KEGG   PATHWAY: mmu00430
Entry
mmu00430                    Pathway                                
Name
Taurine and hypotaurine metabolism - Mus musculus (house mouse)
Class
Metabolism; Metabolism of other amino acids
Pathway map
mmu00430  Taurine and hypotaurine metabolism
mmu00430

Other DBs
GO: 0019530
Organism
Mus musculus (house mouse) [GN:mmu]
Gene
12012  Baat; bile acid-Coenzyme A: amino acid N-acyltransferase [KO:K00659] [EC:2.3.1.65 3.1.2.2]
12583  Cdo1; cysteine dioxygenase 1, cytosolic [KO:K00456] [EC:1.13.11.20]
14261  Fmo1; flavin containing monooxygenase 1 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
14262  Fmo3; flavin containing monooxygenase 3 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
14263  Fmo5; flavin containing monooxygenase 5 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
14415  Gad1; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
14417  Gad2; glutamic acid decarboxylase 2 [KO:K01580] [EC:4.1.1.15]
14598  Ggt1; gamma-glutamyltransferase 1 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
207182  Ggt7; gamma-glutamyltransferase 7 [KO:K00681] [EC:2.3.2.2 3.4.19.13]
209186  Acnat2; acyl-coenzyme A amino acid N-acyltransferase 2 [KO:K00659] [EC:2.3.1.65 3.1.2.2]
211488  Ado; 2-aminoethanethiol dioxygenase [KO:K10712] [EC:1.13.11.19]
226564  Fmo4; flavin containing monooxygenase 4 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
226565  Fmo6; flavin containing monooxygenase 6 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
226601  Gm4846; predicted gene 4846 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
226604  Gm4847; predicted gene 4847 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
230161  Acnat1; acyl-coenzyme A amino acid N-acyltransferase 1 [KO:K00659] [EC:2.3.1.65 3.1.2.2]
23887  Ggt5; gamma-glutamyltransferase 5 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
240894  Fmo9; flavin containing monooxygenase 9 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
246277  Csad; cysteine sulfinic acid decarboxylase [KO:K18966] [EC:4.1.1.29 4.1.1.11]
55990  Fmo2; flavin containing monooxygenase 2 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
71522  Ggt6; gamma-glutamyltransferase 6 [KO:K00681] [EC:2.3.2.2 3.4.19.13]
73748  Gadl1; glutamate decarboxylase-like 1 [KO:K18966] [EC:4.1.1.29 4.1.1.11]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00033  Acetate
C00041  L-Alanine
C00084  Acetaldehyde
C00094  Sulfite
C00097  L-Cysteine
C00227  Acetyl phosphate
C00245  Taurine
C00506  L-Cysteate
C00519  Hypotaurine
C00593  Sulfoacetaldehyde
C00606  3-Sulfino-L-alanine
C01678  Cysteamine
C01959  Taurocyamine
C03149  N-Phosphotaurocyamine
C05122  Taurocholate
C05123  2-Hydroxyethanesulfonate
C05844  5-L-Glutamyl-taurine
C06735  Aminoacetaldehyde
C14179  Sulfoacetate
C19685  Sulfoacetyl-CoA
Reference
  Authors
Cook AM, Denger K.
  Title
Dissimilation of the C2 sulfonates.
  Journal
Arch Microbiol 179:1-6 (2002)
DOI:10.1007/s00203-002-0497-0
Reference
  Authors
Laue H, Cook AM.
  Title
Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia.
  Journal
Eur J Biochem 267:6841-8 (2000)
DOI:10.1046/j.1432-1033.2000.01782.x
Reference
  Authors
Ruff J, Denger K, Cook AM.
  Title
Sulphoacetaldehyde acetyltransferase yields acetyl phosphate: purification from Alcaligenes defragrans and gene clusters in taurine degradation.
  Journal
Biochem J 369:275-85 (2003)
DOI:10.1042/BJ20021455
Reference
  Authors
Bruggemann C, Denger K, Cook AM, Ruff J.
  Title
Enzymes and genes of taurine and isethionate dissimilation in Paracoccus denitrificans.
  Journal
Microbiology 150:805-16 (2004)
DOI:10.1099/mic.0.26795-0
Reference
  Authors
Denger K, Weinitschke S, Hollemeyer K, Cook AM.
  Title
Sulfoacetate generated by Rhodopseudomonas palustris from taurine.
  Journal
Arch Microbiol 182:254-8 (2004)
DOI:10.1007/s00203-004-0678-0
Reference
  Authors
Denger K, Ruff J, Schleheck D, Cook AM.
  Title
Rhodococcus opacus expresses the xsc gene to utilize taurine as a carbon source or as a nitrogen source but not as a sulfur source.
  Journal
Microbiology 150:1859-67 (2004)
DOI:10.1099/mic.0.27077-0
Reference
  Authors
Styp von Rekowski K, Denger K, Cook AM.
  Title
Isethionate as a product from taurine during nitrogen-limited growth of Klebsiella oxytoca TauN1.
  Journal
Arch Microbiol 183:325-30 (2005)
DOI:10.1007/s00203-005-0776-7
Reference
PMID:4297098
  Authors
Jacobsen JG, Smith LH
  Title
Biochemistry and physiology of taurine and taurine derivatives.
  Journal
Physiol Rev 48:424-511 (1968)
DOI:10.1152/physrev.1968.48.2.424
Related
pathway
mmu00270  Cysteine and methionine metabolism
mmu00480  Glutathione metabolism
mmu00620  Pyruvate metabolism
mmu00920  Sulfur metabolism
KO pathway
ko00430   

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