KEGG   PATHWAY: gaf00190
Entry
gaf00190                    Pathway                                
Name
Oxidative phosphorylation - Gambusia affinis (western mosquitofish)
Class
Metabolism; Energy metabolism
Pathway map
gaf00190  Oxidative phosphorylation
gaf00190

Module
gaf_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:gaf00190]
gaf_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:gaf00190]
gaf_M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:gaf00190]
gaf_M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:gaf00190]
gaf_M00148  Succinate dehydrogenase (ubiquinone) [PATH:gaf00190]
gaf_M00151  Cytochrome bc1 complex respiratory unit [PATH:gaf00190]
gaf_M00152  Cytochrome bc1 complex [PATH:gaf00190]
gaf_M00154  Cytochrome c oxidase [PATH:gaf00190]
gaf_M00160  V-type ATPase, eukaryotes [PATH:gaf00190]
Organism
Gambusia affinis (western mosquitofish) [GN:gaf]
Gene
805456  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
805450  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
805455  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
805445  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
805452  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
805451  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
805444  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
122826865  ndufs1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial [KO:K03934] [EC:7.1.1.2]
122839642  NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial-like [KO:K03934] [EC:7.1.1.2]
122820504  ndufs2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935] [EC:7.1.1.2]
122845001  ndufs3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1 [KO:K03936] [EC:7.1.1.2]
122828641  ndufs4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937]
122843383  ndufs5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
122843453  ndufs6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial isoform X1 [KO:K03939]
122839100  ndufs7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial [KO:K03940] [EC:7.1.1.2]
122836681  NADH-ubiquinone oxidoreductase subunit 8-like isoform X1 [KO:K03941] [EC:7.1.1.2]
122829157  NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial-like [KO:K03941] [EC:7.1.1.2]
122830563  NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial-like isoform X1 [KO:K03942] [EC:7.1.1.2]
122840876  ndufv2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
122839907  ndufv3; uncharacterized protein ndufv3 isoform X1 [KO:K03944]
122837488  ndufa1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
122844812  ndufa2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
122830554  ndufa3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
122823556  cytochrome c oxidase subunit NDUFA4-like [KO:K03948]
122833823  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
122821942  ndufa4a; cytochrome c oxidase subunit NDUFA4L [KO:K03948]
122839975  ndufa4l2a; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
122826061  ndufa5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
122822151  ndufa6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
122838853  ndufa7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
122847238  ndufa8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
122835128  ndufa9a; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
122840203  ndufa10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
122822278  ndufab1b; NADH:ubiquinone oxidoreductase subunit AB1b [KO:K03955]
122838367  ndufa11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
122826222  ndufa12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
122840990  ndufa13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
122825054  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1-like [KO:K03957]
122826615  ndufb2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial isoform X1 [KO:K03958]
122840739  ndufb3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959]
122823905  ndufb4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
122838671  ndufb5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
122829440  ndufb6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
122829704  ndufb7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
122823107  ndufb8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
122844123  ndufb9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform X1 [KO:K03965]
122822491  ndufb10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
122830177  ndufb11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
122836569  ndufc1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
122832674  ndufc2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
122831522  sdha; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [KO:K00234] [EC:1.3.5.1]
122834598  sdhb; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
122835847  succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial-like [KO:K00235] [EC:1.3.5.1]
122841487  sdhc; succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1 [KO:K00236]
122833312  sdhdb; succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial [KO:K00237]
122846824  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
122836257  cytochrome b-c1 complex subunit Rieske, mitochondrial-like [KO:K00411] [EC:7.1.1.8]
805449  CYTB; cytochrome b [KO:K00412]
122834571  cytochrome c1, heme protein, mitochondrial [KO:K00413]
122834378  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
122823713  cytochrome b-c1 complex subunit 2, mitochondrial isoform X1 [KO:K00415]
122821813  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
122838034  cytochrome b-c1 complex subunit 6, mitochondrial-like [KO:K00416]
122840538  cytochrome b-c1 complex subunit 6, mitochondrial-like [KO:K00416]
122843288  cytochrome b-c1 complex subunit 7 [KO:K00417]
122837371  cytochrome b-c1 complex subunit 8 isoform X1 [KO:K00418]
122847165  cytochrome b-c1 complex subunit 9 [KO:K00419]
122841548  cytochrome b-c1 complex subunit 10 [KO:K00420]
122839027  cytochrome b-c1 complex subunit 10-like [KO:K00420]
122823117  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
805446  COX3; cytochrome c oxidase subunit III [KO:K02262]
805447  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
805448  COX2; cytochrome c oxidase subunit II [KO:K02261]
122830648  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
122843022  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
122840672  cytochrome c oxidase subunit 5A, mitochondrial-like [KO:K02264]
122836239  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
122846962  cytochrome c oxidase subunit 5B, mitochondrial-like [KO:K02265]
122819281  cytochrome c oxidase subunit 5B, mitochondrial-like [KO:K02265]
122842775  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
122828294  cytochrome c oxidase subunit 6A, mitochondrial [KO:K02266]
122822643  cytochrome c oxidase subunit 6A, mitochondrial [KO:K02266]
122830476  cytochrome c oxidase subunit 6B1 [KO:K02267]
122843318  cytochrome c oxidase subunit 6B1-like [KO:K02267]
122822806  cytochrome c oxidase subunit 6B1 [KO:K02267]
122834075  cytochrome c oxidase subunit 6C-1 [KO:K02268]
122823814  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
122825559  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
122833293  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
122844768  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
122826171  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
122846541  cytochrome c oxidase subunit 8A, mitochondrial-like [KO:K02273]
122825307  si:dkey-85n7.8; COX8 domain-containing protein [KO:K02273]
122823043  cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
122842290  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
122840107  cytochrome c oxidase copper chaperone [KO:K02260]
122839963  cytochrome c-b-like [KO:K08738]
122839964  cytochrome c-b [KO:K08738]
122842717  cytochrome c [KO:K08738]
122843364  cytochrome c iso-1/iso-2-like [KO:K08738]
122846815  atp5fa1; ATP synthase subunit alpha, mitochondrial [KO:K02132]
122827659  ATP synthase subunit alpha, mitochondrial-like [KO:K02132]
122827417  atp5f1b; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
122826735  atp5f1c; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
122838993  atp5f1d; ATP synthase subunit delta, mitochondrial [KO:K02134]
122840009  atp5f1e; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
122837592  atp5po; ATP synthase subunit O, mitochondrial [KO:K02137]
805454  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
122834049  atp5pb; ATP synthase F(0) complex subunit B1, mitochondrial isoform X1 [KO:K02127]
122840187  atp5mc3a; ATP synthase membrane subunit c locus 3a [KO:K02128]
122822567  ATP synthase F(0) complex subunit C3, mitochondrial-like [KO:K02128]
122829762  atp5pd; ATP synthase subunit d, mitochondrial [KO:K02138]
122822209  atp5mf; ATP synthase subunit f, mitochondrial [KO:K02130]
122844967  ATP synthase subunit g, mitochondrial-like [KO:K02140]
122841062  ATP synthase subunit g, mitochondrial-like [KO:K02140]
122827196  atp5pf; ATP synthase-coupling factor 6, mitochondrial [KO:K02131]
805453  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
122844473  V-type proton ATPase catalytic subunit A-like [KO:K02145] [EC:7.1.2.2]
122824629  atp6v1ab; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:7.1.2.2]
122847204  V-type proton ATPase subunit B, brain isoform-like [KO:K02147]
122842286  atp6v1ba; V-type proton ATPase subunit B, kidney isoform [KO:K02147]
122845619  atp6v1c2; V-type proton ATPase subunit C 1-B [KO:K02148]
122831160  atp6v1c1a; V-type proton ATPase subunit C 1-A [KO:K02148]
122843488  atp6v1c1b; V-type proton ATPase subunit C 1-B [KO:K02148]
122825719  atp6v1d; V-type proton ATPase subunit D [KO:K02149]
122826206  atp6v1e1b; V-type proton ATPase subunit E 1 [KO:K02150]
122835134  atp6v1e1a; V-type proton ATPase subunit E 1a isoform X1 [KO:K02150]
122826645  atp6v1f; V-type proton ATPase subunit F [KO:K02151]
122819599  atp6v1g1; V-type proton ATPase subunit G 1 [KO:K02152]
122840794  atp6v1h; V-type proton ATPase subunit H isoform X1 [KO:K02144]
122846877  atp6v0a2a; V-type proton ATPase 116 kDa subunit a2 [KO:K02154]
122823238  V-type proton ATPase 116 kDa subunit a1-like isoform X1 [KO:K02154]
122837632  tcirg1b; T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b [KO:K02154]
122828088  atp6v0a2b; V-type proton ATPase 116 kDa subunit a [KO:K02154]
122821834  atp6v0a1a; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
122822338  atp6v0ca; ATPase H+ transporting V0 subunit ca [KO:K02155]
122822734  atp6v0cb; ATPase H+ transporting V0 subunit cb [KO:K02155]
122841064  atp6v0b; V-type proton ATPase 21 kDa proteolipid subunit isoform X1 [KO:K03661]
122844960  atp6v0d1; V-type proton ATPase subunit d 1 [KO:K02146]
122830276  atpv0e2; ATPase H+ transporting V0 subunit e2 [KO:K02153]
122837542  atp6v0e1; V-type proton ATPase subunit e 1 [KO:K02153]
122830579  atp6ap1a; ATPase H+ transporting accessory protein 1a [KO:K03662]
122834979  V-type proton ATPase subunit S1-like isoform X1 [KO:K03662]
122843010  ppa1b; inorganic pyrophosphatase [KO:K01507] [EC:3.6.1.1]
122829019  ppa2; inorganic pyrophosphatase 2, mitochondrial isoform X1 [KO:K01507] [EC:3.6.1.1]
122822885  ppa1a; inorganic pyrophosphatase 2, mitochondrial [KO:K01507] [EC:3.6.1.1]
122823782  phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X1 [KO:K11725] [EC:3.6.1.1 3.1.3.-]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00080  H+
C00122  Fumarate
C00536  Triphosphate
Reference
PMID:16469879
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
PMID:16584177
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   
LinkDB

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