Homo sapiens (human): 6751 Help Entry 6751              CDS       T01001                                  Gene name SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R Definition (RefSeq) somatostatin receptor 1   KO K04217   somatostatin receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04935   Growth hormone synthesis, secretion and action Drug target Pasireotide (DG00503):  D10147 D10497<US> D10566<JP/US> Seglitide acetate:  D05812 Somatostatin:  D07431 Veldoreotide:  D11192 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     6751 (SSTR1)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     6751 (SSTR1)  09150 Organismal Systems   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     6751 (SSTR1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     6751 (SSTR1) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Somatostatin     6751 (SSTR1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7tm_4 T2SSM Piezo_RRas_bdg Motif Other DBs NCBI-GeneID:  6751 NCBI-ProteinID:  NP_001040 OMIM:  182451 HGNC:  11330 Ensembl:  ENSG00000139874 Vega:  OTTHUMG00000140249 Pharos:  P30872(Tclin) UniProt:  P30872 Q86SW9 LinkDB All DBs Position 14q21.1 AA seq 391 aa AA seqDB search MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS RAYSVEDFQPENLESGGVFRNGTCTSRITTL NT seq 1176 nt NT seq  +upstreamnt  +downstreamnt atgttccccaatggcaccgcctcctctccttcctcctctcctagccccagcccgggcagc tgcggcgaaggcggcggcagcaggggccccggggccggcgctgcggacggcatggaggag ccagggcgaaatgcgtcccagaacgggaccttgagcgagggccagggcagcgccatcctg atctctttcatctactccgtggtgtgcctggtggggctgtgtgggaactctatggtcatc tacgtgatcctgcgctatgccaagatgaagacggccaccaacatctacatcctaaatctg gccattgctgatgagctgctcatgctcagcgtgcccttcctagtcacctccacgttgttg cgccactggcccttcggtgcgctgctctgccgcctcgtgctcagcgtggacgcggtcaac atgttcaccagcatctactgtctgactgtgctcagcgtggaccgctacgtggccgtggtg catcccatcaaggcggcccgctaccgccggcccaccgtggccaaggtagtaaacctgggc gtgtgggtgctatcgctgctcgtcatcctgcccatcgtggtcttctctcgcaccgcggcc aacagcgacggcacggtggcttgcaacatgctcatgccagagcccgctcaacgctggctg gtgggcttcgtgttgtacacatttctcatgggcttcctgctgcccgtgggggctatctgc ctgtgctacgtgctcatcattgctaagatgcgcatggtggccctcaaggccggctggcag cagcgcaagcgctcggagcgcaagatcaccttaatggtgatgatggtggtgatggtgttt gtcatctgctggatgcctttctacgtggtgcagctggtcaacgtgtttgctgagcaggac gacgccacggtgagtcagctgtcggtcatcctcggctatgccaacagctgcgccaacccc atcctctatggctttctctcagacaacttcaagcgctctttccaacgcatcctatgcctc agctggatggacaacgccgcggaggagccggttgactattacgccaccgcgctcaagagc cgtgcctacagtgtggaagacttccaacctgagaacctggagtccggcggcgtcttccgt aatggcacctgcacgtcccggatcacgacgctctga

Homo sapiens (human): 6752 Help Entry 6752              CDS       T01001                                  Gene name SSTR2 Definition (RefSeq) somatostatin receptor 2   KO K04218   somatostatin receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04935   Growth hormone synthesis, secretion and action hsa04971   Gastric acid secretion Drug target Copper Cu 64 dotatate:  D11882<US> Edotreotide gallium Ga-68:  D11651<US> Indium (111In) pentetreotide:  D02108<JP/US> Lanreotide:  D04666<JP/US> Lutetium (177Lu) oxodotreotide:  D11033<JP/US> Octreotide (DG00501):  D00442 D02250<JP> D05230 D06495<US> D11204 Pasireotide (DG00503):  D10147 D10497<US> D10566<JP/US> Seglitide acetate:  D05812 Somatostatin:  D07431 Tidutamab:  D11845 Vapreotide (DG00502):  D06281 D09988 Veldoreotide:  D11192 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     6752 (SSTR2)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     6752 (SSTR2)  09150 Organismal Systems   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     6752 (SSTR2)   09154 Digestive system    04971 Gastric acid secretion     6752 (SSTR2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     6752 (SSTR2) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Somatostatin     6752 (SSTR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv FtsK_4TM Motif Other DBs NCBI-GeneID:  6752 NCBI-ProteinID:  NP_001041 OMIM:  182452 HGNC:  11331 Ensembl:  ENSG00000180616 Vega:  OTTHUMG00000178343 Pharos:  P30874(Tclin) UniProt:  P30874 LinkDB All DBs Position 17q25.1 AA seq 369 aa AA seqDB search MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL LNGDLQTSI NT seq 1110 nt NT seq  +upstreamnt  +downstreamnt atggacatggcggatgagccactcaatggaagccacacatggctatccattccatttgac ctcaatggctctgtggtgtcaaccaacacctcaaaccagacagagccgtactatgacctg acaagcaatgcagtcctcacattcatctattttgtggtctgcatcattgggttgtgtggc aacacacttgtcatttatgtcatcctccgctatgccaagatgaagaccatcaccaacatt tacatcctcaacctggccatcgcagatgagctcttcatgctgggtctgcctttcttggct atgcaggtggctctggtccactggccctttggcaaggccatttgccgggtggtcatgact gtggatggcatcaatcagttcaccagcatcttctgcctgacagtcatgagcatcgaccga tacctggctgtggtccaccccatcaagtcggccaagtggaggagaccccggacggccaag atgatcaccatggctgtgtggggagtctctctgctggtcatcttgcccatcatgatatat gctgggctccggagcaaccagtgggggagaagcagctgcaccatcaactggccaggtgaa tctggggcttggtacacagggttcatcatctacactttcattctggggttcctggtaccc ctcaccatcatctgtctttgctacctgttcattatcatcaaggtgaagtcctctggaatc cgagtgggctcctctaagaggaagaagtctgagaagaaggtcacccgaatggtgtccatc gtggtggctgtcttcatcttctgctggcttcccttctacatattcaacgtttcttccgtc tccatggccatcagccccaccccagcccttaaaggcatgtttgactttgtggtggtcctc acctatgctaacagctgtgccaaccctatcctatatgccttcttgtctgacaacttcaag aagagcttccagaatgtcctctgcttggtcaaggtgagcggcacagatgatggggagcgg agtgacagtaagcaggacaaatcccggctgaatgagaccacggagacccagaggaccctc ctcaatggagacctccaaaccagtatctga

Homo sapiens (human): 6753 Help Entry 6753              CDS       T01001                                  Gene name SSTR3, SS-3-R, SS3-R, SS3R, SSR-28 Definition (RefSeq) somatostatin receptor 3   KO K04219   somatostatin receptor 3 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04935   Growth hormone synthesis, secretion and action Drug target Indium (111In) pentetreotide:  D02108<JP/US> Pasireotide (DG00503):  D10147 D10497<US> D10566<JP/US> Seglitide acetate:  D05812 Somatostatin:  D07431 Veldoreotide:  D11192 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     6753 (SSTR3)  09150 Organismal Systems   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     6753 (SSTR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     6753 (SSTR3) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Somatostatin     6753 (SSTR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7TM_GPCR_Srw Rab5ip Motif Other DBs NCBI-GeneID:  6753 NCBI-ProteinID:  NP_001042 OMIM:  182453 HGNC:  11332 Ensembl:  ENSG00000278195 Vega:  OTTHUMG00000150537 Pharos:  P32745(Tclin) UniProt:  P32745 LinkDB All DBs Position 22q13.1 AA seq 418 aa AA seqDB search MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL NT seq 1257 nt NT seq  +upstreamnt  +downstreamnt atggacatgcttcatccatcatcggtgtccacgacctcagaacctgagaatgcctcctcg gcctggcccccagatgccaccctgggcaacgtgtcggcgggcccaagcccggcagggctg gccgtcagtggcgttctgatccccctggtctacctggtggtgtgcgtggtgggcctgctg ggtaactcgctggtcatctatgtggtcctgcggcacacggccagcccttcagtcaccaac gtctacatcctcaacctggcgctggccgacgagctcttcatgctggggctgcccttcctg gccgcccagaacgccctgtcctactggcccttcggctccctcatgtgccgcctggtcatg gcggtggatggcatcaaccagttcaccagcatattctgcctgactgtcatgagcgtggac cgctacctggccgtggtacatcccacccgctcggcccgctggcgcacagctccggtggcc cgcacggtcagcgcggctgtgtgggtggcctcagccgtggtggtgctgcccgtggtggtc ttctcgggagtgccccgcggcatgagcacctgccacatgcagtggcccgagccggcggcg gcctggcgagccggcttcatcatctacacggccgcactgggcttcttcgggccgctgctg gtcatctgcctctgctacctgctcatcgtggtgaaggtgcgctcagctgggcgccgggtg tgggcaccctcgtgccagcggcggcggcgctccgaacgcagggtcacgcgcatggtggtg gccgtggtggcgctcttcgtgctctgctggatgcccttctacgtgctcaacatcgtcaac gtggtgtgcccactgcccgaggagcctgccttctttgggctctacttcctggtggtggcg ctgccctatgccaacagctgtgccaaccccatcctttatggcttcctctcctaccgcttc aagcagggcttccgcagggtcctgctgcggccctcccgccgtgtgcgcagccaggagccc actgtggggcccccggagaagactgaggaggaggatgaggaggaggaggatggggaggag agcagggaggggggcaaggggaaggagatgaacggccgggtcagccagatcacgcagcct ggcaccagcgggcaggagcggccgcccagcagagtggccagcaaggagcagcagctccta ccccaagaggcttccactggggagaagtccagcacgatgcgcatcagctacctgtag

Homo sapiens (human): 6754 Help Entry 6754              CDS       T01001                                  Gene name SSTR4, SS-4-R, SS4-R, SS4R Definition (RefSeq) somatostatin receptor 4   KO K04220   somatostatin receptor 4 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction Drug target Seglitide acetate:  D05812 Somatostatin:  D07431 Veldoreotide:  D11192 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     6754 (SSTR4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     6754 (SSTR4) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Somatostatin     6754 (SSTR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7TM_GPCR_Srw 7tm_4 Motif Other DBs NCBI-GeneID:  6754 NCBI-ProteinID:  NP_001043 OMIM:  182454 HGNC:  11333 Ensembl:  ENSG00000132671 Vega:  OTTHUMG00000032054 Pharos:  P31391(Tclin) UniProt:  P31391 LinkDB All DBs Position 20p11.21 AA seq 388 aa AA seqDB search MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCR AVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRA VALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILS YANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCM CPPLPCQQEALQPEPGRKRIPLTRTTTF NT seq 1167 nt NT seq  +upstreamnt  +downstreamnt atgagcgccccctcgacgctgccccccgggggcgaggaagggctggggacggcctggccc tctgcagccaatgccagtagcgctccggcggaggcggaggaggcggtggcggggcccggg gacgcgcgggcggcgggcatggtcgctatccagtgcatctacgcgctggtgtgcctggtg gggctggtgggcaacgccctggtcatcttcgtgatccttcgctacgccaagatgaagacg gctaccaacatctacctgctcaacctggccgtagccgacgagctcttcatgctgagcgtg cccttcgtggcctcgtcggccgccctgcgccactggcccttcggctccgtgctgtgccgc gcggtgctcagcgtcgacggcctcaacatgttcaccagcgtcttctgtctcaccgtgctc agcgtggaccgctacgtggccgtggtgcaccctctgcgcgcggcgacctaccggcggccc agcgtggccaagctcatcaacctgggcgtgtggctggcatccctgttggtcactctcccc atcgccatcttcgcagacaccagaccggctcgcggcggccaggccgtggcctgcaacctg cagtggccacacccggcctggtcggcagtcttcgtggtctacactttcctgctgggcttc ctgctgcccgtgctggccattggcctgtgctacctgctcatcgtgggcaagatgcgcgcc gtggccctgcgcgctggctggcagcagcgcaggcgctcggagaagaaaatcaccaggctg gtgctgatggtcgtggtcgtctttgtgctctgctggatgcctttctacgtggtgcagctg ctgaacctcttcgtgaccagccttgatgccaccgtcaaccacgtgtcccttatccttagc tatgccaacagctgcgccaaccccattctctatggcttcctctccgacaacttccgccga ttcttccagcgggttctctgcctgcgctgctgcctcctggaaggtgctggaggtgctgag gaggagcccctggactactatgccactgctctcaagagcaaaggtggggcagggtgcatg tgccccccactcccctgccagcaggaagccctgcaaccagaacccggccgcaagcgcatc cccctcaccaggaccaccaccttctga

Homo sapiens (human): 6755 Help Entry 6755              CDS       T01001                                  Gene name SSTR5, SS-5-R Definition (RefSeq) somatostatin receptor 5   KO K04221   somatostatin receptor 5 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04935   Growth hormone synthesis, secretion and action Drug target Indium (111In) pentetreotide:  D02108<JP/US> Lanreotide:  D04666<JP/US> Pasireotide (DG00503):  D10147 D10497<US> D10566<JP/US> Seglitide acetate:  D05812 Somatostatin:  D07431 Vapreotide (DG00502):  D06281 D09988 Veldoreotide:  D11192 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     6755 (SSTR5)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     6755 (SSTR5)  09150 Organismal Systems   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     6755 (SSTR5)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     6755 (SSTR5) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Somatostatin     6755 (SSTR5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7TM_GPCR_Srw Motif Other DBs NCBI-GeneID:  6755 NCBI-ProteinID:  NP_001044 OMIM:  182455 HGNC:  11334 Ensembl:  ENSG00000162009 Vega:  OTTHUMG00000047842 Pharos:  P35346(Tclin) UniProt:  P35346 LinkDB All DBs Position 16p13.3 AA seq 364 aa AA seqDB search MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ TSKL NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt atggagcccctgttcccagcctccacgcccagctggaacgcctcctccccgggggctgcc tctggaggcggtgacaacaggacgctggtggggccggcgccctcggcaggggcccgggcg gtgctggtgcccgtgctgtacctgctggtgtgtgcggccgggctgggcgggaacacgctg gtcatctacgtggtgctgcgcttcgccaagatgaagaccgtcaccaacatctacattctc aacctggcagtggccgacgtcctgtacatgctggggctgcctttcctggccacgcagaac gccgcgtccttctggcccttcggccccgtcctgtgccgcctggtcatgacgctggacggc gtcaaccagttcaccagtgtcttctgcctgacagtcatgagcgtggaccgctacctggca gtggtgcacccgctgagctcggcccgctggcgccgcccgcgtgtggccaagctggcgagc gccgcggcctgggtcctgtctctgtgcatgtcgctgccgctcctggtgttcgcggacgtg caggagggcggtacctgcaacgccagctggccggagcccgtggggctgtggggcgccgtc ttcatcatctacacggccgtgctgggcttcttcgcgccgctgctggtcatctgcctgtgc tacctgctcatcgtggtgaaggtgagggcggcgggcgtgcgcgtgggctgcgtgcggcgg cgctcggagcggaaggtgacgcgcatggtgttggtggtggtgctggtgtttgcgggatgt tggctgcccttcttcaccgtcaacatcgtcaacctggccgtggcgctgccccaggagccc gcctccgccggcctctacttcttcgtggtcatcctctcctacgccaacagctgtgccaac cccgtcctctacggcttcctctctgacaacttccgccagagcttccagaaggttctgtgc ctccgcaagggctctggtgccaaggacgctgacgccacggagccgcgtccagacaggatc cggcagcagcaggaggccacgccacccgcgcaccgcgccgcagccaacgggcttatgcag accagcaagctgtga

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