KEGG   PATHWAY: bmus00630
Entry
bmus00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Balaenoptera musculus (blue whale)
Class
Metabolism; Carbohydrate metabolism
Pathway map
bmus00630  Glyoxylate and dicarboxylate metabolism
bmus00630

Module
bmus_M00621  Glycine cleavage system [PATH:bmus00630]
bmus_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:bmus00630]
Other DBs
GO: 0046487 0043648
Organism
Balaenoptera musculus (blue whale) [GN:bmus]
Gene
118881045  ACSS2; acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
118881083  ACSS1; acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1 [KO:K01895] [EC:6.2.1.1]
118905888  MDH1; malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
118881004  MDH2; malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
118901798  CS; citrate synthase, mitochondrial isoform X1 [KO:K01647] [EC:2.3.3.1]
118902121  ACO2; aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
118896521  ACO1; cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
118905047  ACAT2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
118899203  ACAT1; acetyl-CoA acetyltransferase, mitochondrial isoform X1 [KO:K00626] [EC:2.3.1.9]
118890768  MCEE; methylmalonyl-CoA epimerase, mitochondrial isoform X1 [KO:K05606] [EC:5.1.99.1]
118883970  PCCA; propionyl-CoA carboxylase alpha chain, mitochondrial isoform X1 [KO:K01965] [EC:6.4.1.3]
118894646  PCCB; propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
118903617  MMUT; methylmalonyl-CoA mutase, mitochondrial isoform X1 [KO:K01847] [EC:5.4.99.2]
118899391  HAO2; hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
118880715  HAO1; hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
118899997  CAT; catalase isoform X1 [KO:K03781] [EC:1.11.1.6]
118896801  GRHPR; glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
118882009  glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
118898116  AGXT; serine--pyruvate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
118900178  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
118896548  GLUL; glutamine synthetase isoform X1 [KO:K01915] [EC:6.3.1.2]
118886575  SHMT1; serine hydroxymethyltransferase, cytosolic isoform X1 [KO:K00600] [EC:2.1.2.1]
118901928  SHMT2; serine hydroxymethyltransferase, mitochondrial isoform X1 [KO:K00600] [EC:2.1.2.1]
118896876  GLDC; glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
118903779  AMT; aminomethyltransferase, mitochondrial isoform X1 [KO:K00605] [EC:2.1.2.10]
118898130  LOW QUALITY PROTEIN: dihydrolipoyl dehydrogenase, mitochondrial-like [KO:K00382] [EC:1.8.1.4]
118900721  DLD; LOW QUALITY PROTEIN: dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
118885262  GCSH; glycine cleavage system H protein, mitochondrial [KO:K02437]
118893345  glycine cleavage system H protein, mitochondrial-like isoform X1 [KO:K02437]
118887075  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
118893621  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
118901030  glycine cleavage system H protein, mitochondrial [KO:K02437]
118888495  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
118894893  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
118896135  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
118902442  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
118883331  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
118892714  HYI; putative hydroxypyruvate isomerase isoform X1 [KO:K01816] [EC:5.3.1.22]
118904149  GLYCTK; glycerate kinase isoform X1 [KO:K11529] [EC:2.7.1.165]
118882584  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
118886129  AFMID; kynurenine formamidase isoform X1 [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bmus00010  Glycolysis / Gluconeogenesis
bmus00020  Citrate cycle (TCA cycle)
bmus00030  Pentose phosphate pathway
bmus00053  Ascorbate and aldarate metabolism
bmus00071  Fatty acid degradation
bmus00230  Purine metabolism
bmus00250  Alanine, aspartate and glutamate metabolism
bmus00260  Glycine, serine and threonine metabolism
bmus00620  Pyruvate metabolism
bmus00750  Vitamin B6 metabolism
bmus00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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