KEGG   Homo sapiens (human): 1063
Entry
1063              CDS       T01001                                 
Symbol
CENPF, CENF, CILD31, PRO1779, STROMS, hcp-1
Name
(RefSeq) centromere protein F
  KO
K11499  centromere protein F
Organism
hsa  Homo sapiens (human)
Network
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N01534  Dynein recruitment to the kinetochore
N01535  Kinetochore microtubule attachment
Disease
H01814  Stromme syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    1063 (CENPF)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Kinetochore proteins
    Centromere proteins
     1063 (CENPF)
SSDB
Motif
Pfam: CENP-F_N CENP-F_leu_zip CENP-F_C_Rb_bdg CCDC39 PGM_PMM_IV
Other DBs
NCBI-GeneID: 1063
NCBI-ProteinID: NP_057427
OMIM: 600236
HGNC: 1857
Ensembl: ENSG00000117724
UniProt: P49454
LinkDB
Position
1:214603195..214664571
AA seq 3114 aa
MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKT
EGTNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKR
CKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKR
LEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRD
FSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELR
LQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTAL
EQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR
LTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRS
MEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDL
QEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLS
ALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHE
YNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIEN
MCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDH
QRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLE
SQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVA
ETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSS
IISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQ
EKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAK
EHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQN
KMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKE
ISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISG
LKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTE
LNDSRSECITATRKMAEEVGKLLNEVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVS
LAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVD
SLKAENLVLSTNLRNFQGDLVKEMQLGLEEGLVPSLSSSCVPDSSSLSSLGDSSFYRALL
EQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKGVEELESLCEVYR
QSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEM
ESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSE
TTERTPKHDVHQICDKDAQQDLNLDIEKITETGAVKPTGECSGEQSPDTNYEPPGEDKTQ
GSSECISELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESL
LNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV
ETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALY
LEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQL
SEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSL
EKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEK
GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLE
RELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQ
EKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQE
IMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVEN
LERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNE
LQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHND
QEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKK
DEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQ
DTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELS
GEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQ
LRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSL
KATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQ
AAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEM
LETQVAHLCSQQSKQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASGKRQRSSGIWE
NGRGPTPATPESFSKKSKKAVMSGIHPAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPY
ILRRTTMATRTSPRLAAQKLALSPLSLGKENLAESSKPTAGGSRSQKVKVAQRSPVDSGT
ILREPTTKSVPVNNLPERSPTDSPREGLRVKRGRLVPSPKAGLESNGSENCKVQ
NT seq 9345 nt   +upstreamnt  +downstreamnt
atgagctgggctttggaagaatggaaagaagggctgcctacaagagctcttcagaaaatt
caagagcttgaaggacagcttgacaaactgaagaaggaaaagcagcaaaggcagtttcag
cttgacagtctcgaggctgcgctgcagaagcaaaaacagaaggttgaaaatgaaaaaacc
gagggtacaaacctgaaaagggagaatcaaagattgatggaaatatgtgaaagtctggag
aaaactaagcagaagatttctcatgaacttcaagtcaaggagtcacaagtgaatttccag
gaaggacaactgaattcaggcaaaaaacaaatagaaaaactggaacaggaacttaaaagg
tgtaaatctgagcttgaaagaagccaacaagctgcgcagtctgcagatgtctctctgaat
ccatgcaatacaccacaaaaaatttttacaactccactaacaccaagtcaatattatagt
ggttccaagtatgaagatctaaaagaaaaatataataaagaggttgaagaacgaaaaaga
ttagaggcagaggttaaagccttgcaggctaaaaaagcaagccagactcttccacaagcc
accatgaatcaccgcgacattgcccggcatcaggcttcatcatctgtgttctcatggcag
caagagaagaccccaagtcatctttcatctaattctcaaagaactccaattaggagagat
ttctctgcatcttacttttctggggaacaagaggtgactccaagtcgatcaactttgcaa
atagggaaaagagatgctaatagcagtttctttgacaattctagcagtcctcatcttttg
gatcaattaaaagcgcagaatcaagagctaagaaacaagattaatgagttggaactacgc
ctgcaaggacatgaaaaagaaatgaaaggccaagtgaataagtttcaagaactccaactc
caactggagaaagcaaaagtggaattaattgaaaaagagaaagttttgaacaaatgtagg
gatgaactagtgagaacaacagcacaatacgaccaggcgtcaaccaagtatactgcattg
gaacaaaaactgaaaaaattgacggaagatttgagttgtcagcgacaaaatgcagaaagt
gccagatgttctctggaacagaaaattaaggaaaaagaaaaggagtttcaagaggagctc
tcccgtcaacagcgttctttccaaacactggaccaggagtgcatccagatgaaggccaga
ctcacccaggagttacagcaagccaagaatatgcacaacgtcctgcaggctgaactggat
aaactcacatcagtaaagcaacagctagaaaacaatttggaagagtttaagcaaaagttg
tgcagagctgaacaggcgttccaggcgagtcagatcaaggagaatgagctgaggagaagc
atggaggaaatgaagaaggaaaacaacctccttaagagtcactctgagcaaaaggccaga
gaagtctgccacctggaggcagaactcaagaacatcaaacagtgtttaaatcagagccag
aattttgcagaagaaatgaaagcgaagaatacctctcaggaaaccatgttaagagatctt
caagaaaaaataaatcagcaagaaaactccttgactttagaaaaactgaagcttgctgtg
gctgatctggaaaagcagcgagattgttctcaagaccttttgaagaaaagagaacatcac
attgaacaacttaatgataagttaagcaagacagagaaagagtccaaagccttgctgagt
gctttagagttaaaaaagaaagaatatgaagaattgaaagaagagaaaactctgttttct
tgttggaaaagtgaaaacgaaaaacttttaactcagatggaatcagaaaaggaaaacttg
cagagtaaaattaatcacttggaaacttgtctgaagacacagcaaataaaaagtcatgaa
tacaacgagagagtaagaacgctggagatggacagagaaaacctaagtgtcgagatcaga
aaccttcacaacgtgttagacagtaagtcagtggaggtagagacccagaaactagcttat
atggagctacagcagaaagctgagttctcagatcagaaacatcagaaggaaatagaaaat
atgtgtttgaagacttctcagcttactgggcaagttgaagatctagaacacaagcttcag
ttactgtcaaatgaaataatggacaaagaccggtgttaccaagacttgcatgccgaatat
gagagcctcagggatctgctaaaatccaaagatgcttctctggtgacaaatgaagatcat
cagagaagtcttttggcttttgatcagcagcctgccatgcatcattcctttgcaaatata
attggagaacaaggaagcatgccttcagagaggagtgaatgtcgtttagaagcagaccaa
agtccgaaaaattctgccatcctacaaaatagagttgattcacttgaattttcattagag
tctcaaaaacagatgaactcagacctgcaaaagcagtgtgaagagttggtgcaaatcaaa
ggagaaatagaagaaaatctcatgaaagcagaacagatgcatcaaagttttgtggctgaa
acaagtcagcgcattagtaagttacaggaagacacttctgctcaccagaatgttgttgct
gaaaccttaagtgcccttgagaacaaggaaaaagagctgcaacttttaaatgataaggta
gaaactgagcaggcagagattcaagaattaaaaaagagcaaccatctacttgaagactct
ctaaaggagctacaacttttatccgaaaccctaagcttggagaagaaagaaatgagttcc
atcatttctctaaataaaagggaaattgaagagctgacccaagagaatgggactcttaag
gaaattaatgcatccttaaatcaagagaagatgaacttaatccagaaaagtgagagtttt
gcaaactatatagatgaaagggagaaaagcatttcagagttatctgatcagtacaagcaa
gaaaaacttattttactacaaagatgtgaagaaaccggaaatgcatatgaggatcttagt
caaaaatacaaagcagcacaggaaaagaattctaaattagaatgcttgctaaatgaatgc
actagtctttgtgaaaataggaaaaatgagttggaacagctaaaggaagcatttgcaaag
gaacaccaagaattcttaacaaaattagcatttgctgaagaaagaaatcagaatctgatg
ctagagttggagacagtgcagcaagctctgagatctgagatgacagataaccaaaacaat
tctaagagcgaggctggtggtttaaagcaagaaatcatgactttaaaggaagaacaaaac
aaaatgcaaaaggaagttaatgacttattacaagagaatgaacagctgatgaaggtaatg
aagactaaacatgaatgtcaaaatctagaatcagaaccaattaggaactctgtgaaagaa
agagagagtgagagaaatcaatgtaattttaaacctcagatggatcttgaagttaaagaa
atttctctagatagttataatgcgcagttggtgcaattagaagctatgctaagaaataag
gaattaaaacttcaggaaagtgagaaggagaaggagtgcctgcagcatgaattacagaca
attagaggagatcttgaaaccagcaatttgcaagacatgcagtcacaagaaattagtggc
cttaaagactgtgaaatagatgcggaagaaaagtatatttcagggcctcatgagttgtca
acaagtcaaaacgacaatgcacaccttcagtgctctctgcaaacaacaatgaacaagctg
aatgagctagagaaaatatgtgaaatactgcaggctgaaaagtatgaactcgtaactgag
ctgaatgattcaaggtcagaatgtatcacagcaactaggaaaatggcagaagaggtaggg
aaactactaaatgaagttaaaatattaaatgatgacagtggtcttctccatggtgagtta
gtggaagacataccaggaggtgaatttggtgaacaaccaaatgaacagcaccctgtgtct
ttggctccattggacgagagtaattcctacgagcacttgacattgtcagacaaagaagtt
caaatgcactttgccgaattgcaagagaaattcttatctttacaaagtgaacacaaaatt
ttacatgatcagcactgtcagatgagctctaaaatgtcagagctgcagacctatgttgac
tcattaaaggccgaaaatttggtcttgtcaacgaatctgagaaactttcaaggtgacttg
gtgaaggagatgcagctgggcttggaggaggggctcgttccatccctgtcatcctcttgt
gtgcctgacagctctagtcttagcagtttgggagactcctccttttacagagctctttta
gaacagacaggagatatgtctcttttgagtaatttagaaggggctgtttcagcaaaccag
tgcagtgtagatgaagtattttgcagcagtctgcaggaggagaatctgaccaggaaagaa
accccttcggccccagcgaagggtgttgaagagcttgagtccctctgtgaggtgtaccgg
cagtccctcgagaagctagaagagaaaatggaaagtcaagggattatgaaaaataaggaa
attcaagagctcgagcagttattaagttctgaaaggcaagagcttgactgccttaggaag
cagtatttgtcagaaaatgaacagtggcaacagaagctgacaagcgtgactctggagatg
gagtccaagttggcggcagaaaagaaacagacggaacaactgtcacttgagctggaagta
gcacgactccagctacaaggtctggacttaagttctcggtctttgcttggcatcgacaca
gaagatgctattcaaggccgaaatgagagctgtgacatatcaaaagaacatacttcagaa
actacagaaagaacaccaaagcatgatgttcatcagatttgtgataaagatgctcagcag
gacctcaatctagacattgagaaaataactgagactggtgcagtgaaacccacaggagag
tgctctggggaacagtccccagataccaattatgagcctccaggggaagataaaacccag
ggctcttcagaatgcatttctgaattgtcattttctggtcctaatgctttggtacctatg
gatttcctggggaatcaggaagatatccataatcttcaactgcgggtaaaagagacatca
aatgagaatttgagattacttcatgtgatagaggaccgtgacagaaaagttgaaagtttg
ctaaatgaaatgaaagaattagactcaaaactccatttacaggaggtacaactaatgacc
aaaattgaagcatgcatagaattggaaaaaatagttggggaacttaagaaagaaaactca
gatttaagtgaaaaattggaatatttttcttgtgatcaccaggagttactccagagagta
gaaacttctgaaggcctcaattctgatttagaaatgcatgcagataaatcatcacgtgaa
gatattggagataatgtggccaaggtgaatgacagctggaaggagagatttcttgatgtg
gaaaatgagctgagtaggatcagatcggagaaagctagcattgagcatgaagccctctac
ctggaggctgacttagaggtagttcaaacagagaagctatgtttagaaaaagacaatgaa
aataagcagaaggttattgtctgccttgaagaagaactctcagtggtcacaagtgagaga
aaccagcttcgtggagaattagatactatgtcaaaaaaaaccacggcactggatcagttg
tctgaaaaaatgaaggagaaaacacaagagcttgagtctcatcaaagtgagtgtctccat
tgcattcaggtggcagaggcagaggtgaaggaaaagacggaactccttcagactttgtcc
tctgatgtgagtgagctgttaaaagacaaaactcatctccaggaaaagctgcagagtttg
gaaaaggactcacaggcactgtctttgacaaaatgtgagctggaaaaccaaattgcacaa
ctgaataaagagaaagaattgcttgtcaaggaatctgaaagcctgcaggccagactgagt
gaatcagattatgaaaagctgaatgtctccaaggccttggaggccgcactggtggagaaa
ggtgagttcgcattgaggctgagctcaacacaggaggaagtgcatcagctgagaagaggc
atcgagaaactgagagttcgcattgaggccgatgaaaagaagcagctgcacatcgcagag
aaactgaaagaacgcgagcgggagaatgattcacttaaggataaagttgagaaccttgaa
agggaattgcagatgtcagaagaaaaccaggagctagtgattcttgatgccgagaattcc
aaagcagaagtagagactctaaaaacacaaatagaagagatggccagaagcctgaaagtt
tttgaattagaccttgtcacgttaaggtctgaaaaagaaaatctgacaaaacaaatacaa
gaaaaacaaggtcagttgtcagaactagacaagttactctcttcatttaaaagtctgtta
gaagaaaaggagcaagcagagatacagatcaaagaagaatctaaaactgcagtggagatg
cttcagaatcagttaaaggagctaaatgaggcagtagcagccttgtgtggtgaccaagaa
attatgaaggccacagaacagagtctagacccaccaatagaggaagagcatcagctgaga
aatagcattgaaaagctgagagcccgcctagaagctgatgaaaagaagcagctctgtgtc
ttacaacaactgaaggaaagtgagcatcatgcagatttacttaagggtagagtggagaac
cttgaaagagagctagagatagccaggacaaaccaagagcatgcagctcttgaggcagag
aattccaaaggagaggtagagaccctaaaagcaaaaatagaagggatgacccaaagtctg
agaggtctggaattagatgttgttactataaggtcagaaaaagaaaatctgacaaatgaa
ttacaaaaagagcaagagcgaatatctgaattagaaataataaattcatcatttgaaaat
attttgcaagaaaaagagcaagagaaagtacagatgaaagaaaaatcaagcactgccatg
gagatgcttcaaacacaattaaaagagctcaatgagagagtggcagccctgcataatgac
caagaagcctgtaaggccaaagagcagaatcttagtagtcaagtagagtgtcttgaactt
gagaaggctcagttgctacaaggccttgatgaggccaaaaataattatattgttttgcaa
tcttcagtgaatggcctcattcaagaagtagaagatggcaagcagaaactggagaagaag
gatgaagaaatcagtagactgaaaaatcaaattcaagaccaagagcagcttgtctctaaa
ctgtcccaggtggaaggagagcaccaactttggaaggagcaaaacttagaactgagaaat
ctgacagtggaattggagcagaagatccaagtgctacaatccaaaaatgcctctttgcag
gacacattagaagtgctgcagagttcttacaagaatctagagaatgagcttgaattgaca
aaaatggacaaaatgtcctttgttgaaaaagtaaacaaaatgactgcaaaggaaactgag
ctgcagagggaaatgcatgagatggcacagaaaacagcagagctgcaagaagaactcagt
ggagagaaaaataggctagctggagagttgcagttactgttggaagaaataaagagcagc
aaagatcaattgaaggagctcacactagaaaatagtgaattgaagaagagcctagattgc
atgcacaaagaccaggtggaaaaggaagggaaagtgagagaggaaatagctgaatatcag
ctacggcttcatgaagctgaaaagaaacaccaggctttgcttttggacacaaacaaacag
tatgaagtagaaatccagacataccgagagaaattgacttctaaagaagaatgtctcagt
tcacagaagctggagatagaccttttaaagtctagtaaagaagagctcaataattcattg
aaagctactactcagattttggaagaattgaagaaaaccaagatggacaatctaaaatat
gtaaatcagttgaagaaggaaaatgaacgtgcccaggggaaaatgaagttgttgatcaaa
tcctgtaaacagctggaagaggaaaaggagatactgcagaaagaactctctcaacttcaa
gctgcacaggagaagcagaaaacaggtactgttatggataccaaggtcgatgaattaaca
actgagatcaaagaactgaaagaaactcttgaagaaaaaaccaaggaggcagatgaatac
ttggataagtactgttccttgcttataagccatgaaaagttagagaaagctaaagagatg
ttagagacacaagtggcccatctgtgttcacagcaatctaaacaagattcccgagggtct
cctttgctaggtccagttgttccaggaccatctccaatcccttctgttactgaaaagagg
ttatcatctggccaaaataaagcttcaggcaagaggcaaagatccagtggaatatgggag
aatggtagaggaccaacacctgctaccccagagagcttttctaaaaaaagcaagaaagca
gtcatgagtggtattcaccctgcagaagacacggaaggtactgagtttgagccagaggga
cttccagaagttgtaaagaaagggtttgctgacatcccgacaggaaagactagcccatat
atcctgcgaagaacaaccatggcaactcggaccagcccccgcctggctgcacagaagtta
gcgctatccccactgagtctcggcaaagaaaatcttgcagagtcctccaaaccaacagct
ggtggcagcagatcacaaaaggtcaaagttgctcagcggagcccagtagattcaggcacc
atcctccgagaacccaccacgaaatccgtcccagtcaataatcttcctgagagaagtccg
actgacagccccagagagggcctgagggtcaagcgaggccgacttgtccccagccccaaa
gctggactggagtccaacggcagtgagaactgtaaggtccagtga

KEGG   Homo sapiens (human): 701
Entry
701               CDS       T01001                                 
Symbol
BUB1B, BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Name
(RefSeq) BUB1 mitotic checkpoint serine/threonine kinase B
  KO
K06637  mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa05166  Human T-cell leukemia virus 1 infection
Network
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06230  Cell cycle (cancer)
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N00493  Spindle assembly checkpoint signaling
N01529  Recruitment and formation of the MCC
N01533  Disassembly of MCC
N01535  Kinetochore microtubule attachment
Disease
H00020  Colorectal cancer
H01288  Mosaic variegated aneuploidy syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    701 (BUB1B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    701 (BUB1B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    701 (BUB1B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    701 (BUB1B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     701 (BUB1B)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  BUB family
   701 (BUB1B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     701 (BUB1B)
SSDB
Motif
Pfam: Mad3_BUB1_I Pkinase Mad3_BUB1_II PK_Tyr_Ser-Thr
Other DBs
NCBI-GeneID: 701
NCBI-ProteinID: NP_001202
OMIM: 602860
HGNC: 1149
Ensembl: ENSG00000156970
UniProt: O60566
Structure
LinkDB
Position
15:40161069..40221123
AA seq 1050 aa
MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKR
AFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPR
FLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQ
QKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARA
PIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPM
PRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETARQPVMTPCKIEP
SINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVF
RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKL
QIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKK
NKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVT
ICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIY
SQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQS
PWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKL
FWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYIN
CFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDC
NKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLA
HLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMN
GVFDTTFQSHLNKALWKVGKLTSPGALLFQ
NT seq 3153 nt   +upstreamnt  +downstreamnt
atggcggcggtgaagaaggaagggggtgctctgagtgaagccatgtccctggagggagat
gaatgggaactgagtaaagaaaatgtacaacctttaaggcaagggcggatcatgtccacg
cttcagggagcactggcacaagaatctgcctgtaacaatactcttcagcagcagaaacgg
gcatttgaatatgaaattcgattttacactggaaatgaccctctggatgtttgggatagg
tatatcagctggacagagcagaactatcctcaaggtgggaaggagagtaatatgtcaacg
ttattagaaagagctgtagaagcactacaaggagaaaaacgatattatagtgatcctcga
tttctcaatctctggcttaaattagggcgtttatgcaatgagcctttggatatgtacagt
tacttgcacaaccaagggattggtgtttcacttgctcagttctatatctcatgggcagaa
gaatatgaagctagagaaaactttaggaaagcagatgcgatatttcaggaagggattcaa
cagaaggctgaaccactagaaagactacagtcccagcaccgacaattccaagctcgagtg
tctcggcaaactctgttggcacttgagaaagaagaagaggaggaagtttttgagtcttct
gtaccacaacgaagcacactagctgaactaaagagcaaagggaaaaagacagcaagagct
ccaatcatccgtgtaggaggtgctctcaaggctccaagccagaacagaggactccaaaat
ccatttcctcaacagatgcaaaataatagtagaattactgtttttgatgaaaatgctgat
gaggcttctacagcagagttgtctaagcctacagtccagccatggatagcaccccccatg
cccagggccaaagagaatgagctgcaagcaggcccttggaacacaggcaggtccttggaa
cacaggcctcgtggcaatacagcttcactgatagctgtacccgctgtgcttcccagtttc
actccatatgtggaagagactgcacgacagccagttatgacaccatgtaaaattgaacct
agtataaaccacatcctaagcaccagaaagcctggaaaggaagaaggagatcctctacaa
agggttcagagccatcagcaagcgtctgaggagaagaaagagaagatgatgtattgtaag
gagaagatttatgcaggagtaggggaattctcctttgaagaaattcgggctgaagttttc
cggaagaaattaaaagagcaaagggaagccgagctattgaccagtgcagagaagagagca
gaaatgcagaaacagattgaagagatggagaagaagctaaaagaaatccaaactactcag
caagaaagaacaggtgatcagcaagaagagacgatgcctacaaaggagacaactaaactg
caaattgcttccgagtctcagaaaataccaggaatgactctatccagttctgtttgtcaa
gtaaactgttgtgccagagaaacttcacttgcggagaacatttggcaggaacaacctcat
tctaaaggtcccagtgtacctttctccatttttgatgagtttcttctttcagaaaagaag
aataaaagtcctcctgcagatcccccacgagttttagctcaacgaagaccccttgcagtt
ctcaaaacctcagaaagcatcacctcaaatgaagatgtgtctccagatgtttgtgatgaa
tttacaggaattgaacccttgagcgaggatgccattatcacaggcttcagaaatgtaaca
atttgtcctaacccagaagacacttgtgactttgccagagcagctcgttttgtatccact
ccttttcatgagataatgtccttgaaggatctcccttctgatcctgagagactgttaccg
gaagaagatctagatgtaaagacctctgaggaccagcagacagcttgtggcactatctac
agtcagactctcagcatcaagaagctgagcccaattattgaagacagtcgtgaagccaca
cactcctctggcttctctggttcttctgcctcggttgcaagcacctcctccatcaaatgt
cttcaaattcctgagaaactagaacttactaatgagacttcagaaaaccctactcagtca
ccatggtgttcacagtatcgcagacagctactgaagtccctaccagagttaagtgcctct
gcagagttgtgtatagaagacagaccaatgcctaagttggaaattgagaaggaaattgaa
ttaggtaatgaggattactgcattaaacgagaatacctaatatgtgaagattacaagtta
ttctgggtggcgccaagaaactctgcagaattaacagtaataaaggtatcttctcaacct
gtcccatgggacttttatatcaacctcaagttaaaggaacgtttaaatgaagattttgat
catttttgcagctgttatcaatatcaagatggctgtattgtttggcaccaatatataaac
tgcttcacccttcaggatcttctccaacacagtgaatatattacccatgaaataacagtg
ttgattatttataaccttttgacaatagtggagatgctacacaaagcagaaatagtccat
ggtgacttgagtccaaggtgtctgattctcagaaacagaatccacgatccctatgattgt
aacaagaacaatcaagctttgaagatagtggacttttcctacagtgttgaccttagggtg
cagctggatgtttttaccctcagcggctttcggactgtacagatcctggaaggacaaaag
atcctggctaactgttcttctccctaccaggtagacctgtttggtatagcagatttagca
catttactattgttcaaggaacacctacaggtcttctgggatgggtccttctggaaactt
agccaaaatatttctgagctaaaagatggtgaattgtggaataaattctttgtgcggatt
ctgaatgccaatgatgaggccacagtgtctgttcttggggagcttgcagcagaaatgaat
ggggtttttgacactacattccaaagtcacctgaacaaagccttatggaaggtagggaag
ttaactagtcctggggctttgctctttcagtga

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