KEGG   PATHWAY: hsa03022
Entry
hsa03022                    Pathway                                
Name
Basal transcription factors - Homo sapiens (human)
Class
Genetic Information Processing; Transcription
Pathway map
hsa03022  Basal transcription factors
hsa03022

Other DBs
GO: 0005668 0005669 0005672 0005673 0005674 0005675
Organism
Homo sapiens (human) [GN:hsa]
Gene
1022  CDK7; cyclin-dependent kinase 7 isoform 1 [KO:K02202] [EC:2.7.11.22 2.7.11.23]
10629  TAF6L; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L [KO:K03131]
11036  GTF2A1L; TFIIA-alpha and beta-like factor isoform 1 [KO:K03122]
129685  TAF8; transcription initiation factor TFIID subunit 8 isoform 1 [KO:K14649]
138474  TAF1L; transcription initiation factor TFIID subunit 1-like [KO:K03125] [EC:2.3.1.48 2.7.11.1]
2068  ERCC2; general transcription and DNA repair factor IIH helicase subunit XPD isoform 1 [KO:K10844] [EC:5.6.2.3]
2071  ERCC3; general transcription and DNA repair factor IIH helicase/translocase subunit XPB isoform a [KO:K10843] [EC:5.6.2.4]
27097  TAF5L; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L isoform a [KO:K03130]
2957  GTF2A1; transcription initiation factor IIA subunit 1 isoform 1 [KO:K03122]
2958  GTF2A2; transcription initiation factor IIA subunit 2 [KO:K03123]
2959  GTF2B; transcription initiation factor IIB [KO:K03124]
2960  GTF2E1; general transcription factor IIE subunit 1 [KO:K03136]
2961  GTF2E2; transcription initiation factor IIE subunit beta isoform 1 [KO:K03137]
2962  GTF2F1; general transcription factor IIF subunit 1 [KO:K03138]
2963  GTF2F2; general transcription factor IIF subunit 2 [KO:K03139] [EC:5.6.2.-]
2965  GTF2H1; general transcription factor IIH subunit 1 [KO:K03141]
2966  GTF2H2; general transcription factor IIH subunit 2 isoform a [KO:K03142]
2967  GTF2H3; general transcription factor IIH subunit 3 isoform a [KO:K03143]
2968  GTF2H4; general transcription factor IIH subunit 4 [KO:K03144]
2969  GTF2I; general transcription factor II-I isoform 1 [KO:K03121]
387332  TBPL2; TATA box-binding protein-like 2 [KO:K03120]
404672  GTF2H5; general transcription factor IIH subunit 5 [KO:K10845]
4331  MNAT1; CDK-activating kinase assembly factor MAT1 isoform 1 [KO:K10842]
51616  TAF9B; transcription initiation factor TFIID subunit 9B [KO:K03133]
54457  TAF7L; transcription initiation factor TFIID subunit 7-like isoform 1 [KO:K03132]
6872  TAF1; transcription initiation factor TFIID subunit 1 isoform 3 [KO:K03125] [EC:2.3.1.48 2.7.11.1]
6873  TAF2; transcription initiation factor TFIID subunit 2 isoform 1 [KO:K03128]
6874  TAF4; transcription initiation factor TFIID subunit 4 [KO:K03129]
6875  TAF4B; transcription initiation factor TFIID subunit 4B isoform 2 [KO:K03129]
6877  TAF5; transcription initiation factor TFIID subunit 5 isoform 1 [KO:K03130]
6878  TAF6; transcription initiation factor TFIID subunit 6 isoform alpha [KO:K03131]
6879  TAF7; transcription initiation factor TFIID subunit 7 [KO:K03132]
6880  TAF9; transcription initiation factor TFIID subunit 9 [KO:K14535]
6881  TAF10; transcription initiation factor TFIID subunit 10 [KO:K03134]
6882  TAF11; transcription initiation factor TFIID subunit 11 isoform 1 [KO:K03135]
6883  TAF12; transcription initiation factor TFIID subunit 12 isoform 1 [KO:K03126]
6884  TAF13; transcription initiation factor TFIID subunit 13 [KO:K03127]
6908  TBP; TATA-box-binding protein isoform 1 [KO:K03120]
728340  GTF2H2C; general transcription factor IIH subunit 2-like protein isoform 1 [KO:K03142]
730394  GTF2H2C_2; general transcription factor IIH subunit 2-like protein isoform 1 [KO:K03142]
8148  TAF15; TATA-binding protein-associated factor 2N isoform 1 [KO:K14651]
83860  TAF3; transcription initiation factor TFIID subunit 3 [KO:K14650]
902  CCNH; cyclin-H isoform 1 [KO:K06634]
9519  TBPL1; TATA box-binding protein-like 1 [KO:K03120]
Reference
PMID:16858867
  Authors
Thomas MC, Chiang CM
  Title
The general transcription machinery and general cofactors.
  Journal
Crit Rev Biochem Mol Biol 41:105-78 (2006)
DOI:10.1080/10409230600648736
Reference
PMID:12516863
  Authors
Martinez E
  Title
Multi-protein complexes in eukaryotic gene transcription.
  Journal
Plant Mol Biol 50:925-47 (2002)
DOI:10.1023/A:1021258713850
Reference
PMID:19308322
  Authors
Cler E, Papai G, Schultz P, Davidson I
  Title
Recent advances in understanding the structure and function of general transcription factor TFIID.
  Journal
Cell Mol Life Sci 66:2123-34 (2009)
DOI:10.1007/s00018-009-0009-3
Reference
PMID:10838567
  Authors
Malik S, Roeder RG.
  Title
Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells.
  Journal
Trends Biochem Sci 25:277-283 (2000)
DOI:10.1016/S0968-0004(00)01596-6
Related
pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
KO pathway
ko03022   

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