N00145 |
|
TNF | → | TNFRSF1A | → | (RIPK1+TRADD+TRAF2.. | → | FADD | → | CASP8 | → | (CASP3,CASP7) |
N00146 |
|
| | (FASLG,TNFSF10) | → | (FAS,TNFRSF10B) | → | FADD | → | (CASP8,CASP10) | → | BID | → | (BAX,BAK1) | → | CYCS | = | APAF1 | → | CASP9 | → | (CASP3,CASP7) |
N00166 |
|
| | | | | | vFLIP | ⊣ | CASP8P3 |
N00164 |
|
| | | | | | | | | | vBCL2 | ⊣ | (BAX,BAK1) |
N00165 |
|
| | | | | | | | | | | | | | | | | | vIAP | ⊣ | CASP3 |
N00098 |
|
| | | | | | | | (PMAIP1,BBC3,BAD,B.. | ⊣ | (BCL2,BCL2L1) | ⊣ | (BAX,BAK1) | → | CYCS | = | APAF1 | → | CASP9 | → | (CASP3,CASP7) |
N00100 |
|
| | | | | | | | | | BCL2* | ⊣ | BAX | → | CYCS | = | APAF1 | → | CASP9 | → | (CASP3,CASP7) |
N00099 |
|
| | | | | | | | | | | | BAX* | ⌿ | CYCS |
N00101 |
|
| | | | | | | | | | | | | | CASP3 | → | DCC | → | (CASP9+APPL1) | → | CASP3 |
N00102 |
|
| | | | | | | | | | | | | | CASP3 | ⌿ | DCC* | ⌿ | (CASP9+APPL1) |
|