KEGG   PATHWAY: bcew00630
Entry
bcew00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia cenocepacia DWS 37E-2
Class
Metabolism; Carbohydrate metabolism
Pathway map
bcew00630  Glyoxylate and dicarboxylate metabolism
bcew00630

Module
bcew_M00012  Glyoxylate cycle [PATH:bcew00630]
bcew_M00621  Glycine cleavage system [PATH:bcew00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia cenocepacia DWS 37E-2 [GN:bcew]
Gene
DM40_4470  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
DM40_2684  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
DM40_4924  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM40_5668  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM40_1974  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM40_2836  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM40_5433  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM40_5495  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM40_2688  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
DM40_3388  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
DM40_3939  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DM40_170  merR regulatory family protein [KO:K01647] [EC:2.3.3.1]
DM40_3946  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DM40_3935  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
DM40_5254  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
DM40_5298  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM40_2504  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM40_2388  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM40_374  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM40_5431  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM40_5496  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM40_4419  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
DM40_2387  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DM40_373  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DM40_1426  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
DM40_1425  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
DM40_1424  4Fe-4S dicluster domain protein [KO:K11473] [EC:1.1.99.14]
DM40_5278  catA; catechol 1,2-dioxygenase [KO:K03781] [EC:1.11.1.6]
DM40_5177  catalase family protein [KO:K03781] [EC:1.11.1.6]
DM40_789  catalase family protein [KO:K03781] [EC:1.11.1.6]
DM40_5802  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DM40_558  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DM40_2345  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DM40_1766  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DM40_1775  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
DM40_4833  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
DM40_1237  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
DM40_2789  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
DM40_2809  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DM40_590  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DM40_4859  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DM40_3575  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
DM40_5055  serine hydroxymethyltransferase family protein [KO:K00600] [EC:2.1.2.1]
DM40_1469  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
DM40_3011  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
DM40_917  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
DM40_919  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
DM40_2775  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM40_1901  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM40_2137  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM40_918  gcvH; glycine cleavage system H protein [KO:K02437]
DM40_2474  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DM40_2475  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DM40_2476  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DM40_2527  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
DM40_3421  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DM40_1359  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DM40_4586  oxdD; oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]
DM40_1691  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
DM40_3985  molybdopterin oxidoreductase Fe4S4 domain protein [KO:K00123] [EC:1.17.1.9]
DM40_3986  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DM40_1692  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DM40_5106  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DM40_1693  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
DM40_3987  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
DM40_1694  thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]
DM40_3988  formate dehydrogenase, gamma subunit [KO:K00127]
DM40_2315  alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]
DM40_211  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
DM40_5019  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM40_382  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM40_2811  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bcew00010  Glycolysis / Gluconeogenesis
bcew00020  Citrate cycle (TCA cycle)
bcew00030  Pentose phosphate pathway
bcew00053  Ascorbate and aldarate metabolism
bcew00071  Fatty acid degradation
bcew00230  Purine metabolism
bcew00250  Alanine, aspartate and glutamate metabolism
bcew00260  Glycine, serine and threonine metabolism
bcew00620  Pyruvate metabolism
bcew00710  Carbon fixation by Calvin cycle
bcew00750  Vitamin B6 metabolism
bcew00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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