KEGG T01001: 1030

Homo sapiens (human): 1030

Entry

1030              CDS       T01001

Symbol

CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b

Name

(RefSeq) cyclin dependent kinase inhibitor 2B

K04685

cyclin-dependent kinase inhibitor 2B

Organism

hsa Homo sapiens (human)

Pathway

hsa04068

FoxO signaling pathway

hsa04110

Cell cycle

hsa04218

Cellular senescence

hsa04350

TGF-beta signaling pathway

hsa04934

Cushing syndrome

hsa05166

Human T-cell leukemia virus 1 infection

hsa05200

Pathways in cancer

hsa05203

Viral carcinogenesis

hsa05222

Small cell lung cancer

hsa05226

Gastric cancer

Network

nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06230  Cell cycle (cancer)
nt06267  Small cell lung cancer

Element

N00088

Amplified MYC to p15-cell cycle G1/S

N00090

p15-Cell cycle G1/S

N00495

HTLV-1 Tax to p15-cell cycle G1/S

Disease

H00015

Malignant pleural mesothelioma

H00036

Osteosarcoma

H01463

Mycosis fungoides

H01556

Meningioma

H02434

Diffuse large B-cell lymphoma, not otherwise specified

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    1030 (CDKN2B)
   04068 FoxO signaling pathway
    1030 (CDKN2B)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    1030 (CDKN2B)
   04218 Cellular senescence
    1030 (CDKN2B)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1030 (CDKN2B)
   05203 Viral carcinogenesis
    1030 (CDKN2B)
  09162 Cancer: specific types
   05226 Gastric cancer
    1030 (CDKN2B)
   05222 Small cell lung cancer
    1030 (CDKN2B)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    1030 (CDKN2B)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    1030 (CDKN2B)

SSDB

Motif

Pfam:

Ank_2 Ank Ank_4 Ank_5

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

LinkDB

Position

9:complement(22002903..22009313)

AA seq 138 aa
MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSAR
VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA
EERGHRDVAGYLRTATGD

NT seq 417 nt +upstreamnt +downstreamnt
atgcgcgaggagaacaagggcatgcccagtgggggcggcagcgatgagggtctggccagc
gccgcggcgcggggactagtggagaaggtgcgacagctcctggaagccggcgcggatccc
aacggagtcaaccgtttcgggaggcgcgcgatccaggtcatgatgatgggcagcgcccgc
gtggcggagctgctgctgctccacggcgcggagcccaactgcgcagaccctgccactctc
acccgaccggtgcatgatgctgcccgggagggcttcctggacacgctggtggtgctgcac
cgggccggggcgcggctggacgtgcgcgatgcctggggtcgtctgcccgtggacttggcc
gaggagcggggccaccgcgacgttgcagggtacctgcgcacagccacgggggactga

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