KEGG   MODULE: dru_M00011
Entry
dru_M00011        Pathway   Module                                 
Name
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Definition
((K00164+K00658,K01616)+K00382,K00174+K00175-K00177-K00176) (K01902+K01903,K01899+K01900,K18118) (K00234+K00235+K00236+(K00237,K25801),K00239+K00240+K00241-(K00242,K18859,K18860),K00244+K00245+K00246-K00247) (K01676,K01679,K01677+K01678) (K00026,K00025,K00024,K00116)
Diagram
dru_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
dru_M00011

Class
Pathway modules; Carbohydrate metabolism; Central carbohydrate metabolism
Pathway
dru00020  Citrate cycle (TCA cycle)
dru01200  Carbon metabolism
dru01210  2-Oxocarboxylic acid metabolism
dru01100  Metabolic pathways
Organism
Desulforamulus ruminis [GN:dru]
Gene
Desru_0099  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00174]
Desru_0100  thiamine pyrophosphate TPP-binding domain-containing protein [KO:K00175]
Desru_0101  pyruvate/ketoisovalerate oxidoreductase, gamma subunit [KO:K00177]
Desru_0102  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein [KO:K00176]
Desru_1663  dihydrolipoamide dehydrogenase [KO:K00382]
Desru_2002  hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit [KO:K01677]
Desru_2003  hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit [KO:K01678]
Desru_2005  succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family [KO:K00241]
Desru_2006  succinate dehydrogenase or fumarate reductase, flavoprotein subunit [KO:K00239]
Desru_2007  succinate dehydrogenase and fumarate reductase iron-sulfur protein [KO:K00240]
Desru_2008  malate dehydrogenase, NAD-dependent [KO:K00024]
Desru_2252  succinyl-CoA synthetase, alpha subunit [KO:K01902]
Desru_2253  succinyl-CoA synthetase, beta subunit [KO:K01903]
Desru_2275  Pyruvate/ketoisovalerate oxidoreductase, catalytic domain protein [KO:K00177]
Desru_2276  2-oxoglutarate synthase [KO:K00175]
Desru_2277  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00174]
Desru_2278  4Fe-4S ferredoxin iron-sulfur binding domain protein [KO:K00176]
Desru_2485  dihydrolipoamide dehydrogenase [KO:K00382]
Desru_3045  pyruvate/ketoisovalerate oxidoreductase, gamma subunit [KO:K00177]
Desru_3046  thiamine pyrophosphate TPP-binding domain-containing protein [KO:K00175]
Desru_3047  3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) [KO:K00174]
Desru_3048  ferredoxin [KO:K00176]
Desru_3401  dihydrolipoamide dehydrogenase [KO:K00382]
Desru_3836  Succinate--CoA ligase (ADP-forming) [KO:K01903]
Desru_3837  Succinate--CoA ligase (ADP-forming) [KO:K01902]
Reaction
R00621+R03316,R01700  
R02570  
R07618  
R01197  
R00405,R00432,R00727,R10343  
R02164  
R01082  
R00342,R00361  
Compound
C00026  2-Oxoglutarate
C15972  Enzyme N6-(lipoyl)lysine
C16254  [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine
C00091  Succinyl-CoA
C15973  Enzyme N6-(dihydrolipoyl)lysine
C00042  Succinate
C00122  Fumarate
C00149  (S)-Malate
C00036  Oxaloacetate
RModule
RM044  2-Oxocarboxylic acid conversion to its CoA derivative
KO module
M00011
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