KEGG   PATHWAY: aco00010
Entry
aco00010                    Pathway                                
Name
Glycolysis / Gluconeogenesis - Aminobacterium colombiense
Description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
Class
Metabolism; Carbohydrate metabolism
Pathway map
aco00010  Glycolysis / Gluconeogenesis
aco00010

Module
aco_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:aco00010]
aco_M00002  Glycolysis, core module involving three-carbon compounds [PATH:aco00010]
aco_M00003  Gluconeogenesis, oxaloacetate => fructose-6P [PATH:aco00010]
aco_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:aco00010]
Other DBs
GO: 0006096 0006094
Organism
Aminobacterium colombiense [GN:aco]
Gene
Amico_0344  Glucokinase [KO:K00845] [EC:2.7.1.2]
Amico_1366  phosphoglucose isomerase (PGI) [KO:K01810] [EC:5.3.1.9]
Amico_1481  6-phosphofructokinase [KO:K00850] [EC:2.7.1.11]
Amico_1047  fructose-1,6-bisphosphatase, class II [KO:K02446] [EC:3.1.3.11]
Amico_0027  Fructose-bisphosphate aldolase [KO:K11645] [EC:4.1.2.13]
Amico_0571  ketose-bisphosphate aldolase class-II [KO:K01624] [EC:4.1.2.13]
Amico_0836  triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
Amico_0834  glyceraldehyde-3-phosphate dehydrogenase, type I [KO:K00134] [EC:1.2.1.12]
Amico_0835  Phosphoglycerate kinase [KO:K00927] [EC:2.7.2.3]
Amico_0369  phosphonopyruvate decarboxylase-related protein [KO:K15635] [EC:5.4.2.12]
Amico_0558  phosphonopyruvate decarboxylase-related protein [KO:K15635] [EC:5.4.2.12]
Amico_0589  enolase [KO:K01689] [EC:4.2.1.11]
Amico_0733  pyruvate kinase [KO:K00873] [EC:2.7.1.40]
Amico_0763  pyruvate, phosphate dikinase [KO:K01006] [EC:2.7.9.1]
Amico_0764  phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
Amico_1585  catalytic domain of components of various dehydrogenase complexes [KO:K00627] [EC:2.3.1.12]
Amico_1584  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Amico_1583  pyridine nucleotide-disulfide oxidoreductase dimerization region [KO:K00382] [EC:1.8.1.4]
Amico_1315  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00169] [EC:1.2.7.1]
Amico_1316  thiamine pyrophosphate protein domain protein TPP-binding protein [KO:K00170] [EC:1.2.7.1]
Amico_1313  pyruvate/ketoisovalerate oxidoreductase, gamma subunit [KO:K00172] [EC:1.2.7.1]
Amico_1314  pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit [KO:K00171] [EC:1.2.7.1]
Amico_1077  pyruvate ferredoxin/flavodoxin oxidoreductase [KO:K03737] [EC:1.2.7.1 1.2.7.-]
Amico_1018  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00174] [EC:1.2.7.3 1.2.7.11]
Amico_0795  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00174] [EC:1.2.7.3 1.2.7.11]
Amico_1450  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00174] [EC:1.2.7.3 1.2.7.11]
Amico_0512  pyruvate flavodoxin/ferredoxin oxidoreductase domain protein [KO:K00174] [EC:1.2.7.3 1.2.7.11]
Amico_0513  thiamine pyrophosphate protein domain protein TPP-binding protein [KO:K00175] [EC:1.2.7.3 1.2.7.11]
Amico_1017  thiamine pyrophosphate protein domain protein TPP-binding protein [KO:K00175] [EC:1.2.7.3 1.2.7.11]
Amico_0796  thiamine pyrophosphate protein domain protein TPP-binding protein [KO:K00175] [EC:1.2.7.3 1.2.7.11]
Amico_1449  pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit [KO:K00175] [EC:1.2.7.3 1.2.7.11]
Amico_0560  CoA-binding domain protein [KO:K24012] [EC:6.2.1.13]
Amico_0419  Phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
Amico_1563  hypothetical protein [KO:K01610] [EC:4.1.1.49]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00031  D-Glucose
C00033  Acetate
C00036  Oxaloacetate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00084  Acetaldehyde
C00085  D-Fructose 6-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00186  (S)-Lactate
C00197  3-Phospho-D-glycerate
C00221  beta-D-Glucose
C00236  3-Phospho-D-glyceroyl phosphate
C00267  alpha-D-Glucose
C00354  D-Fructose 1,6-bisphosphate
C00469  Ethanol
C00631  2-Phospho-D-glycerate
C00668  alpha-D-Glucose 6-phosphate
C01159  2,3-Bisphospho-D-glycerate
C01172  beta-D-Glucose 6-phosphate
C01451  Salicin
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C06186  Arbutin
C06187  Arbutin 6-phosphate
C06188  Salicin 6-phosphate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y (ed).
  Title
[Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1980)
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Michal G.
  Title
Biochemical Pathways
  Journal
Wiley (1999)
Related
pathway
aco00020  Citrate cycle (TCA cycle)
aco00030  Pentose phosphate pathway
aco00500  Starch and sucrose metabolism
aco00620  Pyruvate metabolism
aco00640  Propanoate metabolism
aco00710  Carbon fixation by Calvin cycle
KO pathway
ko00010   
LinkDB

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