KEGG   PATHWAY: alca00630
Entry
alca00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Alcanivorax sp. ALC70
Class
Metabolism; Carbohydrate metabolism
Pathway map
alca00630  Glyoxylate and dicarboxylate metabolism
alca00630

Module
alca_M00012  Glyoxylate cycle [PATH:alca00630]
alca_M00621  Glycine cleavage system [PATH:alca00630]
Other DBs
GO: 0046487 0043648
Organism
Alcanivorax sp. ALC70 [GN:alca]
Gene
ASALC70_01019  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
ASALC70_03958  acsA_5; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
ASALC70_01568  acsA_2; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
ASALC70_04407  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
ASALC70_04390  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
ASALC70_03765  citA; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
ASALC70_04272  gltA_3; Citrate synthase [KO:K01647] [EC:2.3.3.1]
ASALC70_00942  acn_1; Aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
ASALC70_00237  acnB; Aconitate hydratase B [KO:K01682] [EC:4.2.1.3 4.2.1.99]
ASALC70_03710  fadI_1; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
ASALC70_03922  fadA_4; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
ASALC70_00436  fadA_1; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
ASALC70_00689  thlA_1; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
ASALC70_01011  thlA_2; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
ASALC70_01320  hypothetical protein [KO:K00626] [EC:2.3.1.9]
ASALC70_01887  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
ASALC70_02905  fadA_2; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
ASALC70_02725  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
ASALC70_02723  putative FAD-linked oxidoreductase [KO:K11472] [EC:1.1.99.14]
ASALC70_02722  lutA; Lactate utilization protein A [KO:K11473] [EC:1.1.99.14]
ASALC70_00321  katE_2; Catalase C [KO:K03781] [EC:1.11.1.6]
ASALC70_02506  katA; Catalase [KO:K03781] [EC:1.11.1.6]
ASALC70_02652  Putative 2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
ASALC70_00359  gph_1; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
ASALC70_01738  glnA; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
ASALC70_01800  Glutamate--methylamine ligase [KO:K01915] [EC:6.3.1.2]
ASALC70_02984  glyA; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
ASALC70_02063  gcvPA; putative glycine dehydrogenase (decarboxylating) subunit 1 [KO:K00282] [EC:1.4.4.2]
ASALC70_02062  gcvPB_2; putative glycine dehydrogenase (decarboxylating) subunit 2 [KO:K00283] [EC:1.4.4.2]
ASALC70_02065  gcvT; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
ASALC70_04281  lpd_2; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
ASALC70_02064  gcvH; Glycine cleavage system H protein [KO:K02437]
ASALC70_02864  ttuD_2; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
ASALC70_01295  ttuC'; putative tartrate dehydrogenase/decarboxylase TtuC' [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
ASALC70_02075  hypothetical protein [KO:K00126] [EC:1.17.1.9]
ASALC70_02074  fdhF; Formate dehydrogenase H [KO:K00123] [EC:1.17.1.9]
ASALC70_02072  hndC; NADP-reducing hydrogenase subunit HndC [KO:K00124]
ASALC70_02071  hndA; NADP-reducing hydrogenase subunit HndA [KO:K00127]
ASALC70_00383  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
ASALC70_03319  fmdA; Formamidase [KO:K01455] [EC:3.5.1.49]
ASALC70_01809  amiF; Formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
alca00010  Glycolysis / Gluconeogenesis
alca00020  Citrate cycle (TCA cycle)
alca00030  Pentose phosphate pathway
alca00053  Ascorbate and aldarate metabolism
alca00071  Fatty acid degradation
alca00230  Purine metabolism
alca00250  Alanine, aspartate and glutamate metabolism
alca00260  Glycine, serine and threonine metabolism
alca00620  Pyruvate metabolism
alca00710  Carbon fixation by Calvin cycle
alca00750  Vitamin B6 metabolism
alca00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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