Homo sapiens (human): 3360 Help Entry 3360              CDS       T01001                                  Symbol HTR4, 5-HT4, 5-HT4R Name (RefSeq) 5-hydroxytryptamine receptor 4   KO K04160   5-hydroxytryptamine receptor 4 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse Drug target Cinitapride (DG01520):  D07700 D07701 Cisapride (DG00056):  D00274 D02092 Fabesetron hydrochloride:  D01838 Felcisetrag:  D12157 Mosapride (DG01285):  D01994<JP> D08236 Naronapride (DG01335):  D09933 D09934 Piboserod hydrochloride:  D05471 Prucalopride (DG00080):  D09205 D10152<US> Relenopride (DG02948):  D11220 D11221 Renzapride:  D06396 Sulamserod hydrochloride:  D05941 Tegaserod (DG00081):  D02730 D06056 Velusetrag (DG01336):  D09693 D09694 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3360 (HTR4)    04024 cAMP signaling pathway     3360 (HTR4)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3360 (HTR4)    04082 Neuroactive ligand signaling     3360 (HTR4)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3360 (HTR4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3360 (HTR4) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3360 (HTR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 DUF6249 zf-LITAF-like DUF7471 Motif Other DBs NCBI-GeneID:  3360 NCBI-ProteinID:  NP_000861 OMIM:  602164 HGNC:  5299 Ensembl:  ENSG00000164270 UniProt:  Q13639 A0A2D3FAF9 Structure PDBPDBj LinkDB All DBs Position 5:complement(148451032..148654527) Genome browser AA seq 388 aa AA seqDB search MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD AVECGGQWESQCHPPATSPLVAAQPSDT NT seq 1167 nt NT seq  +upstreamnt  +downstreamnt atggacaaacttgatgctaatgtgagttctgaggagggtttcgggtcagtggagaaggtg gtgctgctcacgtttctctcgacggttatcctgatggccatcttggggaacctgctggtg atggtggctgtgtgctgggacaggcagctcaggaaaataaaaacaaattatttcattgta tctcttgcttttgcggatctgctggtttcggtgctggtgatgccctttggtgccattgag ctggttcaagacatctggatttatggggaggtgttttgtcttgttcggacatctctggac gtcctgctcacaacggcatcgatttttcacctgtgctgcatttctctggataggtattac gccatctgctgccagcctttggtctataggaacaagatgacccctctgcgcatcgcatta atgctgggaggctgctgggtcatccccacgtttatttcttttctccctataatgcaaggc tggaataacattggcataattgatttgatagaaaagaggaagttcaaccagaactctaac tctacgtactgtgtcttcatggtcaacaagccctacgccatcacctgctctgtggtggcc ttctacatcccatttctcctcatggtgctggcctattaccgcatctatgtcacagctaag gagcatgcccatcagatccagatgttacaacgggcaggagcctcctccgagagcaggcct cagtcggcagaccagcatagcactcatcgcatgaggacagagaccaaagcagccaagacc ctgtgcatcatcatgggttgcttctgcctctgctgggcaccattctttgtcaccaatatt gtggatcctttcatagactacactgtccctgggcaggtgtggactgctttcctctggctc ggctatatcaattccgggttgaacccttttctctacgccttcttgaataagtcttttaga cgtgccttcctcatcatcctctgctgtgatgatgagcgctaccgaagaccttccattctg ggccagactgtcccttgttcaaccacaaccattaatggatccacacatgtactaagggat gcagtggagtgtggtggccagtgggagagtcagtgtcacccgccagcaacttctcctttg gtggctgctcagcccagtgacacttag

Homo sapiens (human): 3362 Help Entry 3362              CDS       T01001                                  Symbol HTR6, 5-HT6, 5-HT6R Name (RefSeq) 5-hydroxytryptamine receptor 6   KO K04162   5-hydroxytryptamine receptor 6 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse Drug target Asenapine (DG03100):  D02995<JP/US> Cerlapirdine (DG01337):  D10099 D10100 Idalopirdine (DG01878):  D10710 D10747 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Tiospirone hydrochloride:  D02688 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3362 (HTR6)    04024 cAMP signaling pathway     3362 (HTR6)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3362 (HTR6)    04082 Neuroactive ligand signaling     3362 (HTR6)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3362 (HTR6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3362 (HTR6) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3362 (HTR6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 DUF1385 Motif Other DBs NCBI-GeneID:  3362 NCBI-ProteinID:  NP_000862 OMIM:  601109 HGNC:  5301 Ensembl:  ENSG00000158748 UniProt:  P50406 Structure PDBPDBj LinkDB All DBs Position 1:19664875..19680966 Genome browser AA seq 440 aa AA seqDB search MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF FNIDPAEPELRPHPLGIPTN NT seq 1323 nt NT seq  +upstreamnt  +downstreamnt atggtcccagagccgggcccaaccgccaatagcaccccggcctggggggcagggccgccg tcggccccggggggcagcggctgggtggcggccgcgctgtgcgtggtcatcgcgctgacg gcggcggccaactcgctgctgatcgcgctcatctgcactcagcccgcgctgcgcaacacg tccaacttcttcctggtgtcgctcttcacgtctgacctgatggtggggctggtggtgatg ccgccggccatgctgaacgcgctgtacgggcgctgggtgctggcgcgcggcctctgcctg ctctggaccgccttcgacgtgatgtgctgcagcgcctccatcctcaacctctgcctcatc agcctggaccgctacctgctcatcctctcgccgctgcgctacaagctgcgcatgacgccc ctgcgtgccctggccctagtcctgggcgcctggagcctcgccgctctcgcctccttcctg cccctgctgctgggctggcacgagctgggccacgcacggccacccgtccctggccagtgc cgcctgctggccagcctgccttttgtccttgtggcgtcgggcctcaccttcttcctgccc tcgggtgccatatgcttcacctactgcaggatcctgctagctgcccgcaagcaggccgtg caggtggcctccctcaccaccggcatggccagtcaggcctcggagacgctgcaggtgccc aggaccccacgcccaggggtggagtctgctgacagcaggcgtctagccacgaagcacagc aggaaggccctgaaggccagcctgacgctgggcatcctgctgggcatgttctttgtgacc tggttgcccttctttgtggccaacatagtccaggccgtgtgcgactgcatctccccaggc ctcttcgatgtcctcacatggctgggttactgtaacagcaccatgaaccccatcatctac ccactcttcatgcgggacttcaagcgggcgctgggcaggttcctgccatgtccacgctgt ccccgggagcgccaggccagcctggcctcgccatcactgcgcacctctcacagcggcccc cggcccggccttagcctacagcaggtgctgccgctgcccctgccgccggactcagattcg gactcagacgcaggctcaggcggctcctcgggcctgcggctcacggcccagctgctgctt cctggcgaggccacccaggaccccccgctgcccaccagggccgctgccgccgtcaatttc ttcaacatcgaccccgcggagcccgagctgcggccgcatccacttggcatccccacgaac tga

Homo sapiens (human): 3363 Help Entry 3363              CDS       T01001                                  Symbol HTR7, 5-HT7 Name (RefSeq) 5-hydroxytryptamine receptor 7   KO K04163   5-hydroxytryptamine receptor 7 Organism hsa  Homo sapiens (human) Pathway hsa04014   Ras signaling pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse Drug target Asenapine (DG03100):  D02995<JP/US> Methysergide (DG00835):  D00681 D02357 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     3363 (HTR7)    04020 Calcium signaling pathway     3363 (HTR7)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3363 (HTR7)    04082 Neuroactive ligand signaling     3363 (HTR7)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3363 (HTR7)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3363 (HTR7) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3363 (HTR7) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx DUF7471 Motif Other DBs NCBI-GeneID:  3363 NCBI-ProteinID:  NP_062873 OMIM:  182137 HGNC:  5302 Ensembl:  ENSG00000148680 UniProt:  P34969 Structure PDBPDBj LinkDB All DBs Position 10:complement(90740823..90858039) Genome browser AA seq 479 aa AA seqDB search MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atgatggacgttaacagcagcggccgcccggacctctacgggcacctccgctctttcctt ctgccagaagtggggcgcgggctgcccgacttgagccccgacggtggcgccgacccggtc gcgggctcctgggcgccgcacctgctgagcgaggtgacagccagcccggcgcccacctgg gacgcgcccccggacaatgcctccggctgtggggaacagatcaactacggcagagtcgag aaagttgtgatcggctccatcctgacgctcatcacgctgctgacgatcgcgggcaactgc ctggtggtgatctccgtgtgcttcgtcaagaagctccgccagccctccaactacctgatc gtgtccctggcgctggccgacctctcggtggctgtggcggtcatgcccttcgtcagcgtc accgacctcatcgggggcaagtggatctttggacactttttctgtaatgtcttcatcgcc atggacgtcatgtgctgcacggcctcgatcatgaccctgtgcgtgatcagcattgacagg taccttgggatcacaaggcccctcacataccctgtgaggcagaatgggaaatgcatggcg aagatgattctctccgtctggcttctctccgcctccatcaccttacctccactctttgga tgggctcagaatgtaaatgatgataaggtgtgcttgatcagccaggactttggctatacg atttactctaccgcagtggcattttatatccccatgtccgtcatgcttttcatgtactac cagatttacaaggctgccaggaagagtgctgccaaacacaagtttcctggcttccctcga gtggagccagacagcgtcatcgccctgaatggcatagtgaagctccagaaggaggtggaa gagtgtgcaaacctttcgagactcctcaagcatgaaaggaaaaacatctccatctttaag cgagaacagaaagcagccaccaccctggggatcatcgtcggggcctttaccgtgtgctgg ctgccatttttcctcctctcgacagccagacccttcatctgtggcacttcctgcagctgc atcccactgtgggtggagaggacatttctgtggctaggctatgcaaactctctcattaac ccttttatatatgccttcttcaaccgggacctgaggaccacctatcgcagcctgctccag tgccagtaccggaatatcaaccggaagctctcagctgcaggcatgcatgaagccctgaag cttgctgagaggccagagagacctgagtttgtgctgagggcctgcacaaggagggtgctg ttgagaccagaaaagaggccaccggtatctgtgtgggtgctacaatctccagaccatcac aattggttagcagacaaaatgctgactactgtagaaaaaaaggtcatgattcatgattga

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