c12230  mcpA; chemoreceptor McpA [KO:K03406]
CNE_2c12720  ampC1; beta-lactamase AmpC [KO:K01467] [EC:3.5.2.6]
CNE_2c13280  phaA; acetyl-CoA acetyltransferase PhaA [KO:K00626] [EC:2.3.1.9]
CNE_2c13560  dctA; C4-dicarboxylate transport protein DctA [KO:K11103]
CNE_2c13930  [KO:K19667]
CNE_2c14070  epsB3; tyrosine-protein kinase EpsB [KO:K16692] [EC:2.7.10.3]
CNE_2c14080  epsP2; low molecular weight protein-tyrosine-phosphatase EpsP [KO:K25307]
CNE_2c14090  epsA2; polysaccharide export outer membrane protein EpsA [KO:K01991]
CNE_2c14340  fdoG; formate dehydrogenase alpha subunit [KO:K08348] [EC:1.17.5.3]
CNE_2c14530  cydA; cytochrome d ubiquinol oxidase subunit 1 [KO:K00425] [EC:7.1.1.7]
CNE_2c14540  cydB; Bd-type quinol oxidase subunit I [KO:K00426] [EC:7.1.1.7]
CNE_2c14780  oxlT1; oxalate:formate antiporter OxlT [KO:K08177]
CNE_2c15870  atoE1; short-chain fatty acids transporter AtoE [KO:K02106]
CNE_2c16390  [KO:K07644] [EC:2.7.13.3]
CNE_2c16400  [KO:K07665]
CNE_2c16780  oxlT2; oxalate / formate antiporter MFS-type OFA family [KO:K08177]
CNE_2c16880  oxlT3; oxalate:formate antiporter OxlT [KO:K08177]
CNE_2c17560  [KO:K07795]
CNE_2c17630  [KO:K07795]
CNE_2c18940  tsr1; methyl-accepting chemotaxis protein I [KO:K03406]
CNE_2c19370  rcsB; capsular synthesis regulator component B [KO:K07687]
CNE_2c19950  mcp; methyl-accepting chemotaxis transducer [KO:K13487]
CNE_2c19960  cheW2; chemotaxis signal transduction protein CheW [KO:K13488]
CNE_2c19970  cheR2; methylase of chemotaxis methyl-accepting proteins CheR [KO:K13486]
CNE_2c19980  [KO:K13489]
CNE_2c19990  cheA2; chemotaxis protein CheA [KO:K13490]
CNE_2c20000  cheB2; chemotaxis response regulator protein-glutamate methylesterase [KO:K13491] [EC:3.1.1.61]
CNE_2c20010  [KO:K11444] [EC:2.7.7.65]
CNE_2c20040  [KO:K07793]
CNE_2c20050  [KO:K07794]
CNE_2c20350  [KO:K07687]
CNE_2c20660  citE; citrate lyase beta subunit [KO:K01644] [EC:4.1.3.34]
CNE_2c20880  tar; methyl-accepting chemotaxis protein Tar [KO:K03406]
CNE_2c21430  [KO:K11688]
CNE_2c21450  [KO:K11689]
CNE_2c21460  dctM; tripartite ATP-independent periplasmic (TRAP-type) dicarboxylate transporter, DctM subunit [KO:K11690]
CNE_2c21710  copR; response regulator of copper response OmpR family [KO:K07665]
CNE_2c21720  cusS; sensor kinase CusS [KO:K07644] [EC:2.7.13.3]
CNE_2c22180  cheV; chemotaxis specific response regulator containing a CheW-domain [KO:K03415]
CNE_2c22330  narG; respiratory nitrate reductase 1 alpha subunit [KO:K00370] [EC:1.7.5.1 1.7.99.-]
CNE_2c22340  narH; respiratory nitrate reductase 1 beta subunit [KO:K00371] [EC:1.7.5.1 1.7.99.-]
CNE_2c22350  narJ; respiratory nitrate reductase subunit [KO:K00373]
CNE_2c22360  narI; respiratory nitrate reductase 1 gamma subunit [KO:K00374] [EC:1.7.5.1 1.7.99.-]
CNE_2c22650  tsr2; methyl-accepting chemotaxis protein I [KO:K03406]
CNE_2c22800  [KO:K08738]
CNE_2c22840  atoE3; short-chain fatty acids transporter AtoE [KO:K02106]
CNE_2c22980  narX; signal transduction histidine kinase nitrate/nitrite-specific [KO:K07673] [EC:2.7.13.3]
CNE_2c22990  [KO:K07684]
CNE_2c23140  [KO:K07713]
CNE_2c23150  [KO:K07713]
CNE_2c23260  fliC; flagellin FliC [KO:K02406]
CNE_2c24040  tsr3; methyl-accepting chemotaxis protein I [KO:K03406]
CNE_BB1p00450  frdB; fumarate reductase iron-sulfur subunit [KO:K00245] [EC:1.3.5.1]
CNE_BB1p00460  [KO:K00246]
CNE_BB1p00470  [KO:K00247]
CNE_BB1p00480  [KO:K00244] [EC:1.3.5.1]
CNE_BB1p00540  [KO:K07795]
CNE_BB1p01450  citE; citrate lyase beta subunit [KO:K01644] [EC:4.1.3.34]
CNE_BB1p01460  [KO:K11690]
CNE_BB1p01470  [KO:K11689]
CNE_BB1p01480  dctP; tripartite ATP-independent periplasmic (TRAP-type) dicarboxylate transporter, DctP subunit [KO:K11688]
CNE_BB1p02570  thlA; acetyl-CoA acetyltransferase ThlA [KO:K00626] [EC:2.3.1.9]
CNE_BB1p02580  [KO:K10914]
CNE_BB1p03780  [KO:K00626] [EC:2.3.1.9]
CNE_BB1p04450  [KO:K07658]
CNE_BB1p04700  [KO:K00626] [EC:2.3.1.9]
CNE_BB1p05180  [KO:K00626] [EC:2.3.1.9]
CNE_BB1p05190  [KO:K00626] [EC:2.3.1.9]
CNE_BB1p05870  [KO:K00626] [EC:2.3.1.9]
CNE_BB1p08600  fadA2; 3-ketoacyl-CoA thiolase FadA [KO:K00626] [EC:2.3.1.9]
CNE_BB1p08760  flhD; transcriptional activator FlhD [KO:K02403]
CNE_BB1p09260  fadA4; 3-ketoacyl-CoA thiolase FadA [KO:K00626] [EC:2.3.1.9]
CNE_BB1p09480  gltL1; glutamate/aspartate ABC transport system ATP-binding protein GltL [KO:K10004] [EC:7.4.2.1]
CNE_BB1p09490  gltK1; glutamate/aspartate ABC transport system permease protein GltK [KO:K10002]
CNE_BB1p09500  gltJ1; glutamate/aspartate ABC transport system permease protein GltJ [KO:K10003]
CNE_BB1p09510  gltI2; glutamate/aspartate ABC transport system permease protein GltI [KO:K10001]
CNE_BB1p09800  [KO:K01644] [EC:4.1.3.34]
CNE_BB1p09930  gltK2; glutamate/aspartate ABC transport system permease protein GltK [KO:K10002]
CNE_BB1p09940  gltJ2; glutamate/aspartate ABC transport system permease protein GltJ [KO:K10003]
CNE_BB1p09950  gltI3; glutamate/aspartate ABC transport system permease protein GltI [KO:K10001]
CNE_BB1p09960  gltL2; glutamate/aspartate ABC transport system ATP-binding protein GltL [KO:K10004] [EC:7.4.2.1]
CNE_BB1p10040  dctA2; C4-dicarboxylate transport protein DctA [KO:K11103]
CNE_BB1p10060  dctA3; C4-dicarboxylate transport protein DctA [KO:K11103]
CNE_BB1p11060  phaA; acetyl-CoA acetyltransferase PhaA [KO:K00626] [EC:2.3.1.9]
CNE_BB1p11190  [KO:K00626] [EC:2.3.1.9]
CNE_BB1p13480  solI; acyl-homoserine-lactone synthase SolI [KO:K13061] [EC:2.3.1.184]
CNE_BB1p14010  [KO:K08738]
CNE_BB1p14030  [KO:K12340]
CNE_BB2p01320  thlA; acetyl-CoA acetyltransferase ThlA [KO:K00626] [EC:2.3.1.9]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00022  Pyruvate
C00025  L-Glutamate
C00031  D-Glucose
C00034  Manganese
C00036  Oxaloacetate
C00038  Zinc cation
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00070  Copper
C00088  Nitrite
C00092  D-Glucose 6-phosphate
C00122  Fumarate
C00149  (S)-Malate
C00158  Citrate
C00164  Acetoacetate
C00237  CO
C00238  Potassium cation
C00244  Nitrate
C00282  Hydrogen
C00291  Nickel
C00305  Magnesium cation
C00399  Ubiquinone
C00533  Nitric oxide
C00547  L-Noradrenaline
C00697  Nitrogen
C00788  L-Adrenaline
C00828  Menaquinone
C01019  L-Fucose
C01104  Trimethylamine N-oxide
C01667  Bacitracin
C02084  Tetrathionate
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05818  2-Demethylmenaquinone
C06230  Fe-enterobactin
C06689  Vancomycin
C06696  Lead
C11612  Polymyxin B
C11842  N-(3-(S)-Hydroxybutyryl)homoserine lactone
C11849  3-Hydroxy-palmitic acid methyl ester
C12008  Ramoplanin A2
C13768  Colistin sulfate
C14819  Fe3+
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C16665  12-Methyltetradecanoic acid
C18206  cis-11-Methyl-2-dodecenoic acid
C21220  AIP-1
C21221  CSP
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21245  AgrD1 peptide
D07746  Colistin (INN)
D08401  Polymyxin B (INN)
Reference
  Authors
Yamamoto K, Hirao K, Oshima T, Aiba H, Utsumi R, Ishihama A.
  Title
Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli.
  Journal
J Biol Chem 280:1448-56 (2005)
DOI:10.1074/jbc.M410104200
Reference
  Authors
Abdel-Fattah WR, Chen Y, Eldakak A, Hulett FM.
  Title
Bacillus subtilis phosphorylated PhoP: direct activation of the E(sigma)A- and repression of the E(sigma)E-responsive phoB-PS+V promoters during pho response.
  Journal
J Bacteriol 187:5166-78 (2005)
DOI:10.1128/JB.187.15.5166-5178.2005
Reference
  Authors
Navarre WW, Halsey TA, Walthers D, Frye J, McClelland M, Potter JL, Kenney LJ, Gunn JS, Fang FC, Libby SJ.
  Title
Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ.
  Journal
Mol Microbiol 56:492-508 (2005)
DOI:10.1111/j.1365-2958.2005.04553.x
Reference
  Authors
Cai SJ, Inouye M.
  Title
EnvZ-OmpR interaction and osmoregulation in Escherichia coli.
  Journal
J Biol Chem 277:24155-61 (2002)
DOI:10.1074/jbc.M110715200
Reference
  Authors
Batchelor E, Walthers D, Kenney LJ, Goulian M.
  Title
The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC.
  Journal
J Bacteriol 187:5723-31 (2005)
DOI:10.1128/JB.187.16.5723-5731.2005
Reference
  Authors
Nagakubo S, Nishino K, Hirata T, Yamaguchi A.
  Title
The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC.
  Journal
J Bacteriol 184:4161-7 (2002)
DOI:10.1128/JB.184.15.4161-4167.2002
Reference
  Authors
Hagiwara D, Yamashino T, Mizuno T.
  Title
A Genome-wide view of the Escherichia coli BasS-BasR two-component system implicated in iron-responses.
  Journal
Biosci Biotechnol Biochem 68:1758-67 (2004)
DOI:10.1271/bbb.68.1758
Reference
  Authors
Munson GP, Lam DL, Outten FW, O'Halloran TV.
  Title
Identification of a copper-responsive two-component system on the chromosome of Escherichia coli K-12.
  Journal
J Bacteriol 182:5864-71 (2000)
DOI:10.1128/JB.182.20.5864-5871.2000
Reference
  Authors
Sperandio V, Torres AG, Kaper JB.
  Title
Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli.
  Journal
Mol Microbiol 43:809-21 (2002)
DOI:10.1046/j.1365-2958.2002.02803.x
Reference
  Authors
Epstein W.
  Title
The roles and regulation of potassium in bacteria.
  Journal
Prog Nucleic Acid Res Mol Biol 75:293-320 (2003)
DOI:10.1016/S0079-6603(03)75008-9
Reference
  Authors
Ansaldi M, Simon G, Lepelletier M, Mejean V.
  Title
The TorR high-affinity binding site plays a key role in both torR autoregulation and torCAD operon expression in Escherichia coli.
  Journal
J Bacteriol 182:961-6 (2000)
DOI:10.1128/JB.182.4.961-966.2000
Reference
  Authors
Malpica R, Franco B, Rodriguez C, Kwon O, Georgellis D.
  Title
Identification of a quinone-sensitive redox switch in the ArcB sensor kinase.
  Journal
Proc Natl Acad Sci U S A 101:13318-23 (2004)
DOI:10.1073/pnas.0403064101
Reference
PMID:2666399
  Authors
Widenhorn KA, Somers JM, Kay WW.
  Title
Genetic regulation of the tricarboxylate transport operon (tctI) of Salmonella typhimurium.
  Journal
J Bacteriol 171:4436-41 (1989)
DOI:10.1128/JB.171.8.4436-4441.1989
Reference
  Authors
Hyyrylainen HL, Bolhuis A, Darmon E, Muukkonen L, Koski P, Vitikainen M, Sarvas M, Pragai Z, Bron S, van Dijl JM, Kontinen VP.
  Title
A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress.
  Journal
Mol Microbiol 41:1159-72 (2001)
DOI:10.1046/j.1365-2958.2001.02576.x
Reference
  Authors
Zhang X, Hulett FM.
  Title
ResD signal transduction regulator of aerobic respiration in Bacillus subtilis: ctaA promoter regulation.
  Journal
Mol Microbiol 37:1208-19 (2000)
DOI:10.1046/j.1365-2958.2000.02076.x
Reference
  Authors
Senadheera MD, Guggenheim B, Spatafora GA, Huang YC, Choi J, Hung DC, Treglown JS, Goodman SD, Ellen RP, Cvitkovitch DG.
  Title
A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence development.
  Journal
J Bacteriol 187:4064-76 (2005)
DOI:10.1128/JB.187.12.4064-4076.2005
Reference
  Authors
He H, Zahrt TC.
  Title
Identification and characterization of a regulatory sequence recognized by Mycobacterium tuberculosis persistence regulator MprA.
  Journal
J Bacteriol 187:202-12 (2005)
DOI:10.1128/JB.187.1.202-212.2005
Reference
  Authors
Hutchings MI
  Title
Unusual two-component signal transduction pathways in the actinobacteria.
  Journal
Adv Appl Microbiol 61:1-26 (2007)
DOI:10.1016/S0065-2164(06)61001-0
Reference
  Authors
Kramer R
  Title
Osmosensing and osmosignaling in Corynebacterium glutamicum.
  Journal
Amino Acids 37:487-97 (2009)
DOI:10.1007/s00726-009-0271-6
Reference
PMID:7751278
  Authors
Eraso JM, Kaplan S.
  Title
Oxygen-insensitive synthesis of the photosynthetic membranes of Rhodobacter sphaeroides: a mutant histidine kinase.
  Journal
J Bacteriol 177:2695-706 (1995)
DOI:10.1128/JB.177.10.2695-2706.1995
Reference
  Authors
Haydel SE, Dunlap NE, Benjamin WH Jr.
  Title
In vitro evidence of two-component system phosphorylation between the Mycobacterium tuberculosis TrcR/TrcS proteins.
  Journal
Microb Pathog 26:195-206 (1999)
DOI:10.1006/mpat.1998.0265
Reference
  Authors
Quisel JD, Burkholder WF, Grossman AD.
  Title
In vivo effects of sporulation kinases on mutant Spo0A proteins in Bacillus subtilis.
  Journal
J Bacteriol 183:6573-8 (2001)
DOI:10.1128/JB.183.22.6573-6578.2001
Reference
  Authors
Kaspar S, Bott M.
  Title
The sensor kinase CitA (DpiB) of Escherichia coli functions as a high-affinity citrate receptor.
  Journal
Arch Microbiol 177:313-21 (2002)
DOI:10.1007/s00203-001-0393-z
Reference
  Authors
Janausch IG, Garcia-Moreno I, Unden G.
  Title
Function of DcuS from Escherichia coli as a fumarate-stimulated histidine protein kinase in vitro.
  Journal
J Biol Chem 277:39809-14 (2002)
DOI:10.1074/jbc.M204482200
Reference
PMID:8550490
  Authors
Brunskill EW, Bayles KW.
  Title
Identification and molecular characterization of a putative regulatory locus that affects autolysis in Staphylococcus aureus.
  Journal
J Bacteriol 178:611-8 (1996)
DOI:10.1128/JB.178.3.611-618.1996
Reference
  Authors
Fujimoto DF, Brunskill EW, Bayles KW.
  Title
Analysis of genetic elements controlling Staphylococcus aureus lrgAB expression: potential role of DNA topology in SarA regulation.
  Journal
J Bacteriol 182:4822-8 (2000)
DOI:10.1128/JB.182.17.4822-4828.2000
Reference
  Authors
Dufour P, Jarraud S, Vandenesch F, Greenland T, Novick RP, Bes M, Etienne J, Lina G.
  Title
High genetic variability of the agr locus in Staphylococcus species.
  Journal
J Bacteriol 184:1180-6 (2002)
DOI:10.1128/JB.184.4.1180-1186.2002
Reference
PMID:8501030
  Authors
Rabin RS, Stewart V.
  Title
Dual response regulators (NarL and NarP) interact with dual sensors (NarX and NarQ) to control nitrate- and nitrite-regulated gene expression in Escherichia coli K-12.
  Journal
J Bacteriol 175:3259-68 (1993)
DOI:10.1128/JB.175.11.3259-3268.1993
Reference
PMID:9220011
  Authors
Chiang RC, Cavicchioli R, Gunsalus RP.
  Title
'Locked-on' and 'locked-off' signal transduction mutations in the periplasmic domain of the Escherichia coli NarQ and NarX sensors affect nitrate- and nitrite-dependent regulation by NarL and NarP.
  Journal
Mol Microbiol 24:1049-60 (1997)
DOI:10.1046/j.1365-2958.1997.4131779.x
Reference
  Authors
Verhamme DT, Postma PW, Crielaard W, Hellingwerf KJ.
  Title
Cooperativity in signal transfer through the Uhp system of Escherichia coli.
  Journal
J Bacteriol 184:4205-10 (2002)
DOI:10.1128/JB.184.15.4205-4210.2002
Reference
  Authors
Hagiwara D, Sugiura M, Oshima T, Mori H, Aiba H, Yamashino T, Mizuno T.
  Title
Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli.
  Journal
J Bacteriol 185:5735-46 (2003)
DOI:10.1128/JB.185.19.5735-5746.2003
Reference
  Authors
Hirakawa H, Nishino K, Yamada J, Hirata T, Yamaguchi A.
  Title
Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli.
  Journal
J Antimicrob Chemother 52:576-82 (2003)
DOI:10.1093/jac/dkg406
Reference
  Authors
Suzuki K, Wang X, Weilbacher T, Pernestig AK, Melefors O, Georgellis D, Babitzke P, Romeo T.
  Title
Regulatory circuitry of the CsrA/CsrB and BarA/UvrY systems of Escherichia coli.
  Journal
J Bacteriol 184:5130-40 (2002)
DOI:10.1128/JB.184.18.5130-5140.2002
Reference
  Authors
Kato A, Ohnishi H, Yamamoto K, Furuta E, Tanabe H, Utsumi R.
  Title
Transcription of emrKY is regulated by the EvgA-EvgS two-component system in Escherichia coli K-12.
  Journal
Biosci Biotechnol Biochem 64:1203-9 (2000)
DOI:10.1271/bbb.64.1203
Reference
  Authors
Ansaldi M, Dubnau D.
  Title
Diversifying selection at the Bacillus quorum-sensing locus and determinants of modification specificity during synthesis of the ComX pheromone.
  Journal
J Bacteriol 186:15-21 (2004)
DOI:10.1128/JB.186.1.15-21.2004
Reference
  Authors
Gabdrakhmanova L, Vishniakov I, Sharipova M, Balaban N, Kostrov S, Leshchinskaya I.
  Title
Salt stress induction of glutamyl endopeptidase biosynthesis in Bacillus intermedius.
  Journal
Microbiol Res 160:233-42 (2005)
DOI:10.1016/j.micres.2004.05.005
Reference
  Authors
Aguilar PS, Hernandez-Arriaga AM, Cybulski LE, Erazo AC, de Mendoza D.
  Title
Molecular basis of thermosensing: a two-component signal transduction thermometer in Bacillus subtilis.
  Journal
EMBO J 20:1681-91 (2001)
DOI:10.1093/emboj/20.7.1681
Reference
  Authors
Kuroda M, Kuroda H, Oshima T, Takeuchi F, Mori H, Hiramatsu K.
  Title
Two-component system VraSR positively modulates the regulation of cell-wall biosynthesis pathway in Staphylococcus aureus.
  Journal
Mol Microbiol 49:807-21 (2003)
DOI:10.1046/j.1365-2958.2003.03599.x
Reference
  Authors
Saini DK, Malhotra V, Dey D, Pant N, Das TK, Tyagi JS.
  Title
DevR-DevS is a bona fide two-component system of Mycobacterium tuberculosis that is hypoxia-responsive in the absence of the DNA-binding domain of DevR.
  Journal
Microbiology 150:865-75 (2004)
DOI:10.1099/mic.0.26218-0
Reference
  Authors
Fedtke I, Kamps A, Krismer B, Gotz F.
  Title
The nitrate reductase and nitrite reductase operons and the narT gene of Staphylococcus carnosus are positively controlled by the novel two-component system NreBC.
  Journal
J Bacteriol 184:6624-34 (2002)
DOI:10.1128/JB.184.23.6624-6634.2002
Reference
PMID:8416895
  Authors
Shiau SP, Chen P, Reitzer LJ.
  Title
Effects of insertions and deletions in glnG (ntrC) of Escherichia coli on nitrogen regulator I-dependent DNA binding and transcriptional activation.
  Journal
J Bacteriol 175:190-9 (1993)
DOI:10.1128/JB.175.1.190-199.1993
Reference
  Authors
Leonhartsberger S, Huber A, Lottspeich F, Bock A.
  Title
The hydH/G Genes from Escherichia coli code for a zinc and lead responsive two-component regulatory system.
  Journal
J Mol Biol 307:93-105 (2001)
DOI:10.1006/jmbi.2000.4451
Reference
  Authors
Lioliou EE, Kyriakidis DA.
  Title
The role of bacterial antizyme: From an inhibitory protein to AtoC transcriptional regulator.
  Journal
Microb Cell Fact 3:8 (2004)
DOI:10.1186/1475-2859-3-8
Reference
  Authors
Yamamoto K, Ishihama A
  Title
Transcriptional response of Escherichia coli to external copper.
  Journal
Mol Microbiol 56:215-27 (2005)
DOI:10.1111/j.1365-2958.2005.04532.x
Reference
  Authors
Ashby MK, Mullineaux CW
  Title
Cyanobacterial ycf27 gene products regulate energy transfer from phycobilisomes to photosystems I and II.
  Journal
FEMS Microbiol Lett 181:253-60 (1999)
DOI:10.1111/j.1574-6968.1999.tb08852.x
Reference
  Authors
Lopez-Maury L, Garcia-Dominguez M, Florencio FJ, Reyes JC
  Title
A two-component signal transduction system involved in nickel sensing in the cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Mol Microbiol 43:247-56 (2002)
DOI:10.1046/j.1365-2958.2002.02741.x
Reference
  Authors
Glover RT, Kriakov J, Garforth SJ, Baughn AD, Jacobs WR Jr
  Title
The two-component regulatory system senX3-regX3 regulates phosphate-dependent gene expression in Mycobacterium smegmatis.
  Journal
J Bacteriol 189:5495-503 (2007)
DOI:10.1128/JB.00190-07
Reference
  Authors
Hsiao HY, He Q, Van Waasbergen LG, Grossman AR
  Title
Control of photosynthetic and high-light-responsive genes by the histidine kinase DspA: negative and positive regulation and interactions between signal transduction pathways.
  Journal
J Bacteriol 186:3882-8 (2004)
DOI:10.1128/JB.186.12.3882-3888.2004
Reference
  Authors
Mutsuda M, Michel KP, Zhang X, Montgomery BL, Golden SS
  Title
Biochemical properties of CikA, an unusual phytochrome-like histidine protein kinase that resets the circadian clock in Synechococcus elongatus PCC 7942.
  Journal
J Biol Chem 278:19102-10 (2003)
DOI:10.1074/jbc.M213255200
Reference
PMID:9278513
  Authors
Yeh KC, Wu SH, Murphy JT, Lagarias JC
  Title
A cyanobacterial phytochrome two-component light sensory system.
  Journal
Science 277:1505-8 (1997)
DOI:10.1126/science.277.5331.1505
Reference
PMID:7635815
  Authors
Niu S, Jiang SQ, Hong J
  Title
Salmonella typhimurium pgtB mutants conferring constitutive expression of phosphoglycerate transporter pgtP independent of pgtC.
  Journal
J Bacteriol 177:4297-302 (1995)
DOI:10.1128/JB.177.15.4297-4302.1995
Reference
  Authors
Takai N, Nakajima M, Oyama T, Kito R, Sugita C, Sugita M, Kondo T, Iwasaki H
  Title
A KaiC-associating SasA-RpaA two-component regulatory system as a major circadian timing mediator in cyanobacteria.
  Journal
Proc Natl Acad Sci U S A 103:12109-14 (2006)
DOI:10.1073/pnas.0602955103
Reference
  Authors
Janausch IG, Zientz E, Tran QH, Kroger A, Unden G
  Title
C4-dicarboxylate carriers and sensors in bacteria.
  Journal
Biochim Biophys Acta 1553:39-56 (2002)
DOI:10.1016/S0005-2728(01)00233-X
Reference
  Authors
Zhou YF, Nan B, Nan J, Ma Q, Panjikar S, Liang YH, Wang Y, Su XD
  Title
C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain.
  Journal
J Mol Biol 383:49-61 (2008)
DOI:10.1016/j.jmb.2008.08.010
Reference
  Authors
Novick RP, Jiang D
  Title
The staphylococcal saeRS system coordinates environmental signals with agr quorum sensing.
  Journal
Microbiology 149:2709-17 (2003)
DOI:10.1099/mic.0.26575-0
Reference
  Authors
Leech AJ, Sprinkle A, Wood L, Wozniak DJ, Ohman DE
  Title
The NtrC family regulator AlgB, which controls alginate biosynthesis in mucoid Pseudomonas aeruginosa, binds directly to the algD promoter.
  Journal
J Bacteriol 190:581-9 (2008)
DOI:10.1128/JB.01307-07
Reference
  Authors
Paul R, Jaeger T, Abel S, Wiederkehr I, Folcher M, Biondi EG, Laub MT, Jenal U
  Title
Allosteric regulation of histidine kinases by their cognate response regulator determines cell fate.
  Journal
Cell 133:452-61 (2008)
DOI:10.1016/j.cell.2008.02.045
Reference
  Authors
Whitchurch CB, Leech AJ, Young MD, Kennedy D, Sargent JL, Bertrand JJ, Semmler AB, Mellick AS, Martin PR, Alm RA, Hobbs M, Beatson SA, Huang B, Nguyen L, Commolli JC, Engel JN, Darzins A, Mattick JS.
  Title
Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa.
  Journal
Mol Microbiol 52:873-93 (2004)
DOI:10.1111/j.1365-2958.2004.04026.x
Reference
  Authors
Yoshihara S, Ikeuchi M.
  Title
Phototactic motility in the unicellular cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Photochem Photobiol Sci 3:512-8 (2004)
DOI:10.1039/b402320j
Reference
  Authors
Ogawa T, Bao DH, Katoh H, Shibata M, Pakrasi HB, Bhattacharyya-Pakrasi M
  Title
A two-component signal transduction pathway regulates manganese homeostasis in Synechocystis 6803, a photosynthetic organism.
  Journal
J Biol Chem 277:28981-6 (2002)
DOI:10.1074/jbc.M204175200
Reference
  Authors
Yamaguchi K, Suzuki I, Yamamoto H, Lyukevich A, Bodrova I, Los DA, Piven I, Zinchenko V, Kanehisa M, Murata N
  Title
A two-component Mn2+-sensing system negatively regulates expression of the mntCAB operon in Synechocystis.
  Journal
Plant Cell 14:2901-13 (2002)
DOI:10.1105/tpc.006262
Reference
  Authors
Mascher T, Zimmer SL, Smith TA, Helmann JD
  Title
Antibiotic-inducible promoter regulated by the cell envelope stress-sensing two-component system LiaRS of Bacillus subtilis.
  Journal
Antimicrob Agents Chemother 48:2888-96 (2004)
DOI:10.1128/AAC.48.8.2888-2896.2004
Reference
  Authors
Hyyrylainen HL, Sarvas M, Kontinen VP
  Title
Transcriptome analysis of the secretion stress response of Bacillus subtilis.
  Journal
Appl Microbiol Biotechnol 67:389-96 (2005)
DOI:10.1007/s00253-005-1898-1
Reference
  Authors
Serizawa M, Sekiguchi J
  Title
The Bacillus subtilis YdfHI two-component system regulates the transcription of ydfJ, a member of the RND superfamily.
  Journal
Microbiology 151:1769-78 (2005)
DOI:10.1099/mic.0.27619-0
Reference
  Authors
Ohki R, Giyanto, Tateno K, Masuyama W, Moriya S, Kobayashi K, Ogasawara N
  Title
The BceRS two-component regulatory system induces expression of the bacitracin transporter, BceAB, in Bacillus subtilis.
  Journal
Mol Microbiol 49:1135-44 (2003)
DOI:10.1046/j.1365-2958.2003.03653.x
Reference
  Authors
Ogura M, Tsukahara K, Hayashi K, Tanaka T
  Title
The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion.
  Journal
Microbiology 153:667-75 (2007)
DOI:10.1099/mic.0.2006/003673-0
Reference
  Authors
Yamamoto H, Murata M, Sekiguchi J
  Title
The CitST two-component system regulates the expression of the Mg-citrate transporter in Bacillus subtilis.
  Journal
Mol Microbiol 37:898-912 (2000)
DOI:10.1046/j.1365-2958.2000.02055.x
Reference
  Authors
Satomura T, Shimura D, Asai K, Sadaie Y, Hirooka K, Fujita Y
  Title
Enhancement of glutamine utilization in Bacillus subtilis through the GlnK-GlnL two-component regulatory system.
  Journal
J Bacteriol 187:4813-21 (2005)
DOI:10.1128/JB.187.14.4813-4821.2005
Reference
  Authors
Doan T, Servant P, Tojo S, Yamaguchi H, Lerondel G, Yoshida K, Fujita Y, Aymerich S
  Title
The Bacillus subtilis ywkA gene encodes a malic enzyme and its transcription is activated by the YufL/YufM two-component system in response to malate.
  Journal
Microbiology 149:2331-43 (2003)
DOI:10.1099/mic.0.26256-0
Reference
  Authors
Tanaka K, Kobayashi K, Ogasawara N
  Title
The Bacillus subtilis YufLM two-component system regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium.
  Journal
Microbiology 149:2317-29 (2003)
DOI:10.1099/mic.0.26257-0
Reference
  Authors
Asai K, Baik SH, Kasahara Y, Moriya S, Ogasawara N
  Title
Regulation of the transport system for C4-dicarboxylic acids in Bacillus subtilis.
  Journal
Microbiology 146 ( Pt 2):263-71 (2000)
DOI:10.1099/00221287-146-2-263
Reference
PMID:8455557
  Authors
Hamblin MJ, Shaw JG, Kelly DJ
  Title
Sequence analysis and interposon mutagenesis of a sensor-kinase (DctS) and response-regulator (DctR) controlling synthesis of the high-affinity C4-dicarboxylate transport system in Rhodobacter capsulatus.
  Journal
Mol Gen Genet 237:215-24 (1993)
DOI:10.1007/BF00282803
Reference
PMID:9287004
  Authors
Forward JA, Behrendt MC, Wyborn NR, Cross R, Kelly DJ
  Title
TRAP transporters: a new family of periplasmic solute transport systems encoded by the dctPQM genes of Rhodobacter capsulatus and by homologs in diverse gram-negative bacteria.
  Journal
J Bacteriol 179:5482-93 (1997)
DOI:10.1128/JB.179.17.5482-5493.1997
Reference
  Authors
Martin B, Quentin Y, Fichant G, Claverys JP
  Title
Independent evolution of competence regulatory cascades in streptococci?
  Journal
Trends Microbiol 14:339-45 (2006)
DOI:10.1016/j.tim.2006.06.007
Reference
  Authors
Hensel M, Hinsley AP, Nikolaus T, Sawers G, Berks BC
  Title
The genetic basis of tetrathionate respiration in Salmonella typhimurium.
  Journal
Mol Microbiol 32:275-87 (1999)
DOI:10.1046/j.1365-2958.1999.01345.x
Reference
  Authors
Guvener ZT, Harwood CS
  Title
Subcellular location characteristics of the Pseudomonas aeruginosa GGDEF protein, WspR, indicate that it produces cyclic-di-GMP in response to growth on surfaces.
  Journal
Mol Microbiol 66:1459-73 (2007)
DOI:10.1111/j.1365-2958.2007.06008.x
Reference
  Authors
Bantinaki E, Kassen R, Knight CG, Robinson Z, Spiers AJ, Rainey PB
  Title
Adaptive divergence in experimental populations of Pseudomonas fluorescens. III. Mutational origins of wrinkly spreader diversity.
  Journal
Genetics 176:441-53 (2007)
DOI:10.1534/genetics.106.069906
Reference
  Authors
Jiang M, Shao W, Perego M, Hoch JA
  Title
Multiple histidine kinases regulate entry into stationary phase and sporulation in Bacillus subtilis.
  Journal
Mol Microbiol 38:535-42 (2000)
DOI:10.1046/j.1365-2958.2000.02148.x
Reference
  Authors
Jenal U
  Title
The role of proteolysis in the Caulobacter crescentus cell cycle and development.
  Journal
Res Microbiol 160:687-95 (2009)
DOI:10.1016/j.resmic.2009.09.006
Reference
  Authors
Jenal U, Galperin MY
  Title
Single domain response regulators: molecular switches with emerging roles in cell organization and dynamics.
  Journal
Curr Opin Microbiol 12:152-60 (2009)
DOI:10.1016/j.mib.2009.01.010
Reference
  Authors
Drepper T, Wiethaus J, Giaourakis D, Gross S, Schubert B, Vogt M, Wiencek Y, McEwan AG, Masepohl B
  Title
Cross-talk towards the response regulator NtrC controlling nitrogen metabolism in Rhodobacter capsulatus.
  Journal
FEMS Microbiol Lett 258:250-6 (2006)
DOI:10.1111/j.1574-6968.2006.00228.x
Reference
PMID:1661370
  Authors
Pawlowski K, Klosse U, de Bruijn FJ
  Title
Characterization of a novel Azorhizobium caulinodans ORS571 two-component regulatory system, NtrY/NtrX, involved in nitrogen fixation and metabolism.
  Journal
Mol Gen Genet 231:124-38 (1991)
DOI:10.1007/BF00293830
Reference
  Authors
Chatterjee S, Almeida RP, Lindow S
  Title
Living in two worlds: the plant and insect lifestyles of Xylella fastidiosa.
  Journal
Annu Rev Phytopathol 46:243-71 (2008)
DOI:10.1146/annurev.phyto.45.062806.094342
Reference
  Authors
Dow M
  Title
Diversification of the function of cell-to-cell signaling in regulation of virulence within plant pathogenic xanthomonads.
  Journal
Sci Signal 1:pe23 (2008)
DOI:10.1126/stke.121pe23
Reference
  Authors
Colnaghi Simionato AV, da Silva DS, Lambais MR, Carrilho E
  Title
Characterization of a putative Xylella fastidiosa diffusible signal factor by HRGC-EI-MS.
  Journal
J Mass Spectrom 42:1375-81 (2007)
DOI:10.1002/jms.1325
Reference
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
DOI:10.1016/S0065-2164(08)00803-4
Reference
PMID:8760916
  Authors
Eder S, Shi L, Jensen K, Yamane K, Hulett FM
  Title
A Bacillus subtilis secreted phosphodiesterase/alkaline phosphatase is the product of a Pho regulon gene, phoD.
  Journal
Microbiology 142 ( Pt 8):2041-7 (1996)
DOI:10.1099/13500872-142-8-2041
Related
pathway
cnc00190  Oxidative phosphorylation
cnc00550  Peptidoglycan biosynthesis
cnc00910  Nitrogen metabolism
cnc02030  Bacterial chemotaxis
cnc02040  Flagellar assembly
cnc03070  Bacterial secretion system
KO pathway
ko02020   

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