KEGG   PATHWAY: bcep00630
Entry
bcep00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia cepacia ATCC 25416
Class
Metabolism; Carbohydrate metabolism
Pathway map
bcep00630  Glyoxylate and dicarboxylate metabolism
bcep00630

Module
bcep_M00012  Glyoxylate cycle [PATH:bcep00630]
bcep_M00621  Glycine cleavage system [PATH:bcep00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia cepacia ATCC 25416 [GN:bcep]
Gene
APZ15_15205  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
APZ15_27635  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
APZ15_10295  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
APZ15_28140  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
APZ15_22245  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
APZ15_33075  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
APZ15_16275  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
APZ15_15225  malate synthase [KO:K01638] [EC:2.3.3.9]
APZ15_24705  malate synthase G [KO:K01638] [EC:2.3.3.9]
APZ15_19625  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
APZ15_19590  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
APZ15_37745  citrate synthase [KO:K01647] [EC:2.3.3.1]
APZ15_38130  citrate synthase [KO:K01647] [EC:2.3.3.1]
APZ15_29675  excisionase [KO:K01647] [EC:2.3.3.1]
APZ15_19645  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
APZ15_29550  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
APZ15_31065  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APZ15_31095  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APZ15_01725  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APZ15_33065  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APZ15_37385  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APZ15_13900  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APZ15_14465  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APZ15_32675  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
APZ15_01720  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
APZ15_13895  3-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
APZ15_29875  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
APZ15_24685  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
APZ15_07255  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
APZ15_24690  glcE; glycolate oxidase [KO:K11472] [EC:1.1.99.14]
APZ15_07250  glcE; glycolate oxidase [KO:K11472] [EC:1.1.99.14]
APZ15_24695  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
APZ15_07245  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
APZ15_37300  catalase [KO:K03781] [EC:1.11.1.6]
APZ15_35810  catalase [KO:K03781] [EC:1.11.1.6]
APZ15_03985  catalase [KO:K03781] [EC:1.11.1.6]
APZ15_02695  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
APZ15_38240  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
APZ15_34820  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
APZ15_13515  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
APZ15_09225  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
APZ15_13085  glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
APZ15_06230  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
APZ15_28595  hydrolase [KO:K01091] [EC:3.1.3.18]
APZ15_09270  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
APZ15_29115  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
APZ15_25715  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
APZ15_15990  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
APZ15_02870  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
APZ15_16065  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
APZ15_28450  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
APZ15_27470  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
APZ15_07650  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
APZ15_04660  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
APZ15_04670  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
APZ15_37905  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
APZ15_11385  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
APZ15_15915  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
APZ15_09900  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
APZ15_04665  hypothetical protein [KO:K02437]
APZ15_14340  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
APZ15_14345  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
APZ15_14585  glycerate kinase [KO:K00865] [EC:2.7.1.165]
APZ15_26500  aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
APZ15_24900  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
APZ15_38325  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
APZ15_20685  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
APZ15_06880  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
APZ15_30155  cupin [KO:K01569] [EC:4.1.1.2]
APZ15_36670  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
APZ15_08850  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
APZ15_08855  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
APZ15_19340  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
APZ15_19345  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
APZ15_19335  formate dehydrogenase [KO:K00124]
APZ15_08860  formate dehydrogenase [KO:K00124]
APZ15_19330  formate dehydrogenase [KO:K00127]
APZ15_08865  formate dehydrogenase [KO:K00127]
APZ15_13105  esterase [KO:K01432] [EC:3.5.1.9]
APZ15_00800  kynurenine formamidase [KO:K07130] [EC:3.5.1.9]
APZ15_01770  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
APZ15_27530  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
APZ15_16075  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bcep00010  Glycolysis / Gluconeogenesis
bcep00020  Citrate cycle (TCA cycle)
bcep00030  Pentose phosphate pathway
bcep00053  Ascorbate and aldarate metabolism
bcep00071  Fatty acid degradation
bcep00230  Purine metabolism
bcep00250  Alanine, aspartate and glutamate metabolism
bcep00260  Glycine, serine and threonine metabolism
bcep00620  Pyruvate metabolism
bcep00710  Carbon fixation by Calvin cycle
bcep00750  Vitamin B6 metabolism
bcep00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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