KEGG   PATHWAY: mmu00561
Entry
mmu00561                    Pathway                                
Name
Glycerolipid metabolism - Mus musculus (house mouse)
Class
Metabolism; Lipid metabolism
Pathway map
mmu00561  Glycerolipid metabolism
mmu00561

Module
mmu_M00089  Triacylglycerol biosynthesis [PATH:mmu00561]
mmu_M00098  Acylglycerol degradation [PATH:mmu00561]
Other DBs
GO: 0046486
Organism
Mus musculus (house mouse) [GN:mmu]
Gene
235582  Glyctk; glycerate kinase [KO:K11529] [EC:2.7.1.165]
11669  Aldh2; aldehyde dehydrogenase 2, mitochondrial [KO:K00128] [EC:1.2.1.3]
11671  Aldh3a2; aldehyde dehydrogenase family 3, subfamily A2 [KO:K00128] [EC:1.2.1.3]
72535  Aldh1b1; aldehyde dehydrogenase 1 family, member B1 [KO:K00128] [EC:1.2.1.3]
110695  Aldh7a1; aldehyde dehydrogenase family 7, member A1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
56752  Aldh9a1; aldehyde dehydrogenase 9, subfamily A1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
11997  Akr1b7; aldo-keto reductase family 1, member B7 [KO:K00011] [EC:1.1.1.21]
14187  Akr1b8; aldo-keto reductase family 1, member B8 [KO:K00011] [EC:1.1.1.21]
11677  Akr1b1; aldo-keto reductase family 1 member B [KO:K00011] [EC:1.1.1.21]
67861  Akr1b10; aldo-keto reductase family 1, member B10 [KO:K00011] [EC:1.1.1.21]
58810  Akr1a1; aldo-keto reductase family 1, member A1 [KO:K00002] [EC:1.1.1.2]
225913  Tkfc; triokinase, FMN cyclase [KO:K00863] [EC:2.7.1.28 2.7.1.29 4.6.1.15]
14933  Gk; glycerol kinase [KO:K00864] [EC:2.7.1.30]
14626  Gk2; glycerol kinase 2 [KO:K00864] [EC:2.7.1.30]
14625  Gykl1; glycerol kinase-like 1 [KO:K00864] [EC:2.7.1.30]
14732  Gpam; glycerol-3-phosphate acyltransferase, mitochondrial [KO:K00629] [EC:2.3.1.15]
215456  Gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
102247  Gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
231510  Gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
55979  Agpat1; 1-acylglycerol-3-phosphate O-acyltransferase 1 [KO:K13509] [EC:2.3.1.51]
67512  Agpat2; 1-acylglycerol-3-phosphate O-acyltransferase 2 [KO:K13509] [EC:2.3.1.51]
28169  Agpat3; 1-acylglycerol-3-phosphate O-acyltransferase 3 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
68262  Agpat4; 1-acylglycerol-3-phosphate O-acyltransferase 4 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
52123  Agpat5; 1-acylglycerol-3-phosphate O-acyltransferase 5 [KO:K19007] [EC:2.3.1.51]
225010  Lclat1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
218121  Mboat1; membrane bound O-acyltransferase domain containing 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
67216  Mboat2; membrane bound O-acyltransferase domain containing 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
19012  Plpp1; phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
50784  Plpp2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
67916  Plpp3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
14245  Lpin1; lipin 1 [KO:K15728] [EC:3.1.3.4]
64899  Lpin3; lipin 3 [KO:K15728] [EC:3.1.3.4]
64898  Lpin2; lipin 2 [KO:K15728] [EC:3.1.3.4]
71910  Plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
381925  Plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
13139  Dgka; diacylglycerol kinase, alpha [KO:K00901] [EC:2.7.1.107]
110197  Dgkg; diacylglycerol kinase, gamma [KO:K00901] [EC:2.7.1.107]
110524  Dgkq; diacylglycerol kinase, theta [KO:K00901] [EC:2.7.1.107]
104418  Dgkz; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
217480  Dgkb; diacylglycerol kinase, beta [KO:K00901] [EC:2.7.1.107]
56077  Dgke; diacylglycerol kinase, epsilon [KO:K00901] [EC:2.7.1.107]
320127  Dgki; diacylglycerol kinase, iota [KO:K00901] [EC:2.7.1.107]
380921  Dgkh; diacylglycerol kinase, eta [KO:K00901] [EC:2.7.1.107]
227333  Dgkd; diacylglycerol kinase, delta [KO:K00901] [EC:2.7.1.107]
331374  Dgkk; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
13350  Dgat1; diacylglycerol O-acyltransferase 1 [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
67800  Dgat2; diacylglycerol O-acyltransferase 2 [KO:K11160] [EC:2.3.1.20 2.3.1.75]
12613  Cel; carboxyl ester lipase [KO:K12298] [EC:3.1.1.13 3.1.1.3]
66853  Pnpla2; patatin-like phospholipase domain containing 2 [KO:K16816] [EC:3.1.1.3]
116939  Pnpla3; patatin-like phospholipase domain containing 3 [KO:K13534] [EC:3.1.1.3 2.3.1.-]
69060  Pnlip; pancreatic lipase [KO:K14073] [EC:3.1.1.3]
18946  Pnliprp1; pancreatic lipase related protein 1 [KO:K14074] [EC:3.1.1.3]
18947  Pnliprp2; pancreatic lipase-related protein 2 [KO:K14075] [EC:3.1.1.3]
15450  Lipc; lipase, hepatic [KO:K22283] [EC:3.1.1.3]
67717  Lipf; lipase, gastric [KO:K14452] [EC:3.1.1.3]
16891  Lipg; lipase, endothelial [KO:K22284] [EC:3.1.1.3]
16956  Lpl; lipoprotein lipase [KO:K01059] [EC:3.1.1.34]
69923  Agk; acylglycerol kinase [KO:K09881] [EC:2.7.1.94]
23945  Mgll; monoglyceride lipase [KO:K01054] [EC:3.1.1.23]
193742  Abhd16a; abhydrolase domain containing 16A [KO:K25824] [EC:3.1.1.23 3.1.-.-]
68393  Mogat1; monoacylglycerol O-acyltransferase 1 [KO:K14458] [EC:2.3.1.22]
233549  Mogat2; monoacylglycerol O-acyltransferase 2 [KO:K14457] [EC:2.3.1.22]
11605  Gla; galactosidase, alpha [KO:K01189] [EC:3.2.1.22]
Compound
C00029  UDP-glucose
C00040  Acyl-CoA
C00093  sn-Glycerol 3-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00162  Fatty acid
C00173  Acyl-[acyl-carrier protein]
C00184  Glycerone
C00197  3-Phospho-D-glycerate
C00258  D-Glycerate
C00416  Phosphatidate
C00422  Triacylglycerol
C00577  D-Glyceraldehyde
C00631  2-Phospho-D-glycerate
C00641  1,2-Diacyl-sn-glycerol
C00681  1-Acyl-sn-glycerol 3-phosphate
C00969  3-Hydroxypropanal
C01885  1-Acylglycerol
C02133  Acyl phosphate
C02457  Propane-1,3-diol
C03692  1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol
C04046  3-D-Glucosyl-1,2-diacylglycerol
C04315  2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol
C04872  1,2-Diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol
C05401  3-beta-D-Galactosyl-sn-glycerol
C06037  Digalactosyl-diacylglycerol
C06038  Acyl1-monogalactosyl-diacylglycerol
C06040  Diglucosyldiacylglycerol
C06041  Glycerophosphoglycoglycerolipid
C06042  Lipoteichoic acid
C06364  1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol
C06365  alpha-Kojibiosyldiacylglycerol
C11521  UDP-6-sulfoquinovose
C13508  Sulfoquinovosyldiacylglycerol
C20897  Glycerophosphoglycoglycerolipid
C20898  Lipoteichoic acid
C20991  1,2-Diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol
Reference
PMID:8662716
  Authors
Norbeck J, Pahlman AK, Akhtar N, Blomberg A, Adler L.
  Title
Purification and characterization of two isoenzymes of DL-glycerol-3-phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway.
  Journal
J Biol Chem 271:13875-81 (1996)
DOI:10.1074/jbc.271.23.13875
Reference
PMID:8995384
  Authors
Karlsson OP, Dahlqvist A, Vikstrom S, Wieslander A.
  Title
Lipid dependence and basic kinetics of the purified 1,2-diacylglycerol 3-glucosyltransferase from membranes of Acholeplasma laidlawii.
  Journal
J Biol Chem 272:929-36 (1997)
DOI:10.1074/jbc.272.2.929
Reference
PMID:11294844
  Authors
Berg S, Edman M, Li L, Wikstrom M, Wieslander A.
  Title
Sequence properties of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii membranes. Recognition of a large group of lipid glycosyltransferases in eubacteria and archaea.
  Journal
J Biol Chem 276:22056-63 (2001)
DOI:10.1074/jbc.M102576200
Related
pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00071  Fatty acid degradation
mmu00564  Glycerophospholipid metabolism
KO pathway
ko00561   
LinkDB

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