KEGG   PATHWAY: csin04148
Entry
csin04148                   Pathway                                
Name
Efferocytosis - Camellia sinensis (tea plant)
Class
Cellular Processes; Transport and catabolism
Pathway map
csin04148  Efferocytosis
csin04148

Organism
Camellia sinensis (tea plant) [GN:csin]
Gene
114255928  [KO:K01052] [EC:3.1.1.13]
114256394  [KO:K20179]
114256984  [KO:K07897]
114257851  [KO:K00411] [EC:7.1.1.8]
114258337  [KO:K04459] [EC:3.1.3.16 3.1.3.48]
114259432  [KO:K07887]
114259550  [KO:K04392]
114260176  [KO:K01581] [EC:4.1.1.17]
114260833  [KO:K04718] [EC:2.7.1.91]
114260872  [KO:K20181]
114261521  [KO:K00411] [EC:7.1.1.8]
114261766  [KO:K08057]
114261968  [KO:K23678]
114262439  [KO:K17398] [EC:2.1.1.37]
114264491  [KO:K07897]
114265211  [KO:K01581] [EC:4.1.1.17]
114265869  [KO:K07887]
114267492  [KO:K26935]
114267565  [KO:K07887]
114269678  [KO:K26935]
114271589  [KO:K20177]
114272879  [KO:K14802] [EC:7.6.2.1]
114273390  [KO:K05853] [EC:7.2.2.10]
114273719  [KO:K20184]
114274283  [KO:K07897]
114274539  [KO:K08057]
114275343  [KO:K07897]
114275387  [KO:K20180]
114275658  [KO:K20178]
114276952  [KO:K20184]
114278006  [KO:K26935]
114278523  [KO:K20181]
114278678  [KO:K20180]
114279323  [KO:K04392]
114279716  [KO:K01052] [EC:3.1.1.13]
114279726  [KO:K01052] [EC:3.1.1.13]
114279753  [KO:K01052] [EC:3.1.1.13]
114279755  [KO:K01052] [EC:3.1.1.13]
114279880  [KO:K04392]
114281718  [KO:K20181]
114282376  [KO:K04392]
114284986  [KO:K23678]
114285325  [KO:K04368] [EC:2.7.12.2]
114285576  [KO:K04371] [EC:2.7.11.24]
114285903  [KO:K07897]
114286067  [KO:K26935]
114286551  [KO:K01052] [EC:3.1.1.13]
114286707  [KO:K14802] [EC:7.6.2.1]
114286995  [KO:K05853] [EC:7.2.2.10]
114288825  [KO:K07897]
114293566  [KO:K07897]
114293916  [KO:K14802] [EC:7.6.2.1]
114294841  [KO:K07887]
114294869  [KO:K14802] [EC:7.6.2.1]
114295171  [KO:K26935]
114296037  [KO:K01581] [EC:4.1.1.17]
114297258  [KO:K04392]
114298374  [KO:K07887]
114299349  [KO:K20182]
114300940  [KO:K07897]
114301257  [KO:K20184]
114301734  [KO:K04392]
114302398  [KO:K23678]
114303735  [KO:K07897]
114303964  [KO:K04392]
114305515  [KO:K08057]
114305555  [KO:K01476] [EC:3.5.3.1]
114308484  [KO:K07897]
114308643  [KO:K07887]
114309402  [KO:K04392]
114309465  [KO:K04459] [EC:3.1.3.16 3.1.3.48]
114310011  [KO:K08057]
114311386  [KO:K04392]
114313042  [KO:K17398] [EC:2.1.1.37]
114313131  [KO:K17398] [EC:2.1.1.37]
114313679  [KO:K01476] [EC:3.5.3.1]
114315148  [KO:K20183]
114316956  [KO:K07897]
114317191  [KO:K04392]
114317467  [KO:K04392]
114318044  [KO:K23678]
114320960  [KO:K14802] [EC:7.6.2.1]
114321005  [KO:K01052] [EC:3.1.1.13]
114321297  [KO:K04392]
114322619  [KO:K07887]
Compound
C00002  ATP
C00003  NAD+
C00019  S-Adenosyl-L-methionine
C00031  D-Glucose
C00062  L-Arginine
C00073  L-Methionine
C00075  UTP
C00077  L-Ornithine
C00134  Putrescine
C00162  Fatty acid
C00186  (S)-Lactate
C00187  Cholesterol
C00584  Prostaglandin E2
C02530  Cholesterol ester
C02737  Phosphatidylserine
C04230  1-Acyl-sn-glycero-3-phosphocholine
C06124  Sphingosine 1-phosphate
C06314  Lipoxin A4
C15519  25-Hydroxycholesterol
C15610  Cholest-5-ene-3beta,26-diol
C18178  Resolvin D1
Reference
PMID:31822793
  Authors
Doran AC, Yurdagul A Jr, Tabas I
  Title
Efferocytosis in health and disease.
  Journal
Nat Rev Immunol 20:254-267 (2020)
DOI:10.1038/s41577-019-0240-6
Reference
PMID:36028471
  Authors
Zhang J, Ding W, Zhao M, Liu J, Xu Y, Wan J, Wang M
  Title
Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease.
  Journal
Br J Pharmacol 179:5151-5171 (2022)
DOI:10.1111/bph.15939
Reference
PMID:30165442
  Authors
Kawano M, Nagata S
  Title
Efferocytosis and autoimmune disease.
  Journal
Int Immunol 30:551-558 (2018)
DOI:10.1093/intimm/dxy055
Reference
PMID:35650427
  Authors
Mehrotra P, Ravichandran KS
  Title
Drugging the efferocytosis process: concepts and opportunities.
  Journal
Nat Rev Drug Discov 21:601-620 (2022)
DOI:10.1038/s41573-022-00470-y
Reference
PMID:28496201
  Authors
Park SY, Kim IS
  Title
Engulfment signals and the phagocytic machinery for apoptotic cell clearance.
  Journal
Exp Mol Med 49:e331 (2017)
DOI:10.1038/emm.2017.52
Reference
PMID:28137963
  Authors
Kojima Y, Weissman IL, Leeper NJ
  Title
The Role of Efferocytosis in Atherosclerosis.
  Journal
Circulation 135:476-489 (2017)
DOI:10.1161/CIRCULATIONAHA.116.025684
Related
pathway
csin00010  Glycolysis / Gluconeogenesis
csin04145  Phagocytosis
KO pathway
ko04148   

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