Homo sapiens (human): 7879
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Entry
7879 CDS
T01001
Symbol
RAB7A, CMT2B, PRO2706, RAB7
Name
(RefSeq) RAB7A, member RAS oncogene family
KO
K07897
Ras-related protein Rab-7A
Organism
hsa
Homo sapiens (human)
Pathway
hsa04137
Mitophagy - animal
hsa04140
Autophagy - animal
hsa04144
Endocytosis
hsa04145
Phagosome
hsa04148
Efferocytosis
hsa05132
Salmonella infection
hsa05146
Amoebiasis
hsa05152
Tuberculosis
Network
nt06181
Salmonella
nt06532
Autophagy
nt06536
Mitophagy
Element
N01295
Rab7-regulated microtubule minus-end directed transport
N01296
Salmonella SopD2 to Rab7-regulated microtubule minus-end directed transport
N01300
Tethering of late endosomes and lysosomes
N01301
Salmonella SifA to Tethering of late endosomes and lysosomes
N01721
Autophagosome and lysosome fusion, tethering factor
N01760
Endosomal Rab cycles
Disease
H00264
Charcot-Marie-Tooth disease
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
7879 (RAB7A)
04145 Phagosome
7879 (RAB7A)
04140 Autophagy - animal
7879 (RAB7A)
04137 Mitophagy - animal
7879 (RAB7A)
04148 Efferocytosis
7879 (RAB7A)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
7879 (RAB7A)
05152 Tuberculosis
7879 (RAB7A)
09174 Infectious disease: parasitic
05146 Amoebiasis
7879 (RAB7A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
7879 (RAB7A)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
7879 (RAB7A)
04031 GTP-binding proteins [BR:
hsa04031
]
7879 (RAB7A)
Membrane trafficking [BR:
hsa04131
]
Endosome - Lysosome transport
Rab GTPases and associated proteins
Rab GTPases
7879 (RAB7A)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
7879 (RAB7A)
Exosomal proteins of other body fluids (saliva and urine)
7879 (RAB7A)
Exosomal proteins of colorectal cancer cells
7879 (RAB7A)
Exosomal proteins of bladder cancer cells
7879 (RAB7A)
GTP-binding proteins [BR:
hsa04031
]
Small (monomeric) G-proteins
Rab Family
Rab7/9 [OT]
7879 (RAB7A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ras
Roc
Arf
MMR_HSR1
GTP_EFTU
RsgA_GTPase
Gtr1_RagA
ATP_bind_1
cobW
nSTAND3
PduV-EutP
Septin
AAA_7
NTPase_1
AAA_22
AAA_16
AAA_24
G-alpha
AAA_5
ATPase_2
NACHT
AAA_14
NB-ARC
SRPRB
ATP-synt_ab
ABC_tran
Motif
Other DBs
NCBI-GeneID:
7879
NCBI-ProteinID:
NP_004628
OMIM:
602298
HGNC:
9788
Ensembl:
ENSG00000075785
Pharos:
P51149
(Tbio)
UniProt:
P51149
A0A158RFU6
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:128726183..128814798
Genome browser
AA seq
207 aa
AA seq
DB search
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ
IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPF
VVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEV
ELYNEFPEPIKLDKNDRAKASAESCSC
NT seq
624 nt
NT seq
+upstream
nt +downstream
nt
atgacctctaggaagaaagtgttgctgaaggttatcatcctgggagattctggagtcggg
aagacatcactcatgaaccagtatgtgaataagaaattcagcaatcagtacaaagccaca
ataggagctgactttctgaccaaggaggtgatggtggatgacaggctagtcacaatgcag
atatgggacacagcaggacaggaacggttccagtctctcggtgtggccttctacagaggt
gcagactgctgcgttctggtatttgatgtgactgcccccaacacattcaaaaccctagat
agctggagagatgagtttctcatccaggccagtccccgagatcctgaaaacttcccattt
gttgtgttgggaaacaagattgacctcgaaaacagacaagtggccacaaagcgggcacag
gcctggtgctacagcaaaaacaacattccctactttgagaccagtgccaaggaggccatc
aacgtggagcaggcgttccagacgattgcacggaatgcacttaagcaggaaacggaggtg
gagctgtacaacgaatttcctgaacctatcaaactggacaagaatgaccgggccaaggcc
tcggcagaaagctgcagttgctga
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