KEGG   Homo sapiens (human): 5424
Entry
5424              CDS       T01001                                 
Symbol
POLD1, CDC2, CRCS10, IMD120, MDPL, POLD
Name
(RefSeq) DNA polymerase delta 1, catalytic subunit
  KO
K02327  DNA polymerase delta subunit 1 [EC:2.7.7.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03030  DNA replication
hsa03410  Base excision repair
hsa03420  Nucleotide excision repair
hsa03430  Mismatch repair
hsa03440  Homologous recombination
Network
nt06502  Nucleotide excision repair
nt06503  Mismatch repair
nt06504  Base excision repair
nt06506  Double-strand break repair
nt06509  DNA replication
  Element
N01431  Core NER reaction
N01432  Mismatch repair
N01436  Long patch BER
N01452  Homologous recombination
N01472  Okazaki fragment maturation
Disease
H00020  Colorectal cancer
H00093  Combined immunodeficiency
H01623  MDPL syndrome
H02568  Polymerase proofreading-associated polyposis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    5424 (POLD1)
   03410 Base excision repair
    5424 (POLD1)
   03420 Nucleotide excision repair
    5424 (POLD1)
   03430 Mismatch repair
    5424 (POLD1)
   03440 Homologous recombination
    5424 (POLD1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    5424 (POLD1)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5424 (POLD1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     5424 (POLD1)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase delta complex
    5424 (POLD1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase delta complex
      5424 (POLD1)
   MMR (mismatch excision repair)
    DNA polymerase delta complex
     5424 (POLD1)
SSDB
Motif
Pfam: DNA_pol_B DNA_pol_B_exo1 zf-C4pol POL3_N REV3_N DNA_pol_B_2
Other DBs
NCBI-GeneID: 5424
NCBI-ProteinID: NP_001243778
OMIM: 174761
HGNC: 9175
Ensembl: ENSG00000062822
UniProt: P28340
Structure
LinkDB
Position
19:50384323..50418018
AA seq 1107 aa
MDGKRRPGPGPGVPPKRARGGLWDDDDAPRPSQFEEDLALMEEMEAEHRLQEQEEEELQS
VLEGVADGQVPPSAIDPRWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRG
SVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGR
ELTGPAVLAVELCSRESMFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPS
FAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLKEKATQCQLEADVLWSDVVSHPP
EGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPC
APILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPF
LGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFH
FLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTG
VPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGYYDVPIAT
LDFSSLYPSIMMAHNLCYTTLLRPGTAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQIL
ENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSV
TGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAAD
WVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLV
ANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAH
VELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQ
QLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVLS
HQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFY
MRKKVRKDLEDQEQLLRRFGPPGPEAW
NT seq 3324 nt   +upstreamnt  +downstreamnt
atggatggcaagcggcggccaggcccagggcccggggtgcccccaaagcgggcccgtggg
ggcctctgggatgatgatgatgcacctcggccatcccaattcgaggaggacctggcactg
atggaggagatggaggcagaacacaggctgcaggagcaggaggaggaggagctgcagtca
gtcctggagggggttgcagacgggcaggtcccaccatcagccatagatcctcgctggctt
cggcccacaccaccagcgctggacccccagacagagcccctcatcttccaacagttggag
attgaccattatgtgggcccagcgcagcctgtgcctggggggcccccaccatcccgcggc
tccgtgcctgtgctccgcgccttcggggtcaccgatgaggggttctctgtctgctgccac
atccacggcttcgctccctacttctacaccccagcgccccctggtttcgggcccgagcac
atgggtgacctgcaacgggagctgaacttggccatcagccgggacagtcgcggggggagg
gagctgactgggccggccgtgctggctgtggaactgtgctcccgagagagcatgtttggg
taccacgggcacggcccctccccgttcctgcgcatcaccgtggcgctgccgcgcctcgtg
gccccggcccgccgtctcctggaacagggcatccgtgtggcaggcctgggcacgcccagc
ttcgcgccctacgaggccaacgtcgactttgagatccggttcatggtggacacggacatc
gtcggctgcaactggctggagctcccagctgggaaatacgccctgaggctgaaggagaag
gctacgcagtgccagctggaggcggacgtgctgtggtctgacgtggtcagtcacccaccg
gaagggccatggcagcgcattgcgcccttgcgcgtgctcagcttcgatatcgagtgcgcc
ggccgcaaaggcatcttccctgagcctgagcgggaccctgtcatccagatctgctcgctg
ggcctgcgctggggggagccggagcccttcctacgcctggcgctcaccctgcggccctgt
gcccccatcctgggtgccaaggtgcagagctacgagaaggaggaggacctgctgcaggcc
tggtccaccttcatccgtatcatggaccccgacgtgatcaccggttacaacatccagaac
ttcgaccttccgtacctcatctctcgggcccagaccctcaaggtacaaacattccctttc
ctgggccgtgtggccggcctttgctccaacatccgggactcttcattccagtccaagcag
acgggccggcgggacaccaaggttgtcagcatggtgggccgcgtgcagatggacatgctg
caggtgctgctgcgggagtacaagctccgctcctacacgctcaatgccgtgagcttccac
ttcctgggcgagcagaaggaggacgtgcagcacagcatcatcaccgacctgcagaatggg
aacgaccagacccgccgccgcctggctgtgtactgcctgaaggatgcctacctgccactg
cggctgctggagcggctcatggtgctggtgaacgccgtggagatggcgagggtcactggc
gtgcccctcagctacctgctcagtcgtggccagcaggtcaaggtcgtatcccagctgttg
cggcaggccatgcacgaggggctgctgatgcccgtggtgaagtcagagggcggcgaggac
tacacgggagccactgtcatcgagcccctcaaagggtactacgacgtccccatcgccacc
ctggacttctcctcgctgtacccgtccatcatgatggcccacaacctgtgttacaccacg
ctccttcggcccgggactgcacagaaactgggcctgactgaggatcagttcatcaggacc
cccaccggggacgagtttgtgaagacctcagtgcggaaggggctgctgccccagatcctg
gagaacctgctcagtgcccggaagagggccaaggccgagctggccaaggagacagacccc
ctccggcgccaggtcctggatggacggcagctggcgctgaaggtgagcgccaactccgta
tacggcttcactggcgcccaggtgggcaagttgccgtgcctggagatctcacagagcgtc
acggggttcggacgtcagatgatcgagaaaaccaagcagctggtggagtctaagtacaca
gtggagaatggctacagcaccagtgccaaggtggtgtatggtgacactgactccgtcatg
tgccgattcggcgtgtcctcggtggctgaggcgatggccctggggcgggaggccgcggac
tgggtgtcaggtcacttcccgtcgcccatccggctggagtttgagaaggtctacttccca
tacctgcttatcagcaagaagcgctacgcgggcctgctcttctcctcccggcccgacgcc
cacgaccgcatggactgcaagggcctggaggccgtgcgcagggacaactgccccctcgtg
gccaacctggtcactgcctcactgcgccgcctgctcatcgaccgagaccctgagggcgcg
gtggctcacgcacaggacgtcatctcggacctgctgtgcaaccgcatcgatatctcccag
ctggtcatcaccaaggagctgacccgcgcggcctccgactatgccggcaagcaggcccac
gtggagctggccgagaggatgaggaagcgggaccccgggagtgcgcccagcctgggcgac
cgcgtcccctacgtgatcatcagtgccgccaagggtgtggccgcctacatgaagtcggag
gacccgctgttcgtgctggagcacagcctgcccattgacacgcagtactacctggagcag
cagctggccaagcccctcctgcgcatcttcgagcccatcctgggcgagggccgtgccgag
gctgtgctactgcggggggaccacacgcgctgcaagacggtgctcacgggcaaggtgggc
ggcctcctggccttcgccaaacgccgcaactgctgcattggctgccgcacagtgctcagc
caccagggagccgtgtgtgagttctgccagccccgggagtctgagctgtatcagaaggag
gtatcccatctgaatgccctggaggagcgcttctcgcgcctctggacgcagtgccagcgc
tgccagggcagcctgcacgaggacgtcatctgcaccagccgggactgccccatcttctac
atgcgcaagaaggtgcggaaggacctggaagaccaggagcagctcctgcggcgcttcgga
ccccctggacctgaggcctggtga

KEGG   Homo sapiens (human): 5425
Entry
5425              CDS       T01001                                 
Symbol
POLD2
Name
(RefSeq) DNA polymerase delta 2, accessory subunit
  KO
K02328  DNA polymerase delta subunit 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03030  DNA replication
hsa03410  Base excision repair
hsa03420  Nucleotide excision repair
hsa03430  Mismatch repair
hsa03440  Homologous recombination
Network
nt06502  Nucleotide excision repair
nt06503  Mismatch repair
nt06504  Base excision repair
nt06506  Double-strand break repair
nt06509  DNA replication
  Element
N01431  Core NER reaction
N01432  Mismatch repair
N01436  Long patch BER
N01452  Homologous recombination
N01472  Okazaki fragment maturation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    5425 (POLD2)
   03410 Base excision repair
    5425 (POLD2)
   03420 Nucleotide excision repair
    5425 (POLD2)
   03430 Mismatch repair
    5425 (POLD2)
   03440 Homologous recombination
    5425 (POLD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    5425 (POLD2)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5425 (POLD2)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase delta complex
    5425 (POLD2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase delta complex
      5425 (POLD2)
   MMR (mismatch excision repair)
    DNA polymerase delta complex
     5425 (POLD2)
SSDB
Motif
Pfam: DNA_pol_E_B DNA_pol_D_N
Other DBs
NCBI-GeneID: 5425
NCBI-ProteinID: NP_001120690
OMIM: 600815
HGNC: 9176
Ensembl: ENSG00000106628
UniProt: P49005
Structure
LinkDB
Position
7:complement(44114680..44124325)
AA seq 469 aa
MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
NT seq 1410 nt   +upstreamnt  +downstreamnt
atgttttctgagcaggctgcccagagggcccacactctactgtccccaccatcagccaac
aatgccacctttgcccgggtgccagtggcaacctacaccaactcctcacaacccttccgg
ctaggagagcgcagctttagccggcagtatgcccacatttatgccacccgcctcatccaa
atgagacccttcctggagaaccgggcccagcagcactggggcagtggagtgggagtgaag
aagctgtgtgaactgcagcctgaggagaagtgctgtgtggtgggcactctgttcaaggcc
atgccgctgcagccctccatcctgcgggaggtcagcgaggagcacaacctgctcccccag
cctcctcggagtaaatacatacacccagatgacgagctggtcttggaagatgaactgcag
cgtatcaaactaaaaggcaccattgacgtgtcaaagctggttacggggactgtcctggct
gtgtttggctccgtgagagacgacgggaagtttctggtggaggactattgctttgctgac
cttgctccccagaagcccgcacccccacttgacacagataggtttgtgctactggtgtcc
ggcctgggcctgggtggcggtggaggcgagagcctgctgggcacccagctgctggtggat
gtggtgacggggcagcttggggacgaaggggagcagtgcagcgccgcccacgtctcccgg
gttatcctcgctggcaacctcctcagccacagcacccagagcagggattctatcaataag
gccaaatacctcaccaagaaaacccaggcagccagcgtggaggctgttaagatgctggat
gagatcctcctgcagctgagcgcctcagtgcccgtggacgtgatgccaggcgagtttgat
cccaccaattacacgctcccccagcagcccctccacccctgcatgttcccgctggccact
gcctactccacgctccagctggtcaccaacccctaccaggccaccattgatggagtcaga
tttttggggacatcaggacagaacgtgagtgacattttccgatacagcagcatggaggat
cacttggagatcctggagtggaccctgcgggtccgtcacatcagccccacagcccctgac
actctaggttgttaccccttctacaaaactgacccgttcatcttcccagagtgcccgcat
gtctacttttgtggcaacacccccagctttggctccaaaatcatccgaggtcctgaggac
cagacagtgctgttggtgactgtccctgacttcagtgccacgcagaccgcctgccttgtg
aacctgcgcagcctggcctgccagcccatcagcttctcgggcttcggggcagaggacgat
gacctgggaggcctggggctgggcccctga

KEGG   Homo sapiens (human): 10714
Entry
10714             CDS       T01001                                 
Symbol
POLD3, IMD122, P66, P68, PPP1R128
Name
(RefSeq) DNA polymerase delta 3, accessory subunit
  KO
K03504  DNA polymerase delta subunit 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03030  DNA replication
hsa03410  Base excision repair
hsa03420  Nucleotide excision repair
hsa03430  Mismatch repair
hsa03440  Homologous recombination
Network
nt06502  Nucleotide excision repair
nt06503  Mismatch repair
nt06504  Base excision repair
nt06506  Double-strand break repair
nt06509  DNA replication
  Element
N01431  Core NER reaction
N01432  Mismatch repair
N01436  Long patch BER
N01450  Break induced replication
N01452  Homologous recombination
N01472  Okazaki fragment maturation
Disease
H00091  T-B+Severe combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    10714 (POLD3)
   03410 Base excision repair
    10714 (POLD3)
   03420 Nucleotide excision repair
    10714 (POLD3)
   03430 Mismatch repair
    10714 (POLD3)
   03440 Homologous recombination
    10714 (POLD3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    10714 (POLD3)
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    10714 (POLD3)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    10714 (POLD3)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     10714 (POLD3)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase delta complex
    10714 (POLD3)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase delta complex
      10714 (POLD3)
   MMR (mismatch excision repair)
    DNA polymerase delta complex
     10714 (POLD3)
SSDB
Motif
Pfam: CDC27
Other DBs
NCBI-GeneID: 10714
NCBI-ProteinID: NP_006582
OMIM: 611415
HGNC: 20932
Ensembl: ENSG00000077514
UniProt: Q15054
Structure
LinkDB
Position
11:74592582..74669341
AA seq 466 aa
MADQLYLENIDEFVTDQNKIVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVT
YLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYD
ILKSNLQNCSKFSAIQCAAAVPRAPAESSSSSKKFEQSHLHMSSETQANNELTTNGHGPP
ASKQVSQQPKGIMGMFASKAAAKTQETNKETKTEAKEVTNASAAGNKAPGKGNMMSNFFG
KAAMNKFKVNLDSEQAVKEEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKKR
GKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPPLE
PVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVTEKVYESESCTDSEEELNMK
TSSVHRPPAMTVKKEPREERKGPKKGTAALGKANRQVSITGFFQRK
NT seq 1401 nt   +upstreamnt  +downstreamnt
atggcggaccagctttatctggaaaatatagacgagttcgtcacggaccaaaacaagatc
gtgacatacaaatggctgagctatacactaggggttcatgttaaccaggccaaacagatg
ctgtatgattatgttgaaaggaaacgaaaagaaaattcaggagcccaactgcatgttacc
tacttggtgtctggcagtctcattcagaatggacattcctgccacaaggttgcagtagtg
agagaagataaattggaagcagtgaagtccaagctagctgtgactgccagcatccatgtg
tacagcatccagaaagccatgctaaaggacagtgggcctctgttcaatactgactatgac
atccttaaaagcaacttgcagaactgcagcaaatttagtgctatacaatgtgcagctgcc
gtccctagagctcctgctgaatcctcttcgtcttccaaaaagtttgagcagtcacatctt
cacatgtcaagtgagacacaagccaacaatgagctgaccaccaatggtcatggcccacct
gcatccaagcaggtttcccagcagcccaaaggaattatgggaatgtttgcctccaaagct
gctgctaaaacccaagaaaccaacaaggaaacgaaaacagaggctaaagaagtaacaaat
gcatctgcagcaggcaacaaggcaccagggaaagggaatatgatgagcaacttttttgga
aaagctgctatgaataaatttaaagtcaatttggactcagaacaagcagtgaaagaagaa
aaaatagtggagcagcctacagtgtctgtcacggaaccaaagctggcaactcctgcaggc
ctgaaaaaatccagcaaaaaagcagagcctgttaaggtgctgcagaaggaaaaaaaaagg
gggaagcgagtagcattatctgatgatgagacaaaggaaactgaaaacatgaggaaaaag
aggagaagaatcaaacttcctgaatctgatagcagtgaagatgaagtctttccagactct
cctggggcttatgaagctgagtcaccatccccacctcctcctccgtctccacctcttgaa
ccagtgccaaagactgagcctgaacctccttctgtcaagagctcaagtggagaaaacaaa
agaaaacgaaaacgcgtactaaaatctaaaacttacctggatggggaaggctgcatagtg
actgaaaaagtctacgagagtgaatcctgcacagatagtgaagaggagcttaacatgaag
acatcctcagtacacagaccccctgccatgactgtgaaaaaagaacccagagaggaacga
aagggccccaagaaagggactgctgctctgggcaaagccaacagacaggtgtccattact
ggcttcttccagaggaaataa

KEGG   Homo sapiens (human): 57804
Entry
57804             CDS       T01001                                 
Symbol
POLD4, POLDS, p12
Name
(RefSeq) DNA polymerase delta 4, accessory subunit
  KO
K03505  DNA polymerase delta subunit 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03030  DNA replication
hsa03410  Base excision repair
hsa03420  Nucleotide excision repair
hsa03430  Mismatch repair
hsa03440  Homologous recombination
Network
nt06502  Nucleotide excision repair
nt06503  Mismatch repair
nt06504  Base excision repair
nt06506  Double-strand break repair
nt06509  DNA replication
  Element
N01431  Core NER reaction
N01432  Mismatch repair
N01436  Long patch BER
N01452  Homologous recombination
N01472  Okazaki fragment maturation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    57804 (POLD4)
   03410 Base excision repair
    57804 (POLD4)
   03420 Nucleotide excision repair
    57804 (POLD4)
   03430 Mismatch repair
    57804 (POLD4)
   03440 Homologous recombination
    57804 (POLD4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    57804 (POLD4)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    57804 (POLD4)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase delta complex
    57804 (POLD4)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase delta complex
      57804 (POLD4)
   MMR (mismatch excision repair)
    DNA polymerase delta complex
     57804 (POLD4)
SSDB
Motif
Pfam: DNA_pol_delta_4
Other DBs
NCBI-GeneID: 57804
NCBI-ProteinID: NP_066996
OMIM: 611525
HGNC: 14106
Ensembl: ENSG00000175482
UniProt: Q9HCU8 Q6NSD7
Structure
LinkDB
Position
11:complement(67350765..67353596)
AA seq 107 aa
MGRKRLITDSYPVVKRREGPAGHSKGELAPELGEEPQPRDEEEAELELLRQFDLAWQYGP
CTGITRLQRWCRAKQMGLEPPPEVWQVLKTHPGDPRFQCSLWHLYPL
NT seq 324 nt   +upstreamnt  +downstreamnt
atgggccggaagcggctcatcactgattcctacccggttgtgaagaggagggaggggccc
gctgggcacagcaagggggagctggcacccgagctaggggaggagccccagccccgcgac
gaggaggaagcggagctggagctgctgaggcagtttgacctggcctggcagtacgggccc
tgcaccgggatcacacggctgcagcgctggtgtcgggccaagcagatgggcttggagcct
cccccagaggtgtggcaggtgctgaagacccaccccggagacccccgcttccagtgcagt
ctctggcatctctatcccctatga

KEGG   Homo sapiens (human): 5111
Entry
5111              CDS       T01001                                 
Symbol
PCNA, ATLD2
Name
(RefSeq) proliferating cell nuclear antigen
  KO
K04802  proliferating cell nuclear antigen
Organism
hsa  Homo sapiens (human)
Pathway
hsa03030  DNA replication
hsa03410  Base excision repair
hsa03420  Nucleotide excision repair
hsa03430  Mismatch repair
hsa04110  Cell cycle
hsa04530  Tight junction
hsa05161  Hepatitis B
Network
nt06162  Hepatitis B virus (HBV)
nt06263  Hepatocellular carcinoma
nt06502  Nucleotide excision repair
nt06503  Mismatch repair
nt06504  Base excision repair
nt06506  Double-strand break repair
nt06509  DNA replication
  Element
N00544  HBV HBx to CREB-mediated transcription
N01431  Core NER reaction
N01432  Mismatch repair
N01436  Long patch BER
N01452  Homologous recombination
N01471  Origin unwinding and elongation
N01472  Okazaki fragment maturation
Disease
H02014  Ataxia-telangiectasia-like syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    5111 (PCNA)
   03410 Base excision repair
    5111 (PCNA)
   03420 Nucleotide excision repair
    5111 (PCNA)
   03430 Mismatch repair
    5111 (PCNA)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    5111 (PCNA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5111 (PCNA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    5111 (PCNA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    5111 (PCNA)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5111 (PCNA)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   Other elongation factors
    5111 (PCNA)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     5111 (PCNA)
   MMR (mismatch excision repair)
    Other MMR factors
     5111 (PCNA)
  TLS (translesion DNA synthesis) factors
   Other TLS factors
    5111 (PCNA)
SSDB
Motif
Pfam: PCNA_C PCNA_N Rad1 Rad9 Hus1 AMA-1 FmdE
Other DBs
NCBI-GeneID: 5111
NCBI-ProteinID: NP_002583
OMIM: 176740
HGNC: 8729
Ensembl: ENSG00000132646
UniProt: P12004
Structure
LinkDB
Position
20:complement(5114953..5126622)
AA seq 261 aa
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTY
RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD
LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI
KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK
IADMGHLKYYLAPKIEDEEGS
NT seq 786 nt   +upstreamnt  +downstreamnt
atgttcgaggcgcgcctggtccagggctccatcctcaagaaggtgttggaggcactcaag
gacctcatcaacgaggcctgctgggatattagctccagcggtgtaaacctgcagagcatg
gactcgtcccacgtctctttggtgcagctcaccctgcggtctgagggcttcgacacctac
cgctgcgaccgcaacctggccatgggcgtgaacctcaccagtatgtccaaaatactaaaa
tgcgccggcaatgaagatatcattacactaagggccgaagataacgcggataccttggcg
ctagtatttgaagcaccaaaccaggagaaagtttcagactatgaaatgaagttgatggat
ttagatgttgaacaacttggaattccagaacaggagtacagctgtgtagtaaagatgcct
tctggtgaatttgcacgtatatgccgagatctcagccatattggagatgctgttgtaatt
tcctgtgcaaaagacggagtgaaattttctgcaagtggagaacttggaaatggaaacatt
aaattgtcacagacaagtaatgtcgataaagaggaggaagctgttaccatagagatgaat
gaaccagttcaactaacttttgcactgaggtacctgaacttctttacaaaagccactcca
ctctcttcaacggtgacactcagtatgtctgcagatgtaccccttgttgtagagtataaa
attgcggatatgggacacttaaaatactacttggctcccaagatcgaggatgaagaagga
tcttag

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