Homo sapiens (human): 6117
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Entry
6117 CDS
T01001
Symbol
RPA1, HSSB, MST075, PFBMFT6, REPA1, RF-A, RP-A, RPA70
Name
(RefSeq) replication protein A1
KO
K07466
replication factor A1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03030
DNA replication
hsa03420
Nucleotide excision repair
hsa03430
Mismatch repair
hsa03440
Homologous recombination
hsa03460
Fanconi anemia pathway
Network
nt06502
Nucleotide excision repair
nt06503
Mismatch repair
nt06506
Double-strand break repair
nt06508
Interstrand crosslink repair
nt06509
DNA replication
Element
N01431
Core NER reaction
N01432
Mismatch repair
N01446
DNA end resection and RPA loading
N01451
ATR signaling
N01452
Homologous recombination
N01466
Homologous recombination in ICLR
N01471
Origin unwinding and elongation
N01539
RAD51 -dsDNA destabilization
Disease
H02569
Pulmonary fibrosis and/or bone marrow failure, telomere-related
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
6117 (RPA1)
03420 Nucleotide excision repair
6117 (RPA1)
03430 Mismatch repair
6117 (RPA1)
03440 Homologous recombination
6117 (RPA1)
03460 Fanconi anemia pathway
6117 (RPA1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
6117 (RPA1)
03032 DNA replication proteins [BR:
hsa03032
]
6117 (RPA1)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
6117 (RPA1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Zinc finger
Cys2His2 others
6117 (RPA1)
DNA replication proteins [BR:
hsa03032
]
Eukaryotic type
DNA Replication Elongation Factors
RPA (replication protein A)
6117 (RPA1)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
NER (nucleotide excision repair)
RPA (replication factor A)
6117 (RPA1)
MMR (mismatch excision repair)
6117 (RPA1)
DSBR (double strand breaks repair)
HR (homologous recombination)
6117 (RPA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Rep_fac-A_C
REPA_OB_2
Rep-A_N
tRNA_anti-codon
DUF223
IBR
Motif
Other DBs
NCBI-GeneID:
6117
NCBI-ProteinID:
NP_002936
OMIM:
179835
HGNC:
10289
Ensembl:
ENSG00000132383
Pharos:
P27694
(Tchem)
UniProt:
P27694
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:1830005..1900082
Genome browser
AA seq
616 aa
AA seq
DB search
MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLAT
QLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELEVLKSAEAVGVKIGNPVPYNE
GLGQPQVAPPAPAASPAASSRPQPQNGSSGMGSTVSKAYGASKTFGKAAGPSLSHTSGGT
QSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNE
QVDKFFPLIEVNKVYYFSKGTLKIANKQFTAVKNDYEMTFNNETSVMPCEDDHHLPTVQF
DFTGIDDLENKSKDSLVDIIGICKSYEDATKITVRSNNREVAKRNIYLMDTSGKVVTATL
WGEDADKFDGSRQPVLAIKGARVSDFGGRSLSVLSSSTIIANPDIPEAYKLRGWFDAEGQ
ALDGVSISDLKSGGVGGSNTNWKTLYEVKSENLGQGDKPDYFSSVATVVYLRKENCMYQA
CPTQDCNKKVIDQQNGLYRCEKCDTEFPNFKYRMILSVNIADFQENQWVTCFQESAEAIL
GQNAAYLGELKDKNEQAFEEVFQNANFRSFIFRVRVKVETYNDESRIKATVMDVKPVDYR
EYGRRLVMSIRRSALM
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atggtcggccaactgagcgagggggccattgcggccatcatgcagaagggggatacaaac
ataaagcccatcctccaagtcatcaacatccgtcccattactacggggaatagtccgccg
cgttatcgactgctcatgagtgatggattgaacactctatcctctttcatgttggcgaca
cagttgaaccctctcgtggaggaagaacaattgtccagcaactgtgtatgccagattcac
agatttattgtgaacactctgaaagacggaaggagagtagttatcttgatggaattagaa
gttttgaagtcagctgaagcagttggagtgaagattggcaatccagtgccctataatgaa
ggactcgggcagccgcaagtagctcctccagcgccagcagccagcccagcagcaagcagc
aggccccagccgcagaatggaagctcgggaatgggttctactgtttctaaggcttatggt
gcttcaaagacatttggaaaagctgcaggtcccagcctgtcacacacttctgggggaaca
cagtccaaagtggtgcccattgccagcctcactccttaccagtccaagtggaccatttgt
gctcgtgttaccaacaaaagtcagatccgtacctggagcaactcccgaggggaagggaag
cttttctccctagaactggttgacgaaagtggtgaaatccgagctacagctttcaatgag
caagtggacaagttctttcctcttattgaagtgaacaaggtgtattatttctcgaaaggc
accctgaagattgctaacaagcagttcacagctgttaaaaatgactacgagatgaccttc
aataacgagacttccgtcatgccctgtgaggacgaccatcatttacctacggttcagttt
gatttcacggggattgatgacctcgagaacaagtcgaaagactcacttgtagacatcatc
gggatctgcaagagctatgaagacgccactaaaatcacagtgaggtctaacaacagagaa
gttgccaagaggaatatctacttgatggacacatccgggaaggtggtgactgctacactg
tggggggaagatgctgataaatttgatggttctagacagcccgtgttggctatcaaagga
gcccgagtctctgatttcggtggacggagcctctccgtgctgtcttcaagcactatcatt
gcgaatcctgacatcccagaggcctataagcttcgtggatggtttgacgcagaaggacaa
gccttagatggtgtttccatctctgatctaaagagcggcggagtcggagggagtaacacc
aactggaaaaccttgtatgaggtcaaatccgagaacctgggccaaggcgacaagccggac
tactttagttctgtggccacagtggtgtatcttcgcaaagagaactgcatgtaccaagcc
tgcccgactcaggactgcaataagaaagtgattgatcaacagaatggattgtaccgctgt
gagaagtgcgacaccgaatttcccaatttcaagtaccgcatgatcctgtcagtaaatatt
gcagattttcaagagaatcagtgggtgacttgtttccaggagtctgctgaagctatcctt
ggacaaaatgctgcttatcttggggaattaaaagacaagaatgaacaggcatttgaagaa
gttttccagaatgccaacttccgatctttcatattcagagtcagggtcaaagtggagacc
tacaacgacgagtctcgaattaaggccactgtgatggacgtgaagcccgtggactacaga
gagtatggccgaaggctggtcatgagcatcaggagaagtgcattgatgtga
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