Homo sapiens (human): 8318 Help Entry 8318              CDS       T01001                                  Symbol CDC45, CDC45L, CDC45L2, MGORS7, PORC-PI-1 Name (RefSeq) cell division cycle 45   KO K06628   cell division control protein 45 Organism hsa  Homo sapiens (human) Pathway hsa04110   Cell cycle Network nt06509  DNA replication   Element N01468   DNA replication licensing N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Disease H01889   Meier-Gorlin syndrome Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     8318 (CDC45)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     8318 (CDC45) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    Other initiation factors     8318 (CDC45) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  CDC45 Motif Other DBs NCBI-GeneID:  8318 NCBI-ProteinID:  NP_003495 OMIM:  603465 HGNC:  1739 Ensembl:  ENSG00000093009 UniProt:  O75419 Structure PDBPDBj LinkDB All DBs Position 22:19479466..19520612 Genome browser AA seq 566 aa AA seqDB search MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET AFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIK QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR RRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVT DVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARF KLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQT FSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAK KQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCS TKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHN HFDLSVIELKAEDRSKFLDALISLLS NT seq 1701 nt NT seq  +upstreamnt  +downstreamnt atgttcgtgtccgatttccgcaaagagttctacgaggtggtccagagccagagggtcctt ctcttcgtggcctcggacgtggatgctctgtgtgcgtgcaagatccttcaggccttgttc cagtgtgaccacgtgcaatatacgctggttccagtttctgggtggcaagaacttgaaact gcatttcttgagcataaagaacagtttcattattttattctcataaactgtggagctaat gtagacctattggatattcttcaacctgatgaagacactatattctttgtgtgtgacacc cataggccagtcaatgtcgtcaatgtatacaacgatacccagatcaaattactcattaaa caagatgatgaccttgaagttcccgcctatgaagacatcttcagggatgaagaggaggat gaagagcattcaggaaatgacagtgatgggtcagagccttctgagaagcgcacacggtta gaagaggagatagtggagcaaaccatgcggaggaggcagcggcgagagtgggaggcccgg agaagagacatcctctttgactacgagcagtatgaatatcatgggacatcgtcagccatg gtgatgtttgagctggcttggatgctgtccaaggacctgaatgacatgctgtggtgggcc atcgttggactaacagaccagtgggtgcaagacaagatcactcaaatgaaatacgtgact gatgttggtgtcctgcagcgccacgtttcccgccacaaccaccggaacgaggatgaggag aacacactctccgtggactgcacacggatctcctttgagtatgacctccgcctggtgctc taccagcactggtccctccatgacagcctgtgcaacaccagctataccgcagccaggttc aagctgtggtctgtgcatggacagaagcggctccaggagttccttgcagacatgggtctt cccctgaagcaggtgaagcagaagttccaggccatggacatctccttgaaggagaatttg cgggaaatgattgaagagtctgcaaataaatttgggatgaaggacatgcgcgtgcagact ttcagcattcattttgggttcaagcacaagtttctggccagcgacgtggtctttgccacc atgtctttgatggagagccccgagaaggatggctcagggacagatcacttcatccaggct ctggacagcctctccaggagtaacctggacaagctgtaccatggcctggaactcgccaag aagcagctgcgagccacccagcagaccattgccagctgcctttgcaccaacctcgtcatc tcccaggggcctttcctgtactgctctctcatggagggcactccagatgtcatgctgttc tctaggccggcatccctaagcctgctcagcaaacacctgctcaagtcctttgtgtgttcg acaaagaaccggcgctgcaaactgctgcccctggtgatggctgcccccctgagcatggag catggcacagtgaccgtggtgggcatccccccagagaccgacagctcggacaggaagaac ttttttgggagggcgtttgagaaggcagcggaaagcaccagctcccggatgctgcacaac cattttgacctctcagtaattgagctgaaagctgaggatcggagcaagtttctggacgca cttatttccctcctgtcctag

Homo sapiens (human): 4171 Help Entry 4171              CDS       T01001                                  Symbol MCM2, BM28, CCNL1, CDCL1, D3S3194, DFNA70, MITOTIN, cdc19 Name (RefSeq) minichromosome maintenance complex component 2   KO K02540   DNA replication licensing factor MCM2 [EC:5.6.2.3] Organism hsa  Homo sapiens (human) Pathway hsa03030   DNA replication hsa04110   Cell cycle Network nt06506  Double-strand break repair nt06509  DNA replication   Element N01450   Break induced replication N01468   DNA replication licensing N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Disease H00604   Deafness, autosomal dominant Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03030 DNA replication     4171 (MCM2)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     4171 (MCM2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     4171 (MCM2)    03036 Chromosome and associated proteins [BR:hsa03036]     4171 (MCM2) Enzymes [BR:hsa01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      4171 (MCM2) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    pre-RC (pre-replication complex)     4171 (MCM2) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Other centrosome associated proteins     4171 (MCM2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MCM MCM_OB WH_MCM2 MCM_lid MCM_N MCM2_N Mg_chelatase AAA_3 AAA_5 AAA_lid_2 AAA DUF445 Sigma54_activ_2 Motif Other DBs NCBI-GeneID:  4171 NCBI-ProteinID:  NP_004517 OMIM:  116945 HGNC:  6944 Ensembl:  ENSG00000073111 UniProt:  P49736 Structure PDBPDBj LinkDB All DBs Position 3:127598411..127622436 Genome browser AA seq 904 aa AA seqDB search MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTE GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQR DREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGH SVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAR EHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQL HLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGP FEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHN NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFAS IAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVS SRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDIL CVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVL KKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARI HLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLV AEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMI LQQF NT seq 2715 nt NT seq  +upstreamnt  +downstreamnt atggcggaatcatcggaatccttcaccatggcatccagcccggcccagcgtcggcgaggc aatgatcctctcacctccagccctggccgaagctcccggcgtactgatgccctcacctcc agccctggccgtgaccttccaccatttgaggatgagtccgaggggctcctaggcacagag gggcccctggaggaagaagaggatggagaggagctcattggagatggcatggaaagggac taccgcgccatcccagagctggacgcctatgaggccgagggactggctctggatgatgag gacgtagaggagctgacggccagtcagagggaggcagcagagcgggccatgcggcagcgt gaccgggaggctggccggggcctgggccgcatgcgccgtgggctcctgtatgacagcgat gaggaggacgaggagcgccctgcccgcaagcgccgccaggtggagcgggccacggaggac ggcgaggaggacgaggagatgatcgagagcatcgagaacctggaggatctcaaaggccac tctgtgcgcgagtgggtgagcatggcgggcccccggctggagatccaccaccgcttcaag aacttcctgcgcactcacgtcgacagccacggccacaacgtcttcaaggagcgcatcagc gacatgtgcaaagagaaccgtgagagcctggtggtgaactatgaggacttggcagccagg gagcacgtgctggcctacttcctgcctgaggcaccggcggagctgctgcagatctttgat gaggctgccctggaggtggtactggccatgtaccccaagtacgaccgcatcaccaaccac atccatgtccgcatctcccacctgcctctggtggaggagctgcgctcgctgaggcagctg catctgaaccagctgatccgcaccagtggggtggtgaccagctgcactggcgtcctgccc cagctcagcatggtcaagtacaactgcaacaagtgcaatttcgtcctgggtcctttctgc cagtcccagaaccaggaggtgaaaccaggctcctgtcctgagtgccagtcggccggcccc tttgaggtcaacatggaggagaccatctatcagaactaccagcgtatccgaatccaggag agtccaggcaaagtggcggctggccggctgccccgctccaaggacgccattctcctcgca gatctggtggacagctgcaagccaggagacgagatagagctgactggcatctatcacaac aactatgatggctccctcaacactgccaatggcttccctgtctttgccactgtcatccta gccaaccacgtggccaagaaggacaacaaggttgctgtaggggaactgaccgatgaagat gtgaagatgatcactagcctctccaaggatcagcagatcggagagaagatctttgccagc attgctccttccatctatggtcatgaagacatcaagagaggcctggctctggccctgttc ggaggggagcccaaaaacccaggtggcaagcacaaggtacgtggtgatatcaacgtgctc ttgtgcggagaccctggcacagcgaagtcgcagtttctcaagtatattgagaaagtgtcc agccgagccatcttcaccactggccagggggcgtcggctgtgggcctcacggcgtatgtc cagcggcaccctgtcagcagggagtggaccttggaggctggggccctggttctggctgac cgaggagtgtgtctcattgatgaatttgacaagatgaatgaccaggacagaaccagcatc catgaggccatggagcaacagagcatctccatctcgaaggctggcatcgtcacctccctg caggctcgctgcacggtcattgctgccgccaaccccataggagggcgctacgacccctcg ctgactttctctgagaacgtggacctcacagagcccatcatctcacgctttgacatcctg tgtgtggtgagggacaccgtggacccagtccaggacgagatgctggcccgcttcgtggtg ggcagccacgtcagacaccaccccagcaacaaggaggaggaggggctggccaatggcagc gctgctgagcccgccatgcccaacacgtatggcgtggagcccctgccccaggaggtcctg aagaagtacatcatctacgccaaggagagggtccacccgaagctcaaccagatggaccag gacaaggtggccaagatgtacagtgacctgaggaaagaatctatggcgacaggcagcatc cccattacggtgcggcacatcgagtccatgatccgcatggcggaggcccacgcgcgcatc catctgcgggactatgtgatcgaagacgacgtcaacatggccatccgcgtgatgctggag agcttcatagacacacagaagttcagcgtcatgcgcagcatgcgcaagacttttgcccgc tacctttcattccggcgtgacaacaatgagctgttgctcttcatactgaagcagttagtg gcagagcaggtgacatatcagcgcaaccgctttggggcccagcaggacactattgaggtc cctgagaaggacttggtggataaggctcgtcagatcaacatccacaacctctctgcattt tatgacagtgagctcttcaggatgaacaagttcagccacgacctgaaaaggaaaatgatc ctgcagcagttctga

Homo sapiens (human): 4172 Help Entry 4172              CDS       T01001                                  Symbol MCM3, HCC5, P1-MCM3, P1.h, RLFB Name (RefSeq) minichromosome maintenance complex component 3   KO K02541   DNA replication licensing factor MCM3 [EC:5.6.2.3] Organism hsa  Homo sapiens (human) Pathway hsa03030   DNA replication hsa04110   Cell cycle Network nt06506  Double-strand break repair nt06509  DNA replication   Element N01450   Break induced replication N01468   DNA replication licensing N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03030 DNA replication     4172 (MCM3)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     4172 (MCM3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     4172 (MCM3)    03036 Chromosome and associated proteins [BR:hsa03036]     4172 (MCM3) Enzymes [BR:hsa01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      4172 (MCM3) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    pre-RC (pre-replication complex)     4172 (MCM3) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Other centrosome associated proteins     4172 (MCM3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MCM MCM_OB MCM_lid WH_MCM3_C MCM_N Mg_chelatase MCM4_WHD AAA_3 AAA_5 Sigma54_activat Motif Other DBs NCBI-GeneID:  4172 NCBI-ProteinID:  NP_002379 OMIM:  602693 HGNC:  6945 Ensembl:  ENSG00000112118 UniProt:  P25205 A0A0S2Z4T1 Structure PDBPDBj LinkDB All DBs Position 6:complement(52264015..52284742) Genome browser AA seq 808 aa AA seqDB search MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEK RANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCF LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT YRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLA KSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLC TAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRT AIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFD LLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQ DTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQ DSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEK EKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQV HTPKTADSQETKESQKVELSESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPF SSVEIQAALSKMQDDNQVMVSEGIIFLI NT seq 2427 nt NT seq  +upstreamnt  +downstreamnt atggcgggtaccgtggtgctggacgatgtggagctgcgggaggctcagagagattacctg gacttcctggacgacgaggaagaccagggaatttatcagagcaaagttcgggagctgatc agtgacaaccaataccggctgattgtcaatgtgaatgacctgcgcaggaaaaacgagaag agggctaaccggcttctgaacaatgcctttgaggagctggttgccttccagcgggcctta aaggattttgtggcctccattgatgctacctatgccaagcagtatgaggagttctacgta ggactggaaggcagctttggctccaagcacgtctccccgcggactcttacctcctgcttc ctcagctgtgtggtctgtgtggagggcattgtcactaaatgttctctagttcgtcccaaa gtcgtccgcagtgtccactactgtcctgctactaagaagaccatagagcgacgttattct gatctcaccaccctggtggcctttccctccagctctgtctatcctaccaaggatgaggag aacaatccccttgagacagaatatggcctttctgtctacaaggatcaccagaccatcacc atccaggagatgccggagaaggccccagccggccagctcccccgctctgtggacgtcatt ctggatgatgacttggtggataaagcgaagcctggtgaccgggttcaggtggtgggaacc taccgttgccttcctggaaagaagggaggctacacctctgggaccttcaggactgtcctg attgcctgtaatgttaagcagatgagcaaggatgctcagccctctttctctgctgaggat atagccaagatcaagaagttcagtaaaacccgatccaaggatatctttgaccagctggcc aagtcattggccccaagtatccatgggcatgactatgtcaagaaagcaatcctctgcttg ctcttgggaggggtggaacgagacctagaaaatggcagccacatccgtggggacatcaat attcttctaataggagacccatccgttgccaagtctcagcttctgcggtatgtgctttgc actgcaccccgagctatccccaccactggccggggctcctctggagtgggtctgacggct gctgtcaccacagaccaggaaacaggagagcgccgtctggaagcaggggccatggtcctg gctgaccgaggcgtggtttgcattgatgaatttgacaaaatgtctgacatggatcgcaca gccatccatgaagtgatggagcagggtcgagtgaccattgccaaggctggcatccatgct cggctgaatgcccgctgcagtgttttggcagctgccaaccctgtctacggcaggtatgac cagtataagactccaatggagaacattgggctacaggactcactgctgtcacgatttgac ttgctcttcatcatgctggatcagatggatcctgagcaggatcgggagatctcagaccat gtccttcggatgcaccgttacagagcacctggggagcaggatggcgatgctatgcccttg ggtagtgctgtggatatcctggccacagatgatcccaactttagccaggaagatcagcag gacacccagatttatgagaagcatgacaaccttctacatgggaccaagaagaaaaaggag aagatggtgagtgcagcattcatgaagaagtacatccatgtggccaaaatcatcaagcct gtcctgacacaggagtcggccacctacattgcagaagagtattcacgcctgcgcagccag gatagcatgagctcagacaccgccaggacatctccagttacagcccgaacactggaaact ctgattcgactggccacagcccatgcgaaggcccgcatgagcaagactgtggacctgcag gatgcagaggaagctgtggagttggtccagtatgcttactttaagaaggttctggagaag gagaagaaacgtaagaagcgaagtgaggatgaatcagagacagaagatgaagaggagaaa agccaagaggaccaggagcagaagaggaagagaaggaagactcgccagccagatgccaaa gatggggattcatacgacccctatgacttcagtgacacagaggaggaaatgcctcaagta cacactccaaagacggcagactcacaggagaccaaggaatcccagaaagtggagttgagt gaatccaggttgaaggcattcaaggtggccctcttggatgtgttccgggaagctcatgcg cagtcaatcggcatgaatcgcctcacagaatccatcaaccgggacagcgaagagcccttc tcttcagttgagatccaggctgctctgagcaagatgcaggatgacaatcaggtcatggtg tctgagggcatcatcttcctcatctga

Homo sapiens (human): 4173 Help Entry 4173              CDS       T01001                                  Symbol MCM4, CDC21, CDC54, IMD54, NKCD, NKGCD, P1-CDC21, hCdc21 Name (RefSeq) minichromosome maintenance complex component 4   KO K02212   DNA replication licensing factor MCM4 [EC:5.6.2.3] Organism hsa  Homo sapiens (human) Pathway hsa03030   DNA replication hsa04110   Cell cycle Network nt06506  Double-strand break repair nt06509  DNA replication   Element N01450   Break induced replication N01468   DNA replication licensing N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Disease H00094   Immunodeficiency associated with DNA repair defects Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03030 DNA replication     4173 (MCM4)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     4173 (MCM4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     4173 (MCM4) Enzymes [BR:hsa01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      4173 (MCM4) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    pre-RC (pre-replication complex)     4173 (MCM4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MCM MCM_OB MCM_lid MCM_N MCM4_WHD Mg_chelatase AAA_5 AAA_3 AAA GMT-wHTH Zn_ribbon_Elf1 Motif Other DBs NCBI-GeneID:  4173 NCBI-ProteinID:  NP_005905 OMIM:  602638 HGNC:  6947 Ensembl:  ENSG00000104738 UniProt:  P33991 B4DLA6 Structure PDBPDBj LinkDB All DBs Position 8:47960941..47978160 Genome browser AA seq 863 aa AA seqDB search MSSPASTPSRRGSRRGRATPAQTPRSEDARSSPSQRRRGEDSTSTGELQPMPTSPGVDLQ SPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRPDLGS AQKGLQVDLQSDGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKE EENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMA VNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQ EAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPED MPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIH YRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGI LLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAK AGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDR RLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKI GSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGI VDISILTTGMSATSRKRKEELAEALKKLILSKGKTPALKYQQLFEDIRGQSDIAITKDMF EEALRALADDDFLTVTGKTVRLL NT seq 2592 nt NT seq  +upstreamnt  +downstreamnt atgtcgtccccggcgtcgaccccgagccgccgcggcagccggcgtggaagggccaccccc gcccagacgcctcggagtgaggatgccaggtcatctccctctcagagacgtagaggcgag gattccacctccacgggggagttgcagccgatgccaacctcgcctggagtggacctgcag agccctgctgcgcaggacgtgctgttttccagccctccccaaatgcattcttcagctatc cctcttgactttgatgttagttcaccactgacatacggcactcccagctctcgggtagag ggaaccccaagaagtggtgttaggggcacacctgtgagacagaggcctgacctgggctct gcacagaagggcctgcaagtggatctgcagtctgacggggcagcagcagaagatatagtg gcaagtgagcagtctctaggccaaaaacttgtgatctggggaacagatgtaaatgtggca gcatgcaaagaaaactttcagagatttcttcagcgttttattgaccctctggctaaagaa gaagaaaatgttggcatagatattactgaacctctatacatgcaacgacttggggagatt aatgttattggtgagccatttttaaatgtgaactgtgaacacatcaaatcatttgacaaa aatttgtacagacaactcatctcttacccacaggaagttattccaacttttgacatggct gtcaatgaaatcttctttgaccgttaccctgactcaatcttagaacatcagattcaagta agaccattcaacgcattgaagactaagaatatgagaaacctgaatccagaagacattgac cagctcatcaccatcagcggcatggtgatcaggacatcccagctgattcccgagatgcag gaggccttcttccagtgccaagtgtgtgcccacacgacccgggtggagatggaccgcggc cgcattgcagagcccagtgtgtgcgggcgctgccacaccacccacagcatggcactcatc cacaaccgctccctcttctctgacaagcagatgatcaagcttcaggagtctccggaagac atgcctgcagggcagacaccacacacagttatcctgtttgctcacaatgatctcgttgac aaggtccagcctggggacagagtgaatgttacaggcatctatcgagctgtgcctattcga gtcaatccaagagtgagtaatgtgaagtctgtctacaaaacccacattgatgtcattcat tatcggaaaacggatgcaaaacgtctgcatggccttgatgaagaagcagaacagaaactt ttttcagagaaacgtgtggaattgcttaaggaactttccaggaaaccagacatttatgag aggcttgcttcagccttggctccaagcatttatgaacatgaagatataaagaagggaatt ttgcttcagctctttggcgggacaaggaaggattttagtcacactggaaggggcaaattt cgggctgagatcaacatcttgctgtgtggcgaccctggtaccagcaagtcccagctgctg cagtacgtgtacaacctcgtccccaggggccagtacacgtctgggaagggctccagtgca gttggcctcactgcgtacgtaatgaaagaccctgagacaaggcagctggtcctgcagaca ggtgctcttgtcctgagtgacaacggcatctgctgtatcgatgagttcgacaagatgaat gaaagtacaagatcggtattgcatgaagtcatggaacagcagactctgtccattgcaaag gctgggatcatctgtcagctcaatgcgcgcacctctgtcctggcagcagcaaatcccatt gagtctcagtggaatcctaaaaaaacaaccattgaaaacatccagctgcctcatacttta ttatcaaggtttgatttgatcttcctcttgctggaccctcaggacgaagcctatgacagg cgtctggctcaccacctggtcgcactgtactaccagagcgaggagcaggcagaggaggag ctcctggacatggcggtgctaaaggactacattgcctacgcgcacagcaccatcatgccg cggctaagtgaggaagccagccaggctctcatcgaggcttatgtagacatgaggaagatt ggcagtagccggggaatggtttctgcataccctcgacagctagagtcattaatccgctta gcagaagcccatgctaaagtaagattgtctaacaaagttgaagccattgatgtggaagag gccaaacgcctccatcgggaagctctgaagcagtctgcaactgatccccggactggcatc gtggacatatctattcttactacggggatgagtgccacctctcgtaaacggaaagaagaa ttagctgaagcattgaaaaagcttattttatctaagggcaaaacaccagctctaaaatac cagcaactttttgaagatattcggggacaatctgacatagcaattactaaagatatgttt gaagaagcactgcgtgccctggcagatgatgatttcctgacagtgactgggaagaccgtg cgcttgctctga

Homo sapiens (human): 4174 Help Entry 4174              CDS       T01001                                  Symbol MCM5, CDC46, MGORS8, P1-CDC46 Name (RefSeq) minichromosome maintenance complex component 5   KO K02209   DNA replication licensing factor MCM5 [EC:5.6.2.3] Organism hsa  Homo sapiens (human) Pathway hsa03030   DNA replication hsa04110   Cell cycle Network nt06506  Double-strand break repair nt06509  DNA replication   Element N01450   Break induced replication N01468   DNA replication licensing N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Disease H01889   Meier-Gorlin syndrome Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03030 DNA replication     4174 (MCM5)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     4174 (MCM5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     4174 (MCM5)    03036 Chromosome and associated proteins [BR:hsa03036]     4174 (MCM5) Enzymes [BR:hsa01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      4174 (MCM5) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    pre-RC (pre-replication complex)     4174 (MCM5) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centrosome duplication proteins     Other centrosome duplication proteins      4174 (MCM5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MCM MCM_OB MCM_lid MCM5_C MCM_N Mg_chelatase AAA_5 AAA_3 Sigma54_activat Motif Other DBs NCBI-GeneID:  4174 NCBI-ProteinID:  NP_006730 OMIM:  602696 HGNC:  6948 Ensembl:  ENSG00000100297 UniProt:  P33992 B1AHB0 Structure PDBPDBj LinkDB All DBs Position 22:35400140..35455031 Genome browser AA seq 734 aa AA seqDB search MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH VSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDS DRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGV EGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGE IQHRMQRKVLYRLK NT seq 2205 nt NT seq  +upstreamnt  +downstreamnt atgtcgggattcgacgatcctggcattttctacagcgacagcttcgggggcgacgcccag gccgacgaggggcaggcccgcaaatcgcagctgcagaggcgcttcaaggagttcctgcgg cagtaccgagtgggcaccgaccgcacgggcttcaccttcaaatacagggatgaactcaag cggcattacaacctgggggagtactggattgaggtggagatggaggatctggccagcttt gatgaggacctggccgactacttgtacaagcagccagccgagcacctgcagctgctggag gaagctgccaaggaggtagctgatgaggtgacccggccccggccttctggggaggaggtg ctccaggacatccaggtcatgctcaagtcggacgccagcccttccagcattcgtagcctg aagtcggacatgatgtcacacctggtgaagatccctggcatcatcatcgcggcctctgcg gtccgtgccaaggccacccgcatctctatccagtgccgcagctgccgcaacaccctcacc aacattgccatgcgccctggcctcgagggctatgccctgcccaggaagtgcaacacagat caggctgggcgccccaaatgcccattggacccgtacttcatcatgcccgacaaatgcaaa tgcgtggacttccagaccctgaagctgcaggagctgcctgatgcagtcccccacggggag atgcccagacacatgcagctctactgcgacaggtacctgtgtgacaaggtcgtccctggg aacagggttaccatcatgggcatctactccatcaagaagtttggcctgactaccagcagg ggccgtgacagggtgggcgtgggcatccgaagctcctacatccgtgtcctgggcatccag gtggacacagatggctctggccgcagctttgctggggccgtgagcccccaggaggaggag gagttccgtcgcctggctgccctcccaaatgtctatgaggtcatctccaagagcatcgcc ccctccatctttgggggcacagacatgaagaaggccattgcctgcctgctctttgggggc tcccgaaagaggctccctgatggacttactcgccgaggagacatcaacctgctgatgcta ggggaccctgggacagccaagtcccagcttctgaagtttgtggagaagtgttctcccatt ggggtatacacgtctgggaaaggcagcagcgcagctggactgacagcctcggtgatgagg gacccttcgtcccggaatttcatcatggagggcggagccatggtcctggccgatggtggg gtcgtctgtattgacgagtttgacaagatgcgagaagatgaccgtgtggcaatccacgaa gccatggagcagcagaccatctctatcgccaaggctgggatcaccaccaccctgaactcc cgctgctccgtcctggctgctgccaactcagtgttcggccgctgggatgagacgaagggg gaggacaacattgacttcatgcccaccatcttgtcgcgcttcgacatgatcttcatcgtc aaggatgagcacaatgaggagagggatgtgatgctggccaagcatgtcatcactctgcac gtgagcgcactgacacagacacaggctgtggagggcgagattgacctggccaagctgaag aagtttattgcctactgccgagtgaagtgtggcccccggctgtcagcagaggctgcagag aaactgaagaaccgctacatcatcatgcggagcggggcccgtcagcacgagagggacagt gaccgccgctccagcatccccatcactgtgcggcagctggaggccattgtgcgcatcgcg gaagccctcagcaagatgaagctgcagcccttcgccacagaggcagatgtggaggaggcc ctgcggctcttccaagtgtccacgttggatgctgccttgtccggtaccctgtcaggggtg gagggcttcaccagccaggaggaccaggagatgctgagccgcatcgagaagcagctcaag cgccgctttgccattggctcccaggtgtctgagcacagcatcatcaaggacttcaccaag cagaaatacccggagcacgccatccacaaggtgctgcagctcatgctgcggcgcggcgag atccagcatcgcatgcagcgcaaggttctctaccgcctcaagtga

Homo sapiens (human): 4175 Help Entry 4175              CDS       T01001                                  Symbol MCM6, MCG40308, Mis5, P105MCM Name (RefSeq) minichromosome maintenance complex component 6   KO K02542   DNA replication licensing factor MCM6 [EC:5.6.2.3] Organism hsa  Homo sapiens (human) Pathway hsa03030   DNA replication hsa04110   Cell cycle Network nt06506  Double-strand break repair nt06509  DNA replication   Element N01450   Break induced replication N01468   DNA replication licensing N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Disease H02575   Lactose intolerance, adult type Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09124 Replication and repair    03030 DNA replication     4175 (MCM6)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     4175 (MCM6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     4175 (MCM6) Enzymes [BR:hsa01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      4175 (MCM6) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    pre-RC (pre-replication complex)     4175 (MCM6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MCM MCM_OB MCM6_C MCM_lid MCM_N Mg_chelatase AAA_3 AAA_5 Sigma54_activat Motif Other DBs NCBI-GeneID:  4175 NCBI-ProteinID:  NP_005906 OMIM:  601806 HGNC:  6949 Ensembl:  ENSG00000076003 UniProt:  Q14566 Structure PDBPDBj LinkDB All DBs Position 2:complement(135839626..135876443) Genome browser AA seq 821 aa AA seqDB search MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNT LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR HKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD KCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLA CCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHG NDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTS GKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQ TISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDEC NEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKH LRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVE TPDVNLDQEEEIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEY CRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRL THYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLED NT seq 2466 nt NT seq  +upstreamnt  +downstreamnt atggacctcgcggcggcagcggagccgggcgccggcagccagcacctggaggtccgcgac gaggtggccgagaagtgccagaaactgttcctggacttcttggaggagtttcagagcagc gatggagaaattaaatacttgcaattagcagaggaactgattcgtcctgagagaaacaca ttggttgtgagttttgtggacctggaacaatttaaccagcaactttccaccaccattcaa gaggagttctatagagtttacccttacctgtgtcgggccttgaaaacattcgtcaaagac cgtaaagagatccctcttgccaaggatttttatgttgcattccaagacctgcctaccaga cacaagattcgagagctcacctcatccagaattggtttgctcactcgcatcagtgggcag gtggtgcggactcacccagttcacccagagcttgtgagcggaacttttctgtgcttggac tgtcagacagtgatcagggatgtagaacagcagttcaaatacacacagccaaacatctgc cgaaatccagtttgtgccaacaggaggagattcttactggatacaaataaatcaagattt gttgattttcaaaaggttcgtattcaagagacccaagctgagcttcctcgagggagtatc ccccgcagtttagaagtaattttaagggctgaagctgtggaatcagctcaagctggtgac aagtgtgactttacagggacactgattgttgtgcctgacgtctccaagcttagcacacca ggagcacgtgcagaaactaattcccgtgtcagtggtgttgatggatatgagacagaaggc attcgaggactccgggcccttggtgttagggacctttcttataggctggtctttcttgcc tgctgtgttgcgccaaccaacccaaggtttggggggaaagagctcagagatgaggaacag acagctgagagcattaagaaccaaatgactgtgaaagaatgggagaaagtgtttgagatg agtcaagataaaaatctataccacaatctttgtaccagcctgttccctactatacatggc aatgatgaagtaaaacggggtgtcctgctgatgctctttggtggcgttccaaagacaaca ggagaagggacctctcttcgaggggacataaatgtttgcattgttggtgacccaagtaca gctaagagccaatttctcaagcacgtggaggagttcagccccagagctgtctacaccagt ggtaaagcgtccagtgctgctggcttaacagcagctgttgtgagagatgaagaatctcat gagtttgtcattgaggctggagctttgatgttggctgataatggtgtgtgttgtattgat gaatttgataagatggacgtgcgggatcaagttgctattcatgaagctatggaacagcag accatatccatcactaaagcaggagtgaaggctactctgaacgcccggacgtccattttg gcagcagcaaacccaatcagtggacactatgacagatcaaaatcattgaaacagaatata aatttgtcagctcccatcatgtcccgattcgatctcttctttatccttgtggatgaatgt aatgaggttacagattatgccattgccaggcgcatagtagatttgcattcaagaattgag gaatcaattgatcgtgtctattccctcgatgatatcagaagatatcttctctttgcaaga cagtttaaacccaagatttccaaagagtcagaggacttcattgtggagcaatataaacat ctccgccagagagatggttctggagtgaccaagtcttcatggaggattacagtgcgacag cttgagagcatgattcgtctctctgaagctatggctcggatgcactgctgtgatgaggtc caacctaaacatgtgaaggaagctttccggttactgaataaatcaatcatccgtgtggaa acacctgatgtcaatctagatcaagaggaagagatccagatggaggtagatgagggtgct ggtggcatcaatggtcatgctgacagccctgctcctgtgaacgggatcaatggctacaat gaagacataaatcaagagtctgctcccaaagcctccttaaggctgggcttctctgagtac tgccgaatctctaaccttattgtgcttcacctcagaaaggtggaagaagaagaggacgag tcagcattaaagaggagcgagcttgttaactggtacttgaaggaaatcgaatcagagata gactctgaagaagaacttataaataaaaaaagaatcatagagaaagttattcatcgactc acacactatgatcatgttctaattgagctcacccaggctggattgaaaggctccacagag ggaagtgagagctatgaagaagatccctacttggtagttaaccctaactacttgctcgaa gattga

Homo sapiens (human): 9837 Help Entry 9837              CDS       T01001                                  Symbol GINS1, IMD55, PSF1 Name (RefSeq) GINS complex subunit 1   KO K10732   GINS complex subunit 1 Organism hsa  Homo sapiens (human) Network nt06509  DNA replication   Element N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Disease H00093   Combined immunodeficiency Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     9837 (GINS1) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    GINS complex     9837 (GINS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PSF1_C Sld5 Motif Other DBs NCBI-GeneID:  9837 NCBI-ProteinID:  NP_066545 OMIM:  610608 HGNC:  28980 Ensembl:  ENSG00000101003 UniProt:  Q14691 Structure PDBPDBj LinkDB All DBs Position 20:25407673..25448563 Genome browser AA seq 196 aa AA seqDB search MFCEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSGGRSDLIP TIKFRHCSLLRNRRCTVAYLYDRLLRIRALRWEYGSVLPNALRFHMAAEEMEWFNNYKRS LATYMRSLGGDEGLDITQDMKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRW KCEQLIRQGVLEHILS NT seq 591 nt NT seq  +upstreamnt  +downstreamnt atgttctgcgaaaaagccatggaactgatccgcgagctgcatcgcgcgcccgaagggcaa ctgcctgccttcaacgaggatggactcagacaagttctggaggagatgaaagctttgtat gaacaaaaccagtctgatgtgaatgaagcaaagtcaggtggacgaagtgatttgatacca actatcaaatttcgacactgttctctgttaagaaatcgacgctgcactgtagcatacctg tatgaccgcttgcttcggatcagagcactcagatgggaatatggtagcgtcttgccaaat gcattacgatttcacatggctgctgaagaaatggagtggtttaataattataaaagatct cttgctacttatatgaggtcactgggaggagatgaaggtttggacattacacaggatatg aaaccaccaaaaagcctatatattgaagtccggtgtctaaaagactatggagaatttgaa gttgatgatggcacttcagtcctattaaaaaaaaatagccagcactttttacctcgatgg aaatgtgagcagctgatcagacaaggagtcctggagcacatcctgtcatga

Homo sapiens (human): 51659 Help Entry 51659             CDS       T01001                                  Symbol GINS2, HSPC037, PSF2, Pfs2 Name (RefSeq) GINS complex subunit 2   KO K10733   GINS complex subunit 2 Organism hsa  Homo sapiens (human) Network nt06509  DNA replication   Element N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     51659 (GINS2) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    GINS complex     51659 (GINS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PSF2_N Sld5 Motif Other DBs NCBI-GeneID:  51659 NCBI-ProteinID:  NP_057179 OMIM:  610609 HGNC:  24575 Ensembl:  ENSG00000131153 UniProt:  Q9Y248 Structure PDBPDBj LinkDB All DBs Position 16:complement(85676198..85688954) Genome browser AA seq 185 aa AA seqDB search MDAAEVEFLAEKELVTIIPNFSLDKIYLIGGDLGPFNPGLPVEVPLWLAINLKQRQKCRL LPPEWMDVEKLEKMRDHERKEETFTPMPSPYYMELTKLLLNHASDNIPKADEIRTLVKDM WDTRIAKLRVSADSFVRQQEAHAKLDNLTLMEINTSGTFLTQALNHMYKLRTNLQPLEST QSQDF NT seq 558 nt NT seq  +upstreamnt  +downstreamnt atggacgctgccgaggtcgaattcctcgccgagaaggagctggttaccattatccccaac ttcagtctggacaagatctacctcatcgggggggacctggggccttttaaccctggttta cccgtggaagtgcccctgtggctggcgattaacctgaaacaaagacagaaatgtcgcctg ctccctccagagtggatggatgtagaaaagttggagaagatgagggatcatgaacgaaag gaagaaacttttaccccaatgcccagcccttactacatggaacttacgaagctcctgtta aatcatgcttcagacaacatcccgaaggcagacgaaatccggaccctggtcaaggatatg tgggacactcgtatagccaaactccgagtgtctgctgacagctttgtgagacagcaggag gcacatgccaagctggataacttgaccttgatggagatcaacaccagcgggactttcctc acacaagcgctcaaccacatgtacaaactccgcacgaacctccagcctctggagagtact cagtctcaggacttctag

Homo sapiens (human): 64785 Help Entry 64785             CDS       T01001                                  Symbol GINS3, PSF3 Name (RefSeq) GINS complex subunit 3   KO K10734   GINS complex subunit 3 Organism hsa  Homo sapiens (human) Network nt06509  DNA replication   Element N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     64785 (GINS3) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    GINS complex     64785 (GINS3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PSF3_N Sld5 Motif Other DBs NCBI-GeneID:  64785 NCBI-ProteinID:  NP_073607 OMIM:  610610 HGNC:  25851 Ensembl:  ENSG00000181938 UniProt:  Q9BRX5 A0A0S2Z5L0 Structure PDBPDBj LinkDB All DBs Position 16:58392471..58406147 Genome browser AA seq 216 aa AA seqDB search MSEAYFRVESGALGPEENFLSLDDILMSHEKLPVRTETAMPRLGAFFLERSAGAETDNAV PQGSKLELPLWLAKGLFDNKRRILSVELPKIYQEGWRTVFSADPNVVDLHKMGPHFYGFG SQLLHFDSPENADISQSLLQTFIGRFRRIMDSSQNAYNEDTSALVARLDEMERGLFQTGQ KGLNDFQCWEKGQASQITASNLVQNYKKRKFTDMED NT seq 651 nt NT seq  +upstreamnt  +downstreamnt atgtcagaggcttatttccgagtggagtcgggtgcgctggggcctgaggagaactttctt tctttggacgacatcctgatgtcccacgagaagctgccggtgcgcacggagaccgccatg cctcgccttggcgctttcttcctggagcggagcgcaggcgccgagactgacaacgcggtc ccacagggttccaagcttgaactacccttgtggctggcaaaaggactttttgacaacaag cgacggatcctttctgtggaactccccaagatctaccaagagggttggaggactgtgttc agtgcagatcccaatgtggtggacctccacaaaatggggccccatttctacgggtttggc tcccagctcctgcattttgacagtcccgagaatgcagacatttcccagtctctgctgcag acttttatcggacgttttcgccgcatcatggactcctcacagaatgcttacaacgaagac acttcagccctggtagccaggctagacgagatggagaggggcttatttcaaacagggcag aaaggactgaatgactttcagtgttgggagaaggggcaggcttctcagatcacagcttcc aacctcgttcagaattacaagaagagaaaattcactgatatggaagactga

Homo sapiens (human): 84296 Help Entry 84296             CDS       T01001                                  Symbol GINS4, SLD5 Name (RefSeq) GINS complex subunit 4   KO K10735   GINS complex subunit 4 Organism hsa  Homo sapiens (human) Network nt06509  DNA replication   Element N01470   Pre-IC formation N01471   Origin unwinding and elongation N01473   DNA replication termination N01474   TRAIP-dependent replisome disassembly Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     84296 (GINS4) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    GINS complex     84296 (GINS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  SLD5_C Sld5 Motif Other DBs NCBI-GeneID:  84296 NCBI-ProteinID:  NP_115712 OMIM:  610611 HGNC:  28226 Ensembl:  ENSG00000147536 UniProt:  Q9BRT9 Structure PDBPDBj LinkDB All DBs Position 8:41529261..41545030 Genome browser AA seq 223 aa AA seqDB search MTEEVDFLGQDSDGGSEEVVLTPAELIERLEQAWMNEKFAPELLESKPEIVECVMEQLEH MEENLRRAKREDLKVSIHQMEMERIRYVLSSYLRCRLMKIEKFFPHVLEKEKTRPEGEPS SLSPEELAFAREFMANTESYLKNVALKHMPPNLQKVDLFRAVPKPDLDSYVFLRVRERQE NILVEPDTDEQRDYVIDLEKGSQHLIRYKTIAPLVASGAVQLI NT seq 672 nt NT seq  +upstreamnt  +downstreamnt atgaccgaagaagtggatttcctgggacaggactctgatgggggtagtgaggaagtggtc ctaactcctgcagagctcattgaaagattggagcaggcctggatgaatgaaaagtttgcc cctgagctgctggagagcaagcctgagattgtagaatgtgtcatggaacagctggagcac atggaagaaaatctcaggagagccaaaagggaggacctgaaggtcagcatccaccaaatg gagatggagaggatccgctacgtcctcagcagctacttgcggtgtcgcctcatgaagata gagaagtttttccctcatgtccttgagaaggaaaaaacacgtcctgagggggagccttcc agcctctcgccggaagagttggcctttgccagagagttcatggcgaacacagagtcctat ctgaaaaatgtcgccttgaagcacatgccccctaacttacagaaggtggacctctttcgg gcagttcccaaaccagatctagattcttacgtgtttctgagagtgagagaacgacaagaa aacatactggtagaaccagacacagatgagcagagggactacgtgattgacctggagaag ggctcacagcacttgatccgatacaaaaccattgcacctctggttgcatctggagctgtc cagctaatttaa

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