Homo sapiens (human): 650
Help
Entry
650 CDS
T01001
Symbol
BMP2, BDA2, BMP2A, SSFSC, SSFSC1
Name
(RefSeq) bone morphogenetic protein 2
KO
K21283
bone morphogenetic protein 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04350
TGF-beta signaling pathway
hsa04390
Hippo signaling pathway
hsa05200
Pathways in cancer
hsa05217
Basal cell carcinoma
Network
nt06217
HH signaling (cancer)
nt06269
Basal cell carcinoma
nt06507
TGFB signaling
Element
N00010
Mutation-inactivated PTCH1 to Hedgehog signaling pathway
N00017
Mutation-activated SMO to Hedgehog signaling pathway
N01428
BMP signaling pathway, BMP antagonist
N01453
BMP signaling pathway
N01458
BMP-HAMP signaling pathway
Disease
H00482
Brachydactyly
H02481
Syndromic disorder with short stature
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
650 (BMP2)
04390 Hippo signaling pathway
650 (BMP2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
650 (BMP2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
650 (BMP2)
09162 Cancer: specific types
05217 Basal cell carcinoma
650 (BMP2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
650 (BMP2)
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
650 (BMP2)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Transforming growth factors (RSTK binding)
650 (BMP2)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Morphogens
650 (BMP2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Peptidase_M24_C
Motif
Other DBs
NCBI-GeneID:
650
NCBI-ProteinID:
NP_001191
OMIM:
112261
HGNC:
1069
Ensembl:
ENSG00000125845
UniProt:
P12643
C8C060
Structure
PDB
LinkDB
All DBs
Position
20:6767686..6780246
Genome browser
AA seq
396 aa
AA seq
DB search
MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSM
FGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEE
LPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPA
TANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVS
KRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP
LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKAC
CVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
atggtggccgggacccgctgtcttctagcgttgctgcttccccaggtcctcctgggcggc
gcggctggcctcgttccggagctgggccgcaggaagttcgcggcggcgtcgtcgggccgc
ccctcatcccagccctctgacgaggtcctgagcgagttcgagttgcggctgctcagcatg
ttcggcctgaaacagagacccacccccagcagggacgccgtggtgcccccctacatgcta
gacctgtatcgcaggcactcaggtcagccgggctcacccgccccagaccaccggttggag
agggcagccagccgagccaacactgtgcgcagcttccaccatgaagaatctttggaagaa
ctaccagaaacgagtgggaaaacaacccggagattcttctttaatttaagttctatcccc
acggaggagtttatcacctcagcagagcttcaggttttccgagaacagatgcaagatgct
ttaggaaacaatagcagtttccatcaccgaattaatatttatgaaatcataaaacctgca
acagccaactcgaaattccccgtgaccagacttttggacaccaggttggtgaatcagaat
gcaagcaggtgggaaagttttgatgtcacccccgctgtgatgcggtggactgcacaggga
cacgccaaccatggattcgtggtggaagtggcccacttggaggagaaacaaggtgtctcc
aagagacatgttaggataagcaggtctttgcaccaagatgaacacagctggtcacagata
aggccattgctagtaacttttggccatgatggaaaagggcatcctctccacaaaagagaa
aaacgtcaagccaaacacaaacagcggaaacgccttaagtccagctgtaagagacaccct
ttgtacgtggacttcagtgacgtggggtggaatgactggattgtggctcccccggggtat
cacgccttttactgccacggagaatgcccttttcctctggctgatcatctgaactccact
aatcatgccattgttcagacgttggtcaactctgttaactctaagattcctaaggcatgc
tgtgtcccgacagaactcagtgctatctcgatgctgtaccttgacgagaatgaaaaggtt
gtattaaagaactatcaggacatggttgtggagggttgtgggtgtcgctag
Homo sapiens (human): 652
Help
Entry
652 CDS
T01001
Symbol
BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Name
(RefSeq) bone morphogenetic protein 4
KO
K04662
bone morphogenetic protein 4
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04350
TGF-beta signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04919
Thyroid hormone signaling pathway
hsa05200
Pathways in cancer
hsa05217
Basal cell carcinoma
hsa05418
Fluid shear stress and atherosclerosis
Network
nt06217
HH signaling (cancer)
nt06269
Basal cell carcinoma
nt06507
TGFB signaling
Element
N00010
Mutation-inactivated PTCH1 to Hedgehog signaling pathway
N00017
Mutation-activated SMO to Hedgehog signaling pathway
N01428
BMP signaling pathway, BMP antagonist
N01453
BMP signaling pathway
Disease
H00516
Cleft lip and/or cleft palate
H02170
Microphthalmia, syndromic
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
652 (BMP4)
04390 Hippo signaling pathway
652 (BMP4)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
652 (BMP4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
652 (BMP4)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
652 (BMP4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
652 (BMP4)
09162 Cancer: specific types
05217 Basal cell carcinoma
652 (BMP4)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
652 (BMP4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
652 (BMP4)
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
652 (BMP4)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Transforming growth factors (RSTK binding)
652 (BMP4)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Morphogens
652 (BMP4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Motif
Other DBs
NCBI-GeneID:
652
NCBI-ProteinID:
NP_001193
OMIM:
112262
HGNC:
1071
Ensembl:
ENSG00000125378
UniProt:
P12644
Q53XC5
LinkDB
All DBs
Position
14:complement(53949736..53956891)
Genome browser
AA seq
408 aa
AA seq
DB search
MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
HHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFHRINI
YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
NT seq
1227 nt
NT seq
+upstream
nt +downstream
nt
atgattcctggtaaccgaatgctgatggtcgttttattatgccaagtcctgctaggaggc
gcgagccatgctagtttgatacctgagacggggaagaaaaaagtcgccgagattcagggc
cacgcgggaggacgccgctcagggcagagccatgagctcctgcgggacttcgaggcgaca
cttctgcagatgtttgggctgcgccgccgcccgcagcctagcaagagtgccgtcattccg
gactacatgcgggatctttaccggcttcagtctggggaggaggaggaagagcagatccac
agcactggtcttgagtatcctgagcgcccggccagccgggccaacaccgtgaggagcttc
caccacgaagaacatctggagaacatcccagggaccagtgaaaactctgcttttcgtttc
ctctttaacctcagcagcatccctgagaacgaggtgatctcctctgcagagcttcggctc
ttccgggagcaggtggaccagggccctgattgggaaaggggcttccaccgtataaacatt
tatgaggttatgaagcccccagcagaagtggtgcctgggcacctcatcacacgactactg
gacacgagactggtccaccacaatgtgacacggtgggaaacttttgatgtgagccctgcg
gtccttcgctggacccgggagaagcagccaaactatgggctagccattgaggtgactcac
ctccatcagactcggacccaccagggccagcatgtcaggattagccgatcgttacctcaa
gggagtgggaattgggcccagctccggcccctcctggtcacctttggccatgatggccgg
ggccatgccttgacccgacgccggagggccaagcgtagccctaagcatcactcacagcgg
gccaggaagaagaataagaactgccggcgccactcgctctatgtggacttcagcgatgtg
ggctggaatgactggattgtggccccaccaggctaccaggccttctactgccatggggac
tgcccctttccactggctgaccacctcaactcaaccaaccatgccattgtgcagaccctg
gtcaattctgtcaattccagtatccccaaagcctgttgtgtgcccactgaactgagtgcc
atctccatgctgtacctggatgagtatgataaggtggtactgaaaaattatcaggagatg
gtagtagagggatgtgggtgccgctga
Homo sapiens (human): 654
Help
Entry
654 CDS
T01001
Symbol
BMP6, IO, VGR, VGR1
Name
(RefSeq) bone morphogenetic protein 6
KO
K16620
bone morphogenetic protein 6
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04350
TGF-beta signaling pathway
hsa04390
Hippo signaling pathway
hsa04913
Ovarian steroidogenesis
Network
nt06507
TGFB signaling
Element
N01428
BMP signaling pathway, BMP antagonist
N01453
BMP signaling pathway
N01458
BMP-HAMP signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
654 (BMP6)
04390 Hippo signaling pathway
654 (BMP6)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
654 (BMP6)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
654 (BMP6)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
654 (BMP6)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Transforming growth factors (RSTK binding)
654 (BMP6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Motif
Other DBs
NCBI-GeneID:
654
NCBI-ProteinID:
NP_001709
OMIM:
112266
HGNC:
1073
Ensembl:
ENSG00000153162
UniProt:
P22004
Q4VBA3
B4DUF7
Structure
PDB
LinkDB
All DBs
Position
6:7726099..7881728
Genome browser
AA seq
513 aa
AA seq
DB search
MPGLGRRAQWLCWWWGLLCSCCGPPPLRPPLPAAAAAAAGGQLLGDGGSPGRTEQPPPSP
QSSSGFLYRRLKTQEKREMQKEILSVLGLPHRPRPLHGLQQPQPPALRQQEEQQQQQQLP
RGEPPPGRLKSAPLFMLDLYNALSADNDEDGASEGERQQSWPHEAASSSQRRQPPPGAAH
PLNRKSLLAPGSGSGGASPLTSAQDSAFLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKF
NLSQIPEGEVVTAAEFRIYKDCVMGSFKNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWA
SEEGWLEFDITATSNLWVVTPQHNMGLQLSVVTRDGVHVHPRAAGLVGRDGPYDKQPFMV
AFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYVS
FQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAP
TKLNAISVLYFDDNSNVILKKYRNMVVRACGCH
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgccggggctggggcggagggcgcagtggctgtgctggtggtgggggctgctgtgcagc
tgctgcgggcccccgccgctgcggccgcccttgcccgctgccgcggccgccgccgccggg
gggcagctgctgggggacggcgggagccccggccgcacggagcagccgccgccgtcgccg
cagtcctcctcgggcttcctgtaccggcggctcaagacgcaggagaagcgggagatgcag
aaggagatcttgtcggtgctggggctcccgcaccggccccggcccctgcacggcctccaa
cagccgcagcccccggcgctccggcagcaggaggagcagcagcagcagcagcagctgcct
cgcggagagccccctcccgggcgactgaagtccgcgcccctcttcatgctggatctgtac
aacgccctgtccgccgacaacgacgaggacggggcgtcggagggggagaggcagcagtcc
tggccccacgaagcagccagctcgtcccagcgtcggcagccgcccccgggcgccgcgcac
ccgctcaaccgcaagagccttctggcccccggatctggcagcggcggcgcgtccccactg
accagcgcgcaggacagcgccttcctcaacgacgcggacatggtcatgagctttgtgaac
ctggtggagtacgacaaggagttctcccctcgtcagcgacaccacaaagagttcaagttc
aacttatcccagattcctgagggtgaggtggtgacggctgcagaattccgcatctacaag
gactgtgttatggggagttttaaaaaccaaacttttcttatcagcatttatcaagtctta
caggagcatcagcacagagactctgacctgtttttgttggacacccgtgtagtatgggcc
tcagaagaaggctggctggaatttgacatcacggccactagcaatctgtgggttgtgact
ccacagcataacatggggcttcagctgagcgtggtgacaagggatggagtccacgtccac
ccccgagccgcaggcctggtgggcagagacggcccttacgacaagcagcccttcatggtg
gctttcttcaaagtgagtgaggtgcacgtgcgcaccaccaggtcagcctccagccggcgc
cgacaacagagtcgtaatcgctctacccagtcccaggacgtggcgcgggtctccagtgct
tcagattacaacagcagtgaattgaaaacagcctgcaggaagcatgagctgtatgtgagt
ttccaagacctgggatggcaggactggatcattgcacccaagggctatgctgccaattac
tgtgatggagaatgctccttcccactcaacgcacacatgaatgcaaccaaccacgcgatt
gtgcagaccttggttcaccttatgaaccccgagtatgtccccaaaccgtgctgtgcgcca
actaagctaaatgccatctcggttctttactttgatgacaactccaatgtcattctgaaa
aaatacaggaatatggttgtaagagcttgtggatgccactaa
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integrated database retrieval system
