Homo sapiens (human): 10718
Help
Entry
10718 CDS
T01001
Symbol
NRG3, HRG3, pro-NRG3
Name
(RefSeq) neuregulin 3
KO
K05457
neuregulin 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa05014
Amyotrophic lateral sclerosis
Network
nt06464
Amyotrophic lateral sclerosis
nt06530
PI3K signaling
nt06543
NRG-ERBB signaling
Element
N01163
NRG-ERBB4-PI3K signaling pathway
N01164
Mutation-inactivated ERBB4 to NRG-ERBB4-PI3K signaling pathway
N01656
GF-RTK-PI3K signaling pathway
N01658
GF-RTK-RAS-PI3K signaling pathway
N01877
ERBB4 mutation to GF-RTK-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
10718 (NRG3)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
10718 (NRG3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
10718 (NRG3)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Growth factors (RTK binding)
10718 (NRG3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EGF
JAG1-like_EGF2
LapA_dom
DUF6479
DUF6612
EGF_laminin
EGF_Teneurin
EGF_DL_JAG
Motif
Other DBs
NCBI-GeneID:
10718
NCBI-ProteinID:
NP_001357013
OMIM:
605533
HGNC:
7999
Ensembl:
ENSG00000185737
UniProt:
P56975
D9ZHP6
LinkDB
All DBs
Position
10:81875194..82987179
Genome browser
AA seq
720 aa
AA seq
DB search
MSEGAAAASPPGAASAAAASAEEGTAAAAAAAAAGGGPDGGGEGAAEPPRELRCSDCIVW
NRQQTWLCVVPLFIGFIGLGLSLMLLKWIVVGSVKEYVPTDLVDSKGMGQDPFFLSKPSS
FPKAMETTTTTTSTTSPATPSAGGAASSRTPNRISTRLTTITRAPTRFPGHRVPIRASPR
STTARNTAAPATVPSTTAPFFSSSTLGSRPPVPGTPSTQAMPSWPTAAYATSSYLHDSTP
SWTLSPFQDAASSSSSSSSSATTTTPETSTSPKFHTTTYSTERSEHFKPCRDKDLAYCLN
DGECFVIETLTGSHKHCRCKEGYQGVRCDQFLPKTDSILSDPTDHLGIEFMESEEVYQRQ
VLSISCIIFGIVIVGMFCAAFYFKSKKQAKQIQEQLKVPQNGKSYSLKASSTMAKSENLV
KSHVQLQNYSKVERHPVTALEKMMESSFVGPQSFPEVPSPDRGSQSVKHHRSLSSCCSPG
QRSGMLHRNAFRRTPPSPRSRLGGIVGPAYQQLEESRIPDQDTIPCQGIEVRKTISHLPI
QLWCVERPLDLKYSSSGLKTQRNTSINMQLPSRETNPYFNSLEQKDLVGYSSTRASSVPI
IPSVGLEETCLQMPGISEVKSIKWCKNSYSADVVNVSIPVSDCLIAEQQEVKILLETVQE
QIRILTDARRSEDYELASVETEDSASENTAFLPLSPTAKSEREAQFVLRNEIQRDSALTK
NT seq
2163 nt
NT seq
+upstream
nt +downstream
nt
atgagtgaaggggcggccgctgcctcgccacctggtgccgcttcggcagccgccgcctcg
gccgaggagggcaccgcggcggctgcggcggcggcagcggcgggcgggggcccggacggc
ggcggcgaaggggcggccgagcccccccgggagttacgctgtagcgactgcatcgtgtgg
aaccggcagcagacgtggctgtgcgtggtacctctgttcatcggcttcatcggcctgggg
ctcagcctcatgcttctcaaatggatcgtggtgggctccgtcaaggagtacgtgcccacc
gacctagtggactccaaggggatgggccaggaccccttcttcctctccaagcccagctct
ttccccaaggccatggagaccaccaccactaccacttccaccacgtcccccgccaccccc
tccgccgggggtgccgcctcctccaggacgcccaaccggattagcactcgcctgaccacc
atcacgcgggcgcccactcgcttccccgggcaccgggtgcccatccgggccagcccgcgc
tccaccacagcacggaacactgcggcccctgcgacggtcccgtccaccacggccccgttc
ttcagtagcagcacgctgggctcccgacccccggtgccaggaactccaagtacccaggca
atgccctcctggcctactgcggcatacgctacctcctcctaccttcacgattctactccc
tcctggaccctgtctccctttcaggatgctgcctcctcttcttcctcttcttcctcctcc
gctaccaccaccacaccagaaactagcaccagccccaaatttcatacgacgacatattcc
acagagcgatccgagcacttcaaaccctgccgagacaaggaccttgcatactgtctcaat
gatggcgagtgctttgtgatcgaaaccctgaccggatcccataaacactgtcggtgcaaa
gaaggctaccaaggagtccgttgtgatcaatttctgccgaaaactgattccatcttatcg
gatccaacagaccacttggggattgaattcatggagagtgaagaagtttatcaaaggcag
gtgctgtcaatttcatgtatcatctttggaattgtcatcgtgggcatgttctgtgcagca
ttctacttcaaaagcaagaaacaagctaaacaaatccaagagcagctgaaagtgccacaa
aatggtaaaagctacagtctcaaagcatccagcacaatggcaaagtcagagaacttggtg
aagagccatgtccagctgcaaaattattcaaaggtggaaaggcatcctgtgactgcattg
gagaaaatgatggagtcaagttttgtcggcccccagtcattccctgaggtcccttctcct
gacagaggaagccagtctgtcaaacaccacaggagtctatcctcttgctgcagcccaggg
caaagaagtggcatgctccataggaatgccttcagaaggacacccccgtcaccccgaagt
aggctaggtggaattgtgggaccagcatatcagcaactcgaagaatcaaggatcccagac
caggatacgataccttgccaagggatagaggtcaggaagactatatcccacctgcctata
cagctgtggtgtgttgaaagacccctggacttaaagtattcatccagtggtttaaaaacc
caacgaaatacatcaataaatatgcaactgccttcaagagagacaaacccctattttaat
agcttggagcaaaaggacctggtgggctattcatccacaagggccagttctgtgcccatc
atcccttcagtgggtttagaggaaacctgcctgcaaatgccagggatttctgaagtcaaa
agcatcaaatggtgcaaaaactcctattcagctgacgttgtcaatgtgagtattccagtc
agcgattgtcttatagcagaacaacaagaagtgaaaatattgctagaaactgtccaggag
cagatccgaattctgactgatgccagacggtcagaagactacgaactggccagcgtagaa
accgaggacagtgcaagcgaaaacacagcctttctccccctgagtcccacagccaaatca
gaacgagaggcgcaatttgtcttaagaaatgaaatacaaagagactctgcattgaccaag
tga
DBGET
integrated database retrieval system
