Homo sapiens (human): 356
Help
Entry
356 CDS
T01001
Symbol
FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A
Name
(RefSeq) Fas ligand
KO
K04389
tumor necrosis factor ligand superfamily member 6
Organism
hsa
Homo sapiens (human)
Pathway
hsa01524
Platinum drug resistance
hsa04010
MAPK signaling pathway
hsa04014
Ras signaling pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04068
FoxO signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04210
Apoptosis
hsa04217
Necroptosis
hsa04650
Natural killer cell mediated cytotoxicity
hsa04722
Neurotrophin signaling pathway
hsa04932
Non-alcoholic fatty liver disease
hsa04936
Alcoholic liver disease
hsa04940
Type I diabetes mellitus
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05130
Pathogenic Escherichia coli infection
hsa05142
Chagas disease
hsa05143
African trypanosomiasis
hsa05160
Hepatitis C
hsa05161
Hepatitis B
hsa05162
Measles
hsa05163
Human cytomegalovirus infection
hsa05164
Influenza A
hsa05165
Human papillomavirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05320
Autoimmune thyroid disease
hsa05330
Allograft rejection
hsa05332
Graft-versus-host disease
hsa05417
Lipid and atherosclerosis
Network
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06231
Apoptosis (cancer)
nt06263
Hepatocellular carcinoma
nt06460
Alzheimer disease
nt06463
Parkinson disease
nt06466
Pathways of neurodegeneration
nt06524
Apoptosis
nt06527
Necroptosis
Element
N00146
Crosstalk between extrinsic and intrinsic apoptotic pathways
N00448
HIV Tat/Nef to crosstalk between extrinsic and intrinsic apoptotic pathways
N00532
HBV HBx to Egr-mediated transcription
N01056
FAS-JNK signaling pathway
N01632
FASLG-RIPK1/3 signaling pathway
Disease
H00108
Autoimmune lymphoproliferative syndromes
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
356 (FASLG)
04014 Ras signaling pathway
356 (FASLG)
04068 FoxO signaling pathway
356 (FASLG)
04151 PI3K-Akt signaling pathway
356 (FASLG)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
356 (FASLG)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
356 (FASLG)
04217 Necroptosis
356 (FASLG)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
356 (FASLG)
09156 Nervous system
04722 Neurotrophin signaling pathway
356 (FASLG)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
356 (FASLG)
05205 Proteoglycans in cancer
356 (FASLG)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
356 (FASLG)
05161 Hepatitis B
356 (FASLG)
05160 Hepatitis C
356 (FASLG)
05164 Influenza A
356 (FASLG)
05162 Measles
356 (FASLG)
05168 Herpes simplex virus 1 infection
356 (FASLG)
05163 Human cytomegalovirus infection
356 (FASLG)
05165 Human papillomavirus infection
356 (FASLG)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
356 (FASLG)
09174 Infectious disease: parasitic
05142 Chagas disease
356 (FASLG)
05143 African trypanosomiasis
356 (FASLG)
09163 Immune disease
05320 Autoimmune thyroid disease
356 (FASLG)
05330 Allograft rejection
356 (FASLG)
05332 Graft-versus-host disease
356 (FASLG)
09164 Neurodegenerative disease
05022 Pathways of neurodegeneration - multiple diseases
356 (FASLG)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
356 (FASLG)
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
356 (FASLG)
04936 Alcoholic liver disease
356 (FASLG)
04932 Non-alcoholic fatty liver disease
356 (FASLG)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
356 (FASLG)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
356 (FASLG)
04052 Cytokines and neuropeptides [BR:
hsa04052
]
356 (FASLG)
04090 CD molecules [BR:
hsa04090
]
356 (FASLG)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
356 (FASLG)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Tumor necrosis fators
356 (FASLG)
CD molecules [BR:
hsa04090
]
Proteins
356 (FASLG)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TNF
Motif
Other DBs
NCBI-GeneID:
356
NCBI-ProteinID:
NP_000630
OMIM:
134638
HGNC:
11936
Ensembl:
ENSG00000117560
UniProt:
P48023
Q53ZZ1
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:172659103..172666876
Genome browser
AA seq
281 aa
AA seq
DB search
MQQPFNYPYPQIYWVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPP
PPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQ
MHTASSLEKQIGHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGG
LVINETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWA
RSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL
NT seq
846 nt
NT seq
+upstream
nt +downstream
nt
atgcagcagcccttcaattacccatatccccagatctactgggtggacagcagtgccagc
tctccctgggcccctccaggcacagttcttccctgtccaacctctgtgcccagaaggcct
ggtcaaaggaggccaccaccaccaccgccaccgccaccactaccacctccgccgccgccg
ccaccactgcctccactaccgctgccacccctgaagaagagagggaaccacagcacaggc
ctgtgtctccttgtgatgtttttcatggttctggttgccttggtaggattgggcctgggg
atgtttcagctcttccacctacagaaggagctggcagaactccgagagtctaccagccag
atgcacacagcatcatctttggagaagcaaataggccaccccagtccaccccctgaaaaa
aaggagctgaggaaagtggcccatttaacaggcaagtccaactcaaggtccatgcctctg
gaatgggaagacacctatggaattgtcctgctttctggagtgaagtataagaagggtggc
cttgtgatcaatgaaactgggctgtactttgtatattccaaagtatacttccggggtcaa
tcttgcaacaacctgcccctgagccacaaggtctacatgaggaactctaagtatccccag
gatctggtgatgatggaggggaagatgatgagctactgcactactgggcagatgtgggcc
cgcagcagctacctgggggcagtgttcaatcttaccagtgctgatcatttatatgtcaac
gtatctgagctctctctggtcaattttgaggaatctcagacgtttttcggcttatataag
ctctaa
Homo sapiens (human): 8743
Help
Entry
8743 CDS
T01001
Symbol
TNFSF10, APO2L, Apo-2L, CD253, TANCR, TL2, TNLG6A, TRAIL
Name
(RefSeq) TNF superfamily member 10
KO
K04721
tumor necrosis factor ligand superfamily member 10
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04061
Viral protein interaction with cytokine and cytokine receptor
hsa04068
FoxO signaling pathway
hsa04210
Apoptosis
hsa04217
Necroptosis
hsa04650
Natural killer cell mediated cytotoxicity
hsa05130
Pathogenic Escherichia coli infection
hsa05132
Salmonella infection
hsa05164
Influenza A
hsa05417
Lipid and atherosclerosis
Network
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06231
Apoptosis (cancer)
nt06263
Hepatocellular carcinoma
nt06460
Alzheimer disease
nt06466
Pathways of neurodegeneration
nt06524
Apoptosis
nt06527
Necroptosis
Element
N00146
Crosstalk between extrinsic and intrinsic apoptotic pathways
N01631
TNFSF10-RIPK1/3 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
8743 (TNFSF10)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
8743 (TNFSF10)
04061 Viral protein interaction with cytokine and cytokine receptor
8743 (TNFSF10)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
8743 (TNFSF10)
04217 Necroptosis
8743 (TNFSF10)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
8743 (TNFSF10)
09160 Human Diseases
09172 Infectious disease: viral
05164 Influenza A
8743 (TNFSF10)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
8743 (TNFSF10)
05132 Salmonella infection
8743 (TNFSF10)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
8743 (TNFSF10)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
8743 (TNFSF10)
04052 Cytokines and neuropeptides [BR:
hsa04052
]
8743 (TNFSF10)
04090 CD molecules [BR:
hsa04090
]
8743 (TNFSF10)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
8743 (TNFSF10)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Tumor necrosis fators
8743 (TNFSF10)
CD molecules [BR:
hsa04090
]
Proteins
8743 (TNFSF10)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TNF
Motif
Other DBs
NCBI-GeneID:
8743
NCBI-ProteinID:
NP_003801
OMIM:
603598
HGNC:
11925
Ensembl:
ENSG00000121858
UniProt:
P50591
Q6IBA9
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(172505508..172523430)
Genome browser
AA seq
281 aa
AA seq
DB search
MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
NT seq
846 nt
NT seq
+upstream
nt +downstream
nt
atggctatgatggaggtccaggggggacccagcctgggacagacctgcgtgctgatcgtg
atcttcacagtgctcctgcagtctctctgtgtggctgtaacttacgtgtactttaccaac
gagctgaagcagatgcaggacaagtactccaaaagtggcattgcttgtttcttaaaagaa
gatgacagttattgggaccccaatgacgaagagagtatgaacagcccctgctggcaagtc
aagtggcaactccgtcagctcgttagaaagatgattttgagaacctctgaggaaaccatt
tctacagttcaagaaaagcaacaaaatatttctcccctagtgagagaaagaggtcctcag
agagtagcagctcacataactgggaccagaggaagaagcaacacattgtcttctccaaac
tccaagaatgaaaaggctctgggccgcaaaataaactcctgggaatcatcaaggagtggg
cattcattcctgagcaacttgcacttgaggaatggtgaactggtcatccatgaaaaaggg
ttttactacatctattcccaaacatactttcgatttcaggaggaaataaaagaaaacaca
aagaacgacaaacaaatggtccaatatatttacaaatacacaagttatcctgaccctata
ttgttgatgaaaagtgctagaaatagttgttggtctaaagatgcagaatatggactctat
tccatctatcaagggggaatatttgagcttaaggaaaatgacagaatttttgtttctgta
acaaatgagcacttgatagacatggaccatgaagccagtttttttggggcctttttagtt
ggctaa
DBGET
integrated database retrieval system
