KEGG   Homo sapiens (human): 79885
Entry
79885             CDS       T01001                                 
Symbol
HDAC11, HD11
Name
(RefSeq) histone deacetylase 11
  KO
K11418  histone deacetylase 11 [EC:3.5.1.98]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04613  Neutrophil extracellular trap formation
hsa05034  Alcoholism
hsa05203  Viral carcinogenesis
Drug target
Abexinostat (DG01402): D10060 D10084
Belinostat: D08870<US>
Bocodepsin (DG03260): D12551 D12552
Entinostat: D09338
Givinostat (DG03284): D12742 D12743<US>
Mocetinostat (DG01404): D09357 D09641
Panobinostat (DG01403): D10019 D10319
Quisinostat (DG01407): D10321 D10322
Remetinostat: D10977
Romidepsin: D06637<JP/US>
Vorinostat: D06320<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    79885 (HDAC11)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    79885 (HDAC11)
  09165 Substance dependence
   05034 Alcoholism
    79885 (HDAC11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    79885 (HDAC11)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     79885 (HDAC11)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class IV HDACs
     79885 (HDAC11)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 79885
NCBI-ProteinID: NP_079103
OMIM: 607226
HGNC: 19086
Ensembl: ENSG00000163517
UniProt: Q96DB2
LinkDB
Position
3:13480306..13506416
AA seq 347 aa
MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
NT seq 1044 nt   +upstreamnt  +downstreamnt
atgctacacacaacccagctgtaccagcatgtgccagagacacgctggccaatcgtgtac
tcgccgcgctacaacatcaccttcatgggcctggagaagctgcatccctttgatgccgga
aaatggggcaaagtgatcaatttcctaaaagaagagaagcttctgtctgacagcatgctg
gtggaggcgcgggaggcctcggaggaggacctgctggtggtgcacacgaggcgctatctt
aatgagctcaagtggtcctttgctgttgctaccatcacagaaatcccccccgttatcttc
ctccccaacttccttgtgcagaggaaggtgctgaggccccttcggacccagacaggagga
accataatggcggggaagctggctgtggagcgaggctgggccatcaacgtggggggtggc
ttccaccactgctccagcgaccgtggcgggggcttctgtgcctatgcggacatcacgctc
gccatcaagtttctgtttgagcgtgtggagggcatctccagggctaccatcattgatctt
gatgcccatcagggcaatgggcatgagcgagacttcatggacgacaagcgtgtgtacatc
atggatgtctacaaccgccacatctacccaggggaccgctttgccaagcaggccatcagg
cggaaggtggagctggagtggggcacagaggatgatgagtacctggataaggtggagagg
aacatcaagaaatccctccaggagcacctgcccgacgtggtggtatacaatgcaggcacc
gacatcctcgagggggaccgccttggggggctgtccatcagcccagcgggcatcgtgaag
cgggatgagctggtgttccggatggtccgtggccgccgggtgcccatccttatggtgacc
tcaggcgggtaccagaagcgcacagcccgcatcattgctgactccatacttaatctgttt
ggcctggggctcattgggcctgagtcacccagcgtctccgcacagaactcagacacaccg
ctgcttccccctgcagtgccctga

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